19 unknown, 12 completed, 2 recruiting, 1 not yet recruiting. 14 Phase 3, 12 Phase 2, 6 Phase 1, 6 Phase 4, 2 Not applicable.
Follow Thrombopoietin: new trials by email Literature Review of Thrombopoietin trials Research Report on Thrombopoietin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Romiplostim Versus rhTPO for Platelet Engraftment After Transplant in MDS and AA Romiplostim, Recombinant Human Thrombopoietin - MDS (Myelodysplastic Syndrome), Aplastic Anemia (AA) | Phase 2 | Recruiting | The First Affiliated Hospital of Soochow University | 66 | 2026-01-31 | 2026-04-15 |
| Lusutrombopag Combined With Recombinant Human Thrombopoietin for the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Destined to Undergo Elective Invasive Surgery Lusutrombopag combined with recombinant human thrombopoietin - Thrombocytopenia | Phase 2 | Recruiting | Anhui Provincial Hospital | 60 | 2024-11-10 | 2024-11-05 |
| Phase I Study to Evaluate rhTPO in Healthy Caucasian Volunteers Recombinant human thrombopoietin for injection (rhTPO) - Healthy Subjects | Phase 1 | Completed | 3SBIO AU PTY LTD | 22 | 2024-10-03 | 2025-04-22 |
| A Multicenter Randomized Controlled Study on the Treatment of Refractory CTIT With Romiplostim N01 Compared to Recombinant Human Thrombopoietin Romiplostim N01, Recombinant Human Thrombopoietin - CTIT-Chemotherapy Induced Thrombocytopenia | Phase 3 | Unknown | Shandong University | 60 | 2024-06-01 | 2024-06-04 |
| Decitabine and Umbilical Cord Blood for Poor Graft Function Post Allo-HSCT decitabine, umbilical cord blood, Granulocyte-colony stimulating factor - Poor Graft Function | Phase 3 | Not yet recruiting | The First Affiliated Hospital of Soochow University | 100 | 2023-08-01 | 2023-06-09 |
| IVIg Plus Low Dose rhTPO for ITP in Pregnancy intravenous immunoglobulin plus low dose recombinant human thrombopoietin (rhTPO), intravenous immunoglobulin - Immune Thrombocytopenia, Pregnancy Related | Phase 2 | Unknown | Peking University People's Hospital | 50 | 2023-01-01 | 2022-12-02 |
| A Randomized Trial Comparing Optimized rhTPO Treatment With Eltrombopag Treatment in Pre-treated ITP Pts rhTPO, Eltrombopag - Previously Treated Primary Immune Thrombocytopenia | Phase 4 | Completed | Institute of Hematology & Blood Diseases Hospital, China | 157 | 2022-11-22 | 2025-04-24 |
| Efficacy and Safety of rhTPO's Prophylactic Treatment of CTIT in Patients With High Risk of Cardiac Injury rhTPO, Control - Cancer Treatment Induced Thrombocytopenia | Phase 4 | Unknown | The First Affiliated Hospital of Dalian Medical University | 165 | 2022-06-06 | 2024-03-01 |
| Effects of Recombinant Human Thrombopoietin on Platelet Levels in ICU Patients recombinant human thrombopoietin, normal saline - Pneumonia, Thrombocytopenia | Phase 4 | Unknown | Nanfang Hospital, Southern Medical University | 178 | 2022-02-01 | 2022-02-01 |
| A Phase Ib Clinical Study for rhTPO in the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease recombinant human thrombopoietin injection - Liver Disease Chronic, Thrombocytopenia | Phase 1 | Unknown | Shenyang Sunshine Pharmaceutical Co., LTD. | 54 | 2022-01-16 | 2022-01-14 |
| The Combination of Prednisone and Recombinant Human Thrombopoietin for Treatment of Immune Thrombocytopenia in Pregnancy Prednisone, Recombinant Human TPO - Immune Thrombocytopenia | Phase 2 | Unknown | Peking University People's Hospital | 90 | 2021-06-01 | 2022-04-19 |
| A Randomized Trial of rhTPO Versus Placebo for Low/Intermediate-1 Risk MDS With Thrombocytopenia Danazol + rhTPO (recombinant human thrombopoietin injection), Danazol + sodium chloride - Low/Intermediate Risk-1 MDS | Phase 2 / Phase 3 | Unknown | Peking Union Medical College Hospital | 75 | 2020-03-01 | 2020-03-27 |
| A Study of Eltrombopag and Recombinant Human Thrombopoietin In Primary Immune Thrombocytopenia Eltrombopag, Recombinant human thrombopoietin (rh-TPO) - Corticosteroid-resistant or Relapsed ITP | Unknown | Peking University People's Hospital | 100 | 2020-01-01 | 2020-10-20 | |
| The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia rhTPO, Placebo - Sepsis, Thrombocytopenia | Phase 2 / Phase 3 | Unknown | Ruilan Wang | 200 | 2019-04-01 | 2024-04-18 |
| High-dose Use of rhTPO in CIT Patients rhTPO - Thrombocytopenia | Phase 4 | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 50 | 2018-09-28 | 2018-10-30 |
| The Tolerability，Safety，PK/PD Study of rhTPO in the Patients With Liver Function Impairment Recombinant human thrombopoietin, Placebo, recombinant human thrombopoietin - Liver Cirrhosis | Early Phase 1 | Unknown | Shenyang Sunshine Pharmaceutical Co., LTD. | 58 | 2018-06-28 | 2020-03-23 |
| Recombinant Human Thrombopoietin(rhTPO) in Pregnancy With Immune Thrombocytopenia recombinant human thrombopoietin, Platelet Concentrate - Immune Thrombocytopenia | Phase 3 | Unknown | Shandong University | 90 | 2018-05-01 | 2018-04-10 |
| Efficacy and Safety of Thrombopoietin In Patients With Severe and Very Severe Aplastic Anemia rhTPO, placebo - Anemia, Aplastic | Phase 2 | Unknown | Tianjin Medical University General Hospital | 250 | 2016-08-01 | 2016-08-05 |
| Recombinant Human Thrombopoietin for Mobilization of Peripheral Blood Progenitor Cells for Autologous Transplantation Recombinant Human Thrombopoietin - Thrombocytopoietin, Hematopoietic Stem Cell Mobilization | Phase 1 / Phase 2 | Unknown | Hongnan Mo | 50 | 2016-06-01 | 2019-12-06 |
| Prospective Study of Patients With Thrombocytopenia Following HSCT Decitabine, rhTPO, Conventional Treatment - Thrombocytopenia, Hematologic Diseases | Phase 3 | Completed | The First Affiliated Hospital of Soochow University | 97 | 2015-10-01 | 2020-05-06 |
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Purpura, Thrombocytopenic, Idiopathic (11) · Thrombocytopenia (11) · Purpura (4) · Jacobs syndrome (3) · Anemia, Aplastic (2) · Hematologic Diseases (2) · Multiple Myeloma (2) · Neuroblastoma (2) · Osteosarcoma (2) · Anemia, Refractory, with Excess of Blasts (1) · Astrocytoma (1) · Breast Neoplasms (1) · Breast Neoplasms, Male (1) · Burkitt Lymphoma (1) · Carcinoma, Non-Small-Cell Lung (1)
Shandong University (6) · The First Affiliated Hospital of Soochow University (4) · Nanfang Hospital, Southern Medical University (3) · Peking University People's Hospital (3) · Institute of Hematology & Blood Diseases Hospital, China (2) · Shenyang Sunshine Pharmaceutical Co., LTD. (2) · 3SBIO AU PTY LTD (1) · Anhui Provincial Hospital (1) · Children's Oncology Group (1) · Chinese Society of Lung Cancer (1) · First Affiliated Hospital Xi'an Jiaotong University (1) · Hongnan Mo (1) · M.D. Anderson Cancer Center (1) · Ming Hou (1) · Northwestern University (1)
China (27) · United States (4) · Australia (2)
Ming Hou, Dr. (2) · Arockiaa Philo Aarthy Joseph, Ph.D (1) · Depei Wu, PhD,MD (1) · Hou Ming, Dr. (1) · Jane N. Winter, MD (1) · Jia Chen, Doctor (1) · Jianxiang Wang, Dr (1) · Jing Sun, MD (1) · Lei Zhang, MD (1) · Lianxin Liu (1) · Lingxiao Zhang, doctor (1) · Minf Hou, Dr. (1) · Ming Hou, Dr (1) · Ming Hou,, Dr (1) · Mitchell S. Cairo, MD (1)
PMID 12944568, PMID 17077333, PMID 19005182, PMID 19846889, PMID 33646303, PMID 15814645, PMID 16818281, PMID 18510702, PMID 19117511, PMID 21713321, PMID 25566808, PMID 25575541, PMID 26181032, PMID 27088376, PMID 31492102, PMID 32871029, PMID 34492685, PMID 34505019, PMID 34778037, PMID 36535011, PMID 3881142, PMID 40896456