2 completed, 1 active not recruiting. 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Active not recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Pulmonary TB: new trials by email Literature Review of Pulmonary TB trials Research Report on Pulmonary TB
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary Tuberculosis sorfequiline, Pretomanid, Linezolid - Pulmonary TB, Pulmonary Tuberculosis | Phase 2 | Active not recruiting | Global Alliance for TB Drug Development | 309 | 2023-10-31 | 2026-06-24 |
| Safety and Efficacy Evaluation of 4-month Regimen of OPC-167832, Delamanid and Bedaquiline in Participants With Drug-Susceptible Pulmonary TB Delamanid, Bedaquiline, RHEZ - Pulmonary TB | Phase 2 | Completed | Otsuka Pharmaceutical Development & Commercialization, Inc. | 122 | 2022-04-12 | 2026-08-12 |
| A Phase 1/2 Trial of Multiple Oral Doses of OPC-167832 for Uncomplicated Pulmonary Tuberculosis 10 mg OPC-167832, 30 mg OPC-167832, 90 mg OPC-167832 - Pulmonary TB | Phase 1 / Phase 2 | Completed | Otsuka Pharmaceutical Development & Commercialization, Inc. | 122 | 2018-10-18 | 2023-11-18 |
Tuberculosis, Pulmonary (3) · Tuberculosis (1)
Actinomycetales Infections (3) · Bacterial Infections (3) · Bacterial Infections and Mycoses (3) · Gram-Positive Bacterial Infections (3) · Infections (3) · Lung Diseases (3) · Mycobacterium Infections (3) · Respiratory Tract Diseases (3) · Respiratory Tract Infections (3) · Tuberculosis (2)
Isoniazid (2) · OPC-67683 (2) · Rifampin (2) · bedaquiline (2) · Ethambutol (1) · Linezolid (1) · Protons (1) · Pyrazinamide (1) · TBAJ-876 (1) · pretomanid (1)
Otsuka Pharmaceutical Development & Commercialization, Inc. (2) · Global Alliance for TB Drug Development (1)
South Africa (3) · Georgia (1) · Philippines (1) · Tanzania (1) · Uganda (1)
Morounfolu Olugbosi, MD (1) · Prof. Andreas Diacon (1) · Prof. Rodney Dawson, MD (1) · Veronique R de Jager, MD (1)
PMID 38243296, PMID 39612928, PMID 39651910, PMID 41121745, PMID 41616265, PMID 42214407