2 completed, 1 active not recruiting, 1 recruiting. 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Active not recruiting 1, Recruiting 1 |
Follow TBAJ-876: new trials by email Literature Review of TBAJ-876 trials Research Report on TBAJ-876
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sorfequiline-based Regimens in Adults With Newly Diagnosed Drug-sensitive Pulmonary TB sorfequiline, Pretomanid, Linezolid - Tuberculosis, Pulmonary | Phase 2 | Recruiting | Global Alliance for TB Drug Development | 100 | 2026-07-09 | 2026-08-19 |
| Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary Tuberculosis sorfequiline, Pretomanid, Linezolid - Pulmonary TB, Pulmonary Tuberculosis | Phase 2 | Active not recruiting | Global Alliance for TB Drug Development | 309 | 2023-10-31 | 2026-06-24 |
| A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults TBAJ-876, Midazolam, Digoxin - Pulmonary Disease, Tuberculosis, Pulmonary | Phase 1 | Completed | Global Alliance for TB Drug Development | 28 | 2022-06-30 | 2024-10-08 |
| Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults TBAJ-876 suspension, Placebo suspension, TBAJ-876 100 mg tablet - Pulmonary Disease, Tuberculosis, Pulmonary | Phase 1 | Completed | Global Alliance for TB Drug Development | 137 | 2020-06-08 | 2025-06-04 |
Tuberculosis (4) · Tuberculosis, Pulmonary (4) · Lung Diseases (2) · Tuberculosis, Multidrug-Resistant (2)
Global Alliance for TB Drug Development (4)
South Africa (2) · Tanzania (2) · United States (2) · Georgia (1) · Philippines (1) · Uganda (1)
Antonio Lombardi, MD (2) · Morounfolu Olugbosi (1) · Morounfolu Olugbosi, MD (1)