10 completed, 4 recruiting, 2 terminated, 2 unknown. 18 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 18 | Completed 10, Recruiting 4, Terminated 2, Unknown 2 |
Follow Pulmonary Emphysema: new trials by email Literature Review of Pulmonary Emphysema trials Research Report on Pulmonary Emphysema
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Unilateral vs. Bilateral Lung Volume Reduction Surgery Unilateral LVRS, Bilateral LVRS - Emphysema, Pulmonary | Not applicable | Recruiting | Copenhagen University Hospital, Rigshospitalet | 146 | 2025-03-21 | 2026-07-28 |
| The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema Endobronchial Therman Liquid Ablation (ETLA) - Emphysema or COPD, Emphysema | Not applicable | Recruiting | Morair Medtech, LLC | 30 | 2025-01-10 | 2025-01-28 |
| Clinical-ultrasonographic Assessment of Pulmonary Emphysema Relationship between lung ultrasound and computed tomographic scan - Emphysema, Pulmonary Emphysema | Not applicable | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 1628 | 2024-09-04 | 2026-05-22 |
| An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema AeriSeal System - Emphysema, Pulmonary, Emphysema or COPD | Not applicable | Recruiting | Pulmonx Corporation | 200 | 2024-02-22 | 2026-09-17 |
| Video Assisted Thoracic Surgery (VATS) Fissure Completion Prior to Zephyr® Endobronchial Valve Insertion Video-assisted thoracoscopic surgery (VATS) fissure completion, Zephyr Valve insertion - Pulmonary Emphysema | Not applicable | Completed | Pulmonx Corporation | 9 | 2020-06-04 | 2025-04-29 |
| Clinical Study to Evaluate the Exercise Capacity in Patients With Severe Emphysema Treated With Coils 10 coils in upper lobes, 15 coils in upper and lower lobes, cycloergometry - Pulmonary Emphysema | Not applicable | Unknown | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 35 | 2016-11-01 | 2019-03-01 |
| A Prospective Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the OL-BF-001 for Severe Emphysema OL-BF-001 - Emphysema | Not applicable | Terminated | Olympus Corporation | 38 | 2015-08-01 | 2019-08-28 |
| Diagnostic Value of Ultralow-dose Computed Tomography for the Detection of Pulmonary Nodules and Lung Parenchym Alterations Compared to Standard-dose CT Ultralow-Dose-CT - Multiple Pulmonary Nodules, Pulmonary Emphysema | Not applicable | Unknown | Cantonal Hospital of St. Gallen | 500 | 2015-01-01 | 2016-01-27 |
| Prevalence of Alpha-1 Antitrypsin Dysfunction in Pulmonary Emphysema Blood sampling - Pulmonary Emphysema | Not applicable | Completed | Hospices Civils de Lyon | 190 | 2014-12-01 | 2015-12-07 |
| In Vivo Endomicroscopic Description of Pulmonary Microcirculation in Systemic Sclerosis and Emphysema Patients Bronchoscopy with in vivo confocal endomicroscopy - Pulmonary Disease, Pulmonary Emphysema | Not applicable | Terminated | University Hospital, Rouen | 9 | 2014-11-24 | 2026-04-14 |
| The Spiration Valve System for the Treatment of Severe Emphysema Spiration Valve System, Medical Management - Empyhsema, Pulmonary Disease, Chronic Obstructive | Not applicable | Completed | Olympus Corporation of the Americas | 107 | 2013-11-08 | 2018-02-14 |
| Evaluation of the Spiration® Valve System for Emphysema to Improve Lung Function Spiration Valve System, Medical Management - Emphysema | Not applicable | Completed | Olympus Corporation of the Americas | 172 | 2013-06-01 | 2024-05-31 |
| Safety Study of Bone-marrow Derived Mesenchymal Stromal Cells Associated With Endobronchial Valves in Emphysema Bronchoscopy - Pulmonary Emphysema | Not applicable | Completed | Hospital de Clinicas de Porto Alegre | 10 | 2013-05-01 | 2015-03-25 |
| eRT Remote Health Monitoring Remote Health Monitoring - Pulmonary Disease, Chronic Obstructive, COPD | Not applicable | Completed | University of California, Los Angeles | 17 | 2012-01-01 | 2020-05-01 |
| Implantation of Endobronchial Valves Versus Intrabronchial Valves in Patients With Severe Heterogeneous Emphysema EBV implantation, IBV implantation - Pulmonary Emphysema | Not applicable | Completed | Heidelberg University | 60 | 2011-08-01 | 2022-07-07 |
| A Phase I Study of iPS Cell Generation From Patients With COPD Skin Biopsy - Thoracic Diseases, Respiratory Tract Diseases | Not applicable | Completed | Mayo Clinic | 31 | 2009-09-01 | 2022-09-28 |
| Safety Study of Cell Therapy to Treat Chronic Obstructive Pulmonary Disease Stem cells stimulation, stem cells collection, stem cells infusion - Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema | Not applicable | Completed | UPECLIN HC FM Botucatu Unesp | 4 | 2009-05-01 | 2012-03-26 |
| Innovation in Pulmonary Rehabilitation Breathing retraining, Heliox, Exercise - Pulmonary Disease, Pulmonary Emphysema | Not applicable | Completed | US Department of Veterans Affairs | 103 | 2005-10-01 | 2014-10-16 |
Pulmonary Disease, Chronic Obstructive (8) · Emphysema (7) · Lung Diseases (5) · Respiratory Tract Diseases (5) · Lung Diseases, Obstructive (2) · Pathologic Processes (2) · Behavior (1) · Bronchitis, Chronic (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Small Cell (1) · Disease (1) · Dyspnea (1) · Lung Neoplasms (1) · Multiple Pulmonary Nodules (1)
Chronic Disease (18) · Disease Attributes (18) · Pathological Conditions, Signs and Symptoms (18) · Lung Diseases, Obstructive (16) · Pathologic Processes (16) · Lung Diseases (13) · Respiratory Tract Diseases (13) · Pulmonary Disease, Chronic Obstructive (10) · Neoplasms by Site (2) · Respiratory Tract Neoplasms (2) · Thoracic Neoplasms (2) · Bronchial Diseases (1) · Bronchial Neoplasms (1) · Bronchitis (1) · Carcinoma (1)
Bronchoscopy (2) · Pneumonectomy (2) · Practice Management, Medical (2) · Blood Specimen Collection (1) · Exercise (1) · Thoracic Surgery, Video-Assisted (1) · heliox (1)
Olympus Corporation of the Americas (2) · Pulmonx Corporation (2) · Cantonal Hospital of St. Gallen (1) · Copenhagen University Hospital, Rigshospitalet (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Heidelberg University (1) · Hospices Civils de Lyon (1) · Hospital de Clinicas de Porto Alegre (1) · Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz (1) · Mayo Clinic (1) · Morair Medtech, LLC (1) · Olympus Corporation (1) · UPECLIN HC FM Botucatu Unesp (1) · US Department of Veterans Affairs (1) · University Hospital, Rouen (1)
United States (5) · France (3) · Germany (3) · Australia (2) · Austria (2) · Brazil (2) · Denmark (2) · Italy (2) · Netherlands (2) · Spain (2) · Canada (1) · China (1) · Japan (1) · Switzerland (1) · United Kingdom (1)
Aldemir Bilaqui, MD (1) · Christopher B Cooper, M.D. (1) · Dennis A Wigle, MD, PhD (1) · Eileen G. Collins, PhD RN (1) · Hugo G Oliveira, MD, PhD (1) · Iker Fernandez-Navamuel, MD, PhD (1) · Mario R Lago, Ms (1) · Milton A Ruiz, MD (1) · Nanshan Zhong, MD (1) · Narinder Shargill, PhD (1) · Naveed Alam, MD (1) · Oswaldo T Greco, MD (1)
PMID 21311694, PMID 24238770, PMID 24287082, PMID 31365298, PMID 37948704, PMID 38364975