13 completed, 1 terminated, 1 unknown, 1 withdrawn. 8 Not applicable, 5 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 5, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 5 | Completed 5 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
Follow heliox: new trials by email Literature Review of heliox trials Research Report on heliox
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Heliox on the Work of Breathing in Adult Patients With Lower Airway Stenosis Heliox, Oxygen - Airway Obstruction | Completed | Hospital Universitario 12 de Octubre | 18 | 2022-04-27 | 2026-09-23 | |
| Limitation of the Ventilatory Response to Exercise in the Master Athlete Heliox, Air - Healthy Volunteers | Not applicable | Terminated | Centre Hospitalier Universitaire de Nice | 3 | 2022-04-01 | 2023-09-08 |
| Effects of Non-invasive Ventilation With Helium-oxygen Mixture in Premature Infants With Respiratory Distress Syndrome heliox - Respiratory Distress Syndrome, Premature Infants | Phase 1 / Phase 2 | Completed | Poznan University of Medical Sciences | 23 | 2017-01-01 | 2020-06-09 |
| HELIox CardiOPlegia Trial During Cardiac surgERy Heliox, Standard of care - C.Surgical Procedure; Cardiac | Not applicable | Unknown | Unity Health Toronto | 24 | 2016-04-01 | 2016-05-03 |
| Aerosol Deposition in Asthmatic Obese Women Using Heliox nebulizing with heliox and oxygen - Obese, Asthma | Phase 2 | Completed | Jacqueline de Melo Barcelar | 20 | 2015-11-01 | 2016-09-15 |
| Effect of Heliox on RSV Bronchiolitis Heliox, Air - RSV Infection, Acute Bronchiolitis | Phase 3 | Completed | Wael Seliem | 104 | 2015-05-01 | 2017-05-31 |
| Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study C Administration of gas mixtures - Sleep Apnea | Not applicable | Withdrawn | Brigham and Women's Hospital | 2012-12-08 | 2019-07-11 | |
| Heliox in Preterm Infants With Respiratory Distress Syndrome heliox - Respiratory Distress Syndrome | Not applicable | Completed | Third Military Medical University | 36 | 2012-12-01 | 2013-10-28 |
| The Use of Heliox in Obstructive Sleep Apnea Syndrome Heliox - Obstructive Sleep Apnea Syndrome | Phase 2 | Completed | Northwell Health | 32 | 2009-12-01 | 2015-06-01 |
| Use of Heliox Associated With PEEP in Patients With Asthma Heliox+PEP, Oxygen+PEP, Heliox - Asthma, Helium | Not applicable | Completed | Universidade Federal de Pernambuco | 32 | 2009-07-01 | 2010-12-30 |
| Plethysmography Opto-electronic and Asthma Oxygen, Heliox, PEEP - Asthma | Not applicable | Completed | Universidade Federal de Pernambuco | 27 | 2009-06-01 | 2013-02-05 |
| Heliox and Posture in Patients With Asthma HELIOX, OXYGEN, HELIOX+POSTURE - Acute Asthma | Not applicable | Completed | Universidade Federal de Pernambuco | 59 | 2008-06-01 | 2009-06-17 |
| NCPAP + Heliox as a Treatment for Infant Respiratory Distress Syndrome (RDS) NCPAP + standard air, NCPAP + Heliox - Respiratory Distress Syndrome, Bronchopulmonary Dysplasia | Phase 2 | Completed | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 51 | 2008-02-01 | 2011-06-28 |
| Heliox in Experimental Upper Airway Obstruction HELIOX - Airway Obstruction, Dyspnea | Phase 1 / Phase 2 | Completed | University of Witten/Herdecke | 44 | 2007-11-01 | 2008-11-21 |
| Innovation in Pulmonary Rehabilitation Breathing retraining, Heliox, Exercise - Pulmonary Disease, Pulmonary Emphysema | Not applicable | Completed | US Department of Veterans Affairs | 103 | 2005-10-01 | 2014-10-16 |
| Heliox-Driven Racemic Epinephrine in Treatment of Bronchiolitis in Pediatric ED Patients heliox, oxygen - Bronchiolitis | Phase 3 | Completed | University of Louisville | 72 | 2004-12-01 | 2020-05-20 |
Asthma (4) · Respiratory Distress Syndrome (3) · Airway Obstruction (2) · Bronchiolitis (1) · Bronchopulmonary Dysplasia (1) · Dyspnea (1) · Lung Diseases (1) · Obesity (1) · Premature Birth (1) · Pulmonary Emphysema (1) · Respiratory Syncytial Virus Infections (1) · Sleep Apnea Syndromes (1) · Sleep Apnea, Obstructive (1)
Universidade Federal de Pernambuco (3) · Brigham and Women's Hospital (1) · Centre Hospitalier Universitaire de Nice (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · Hospital Universitario 12 de Octubre (1) · Jacqueline de Melo Barcelar (1) · Northwell Health (1) · Poznan University of Medical Sciences (1) · Third Military Medical University (1) · US Department of Veterans Affairs (1) · Unity Health Toronto (1) · University of Louisville (1) · University of Witten/Herdecke (1) · Wael Seliem (1)
Brazil (4) · United States (4) · Canada (1) · China (1) · France (1) · Germany (1) · Italy (1) · Poland (1) · Spain (1)
Armele Andrade (1) · David A Wellman, MD (1) · David Mazer, MD (1) · Eileen G. Collins, PhD RN (1) · Hubert Trubel, MD (1) · In K Kim, MD (1) · Leroy Sylvie (1) · Marta Corral Blanco, MD (1) · Michel Chalhoub, MD (1) · Tomasz Szczapa, M.D. PhD (1) · Yuan Shi, MD, PhD (1)
PMID 9925082, PMID 10453854, PMID 10471601, PMID 12793914, PMID 16723037, PMID 1864100, PMID 21352660, PMID 22147778, PMID 22291116, PMID 23664767, PMID 24238770, PMID 30850876, PMID 7842183
R01HL102321 (1)