7 unknown. 7 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Unknown 7 |
| Phase 2 | 3 | Unknown 3 |
Follow Primary Immunodeficiency Diseases: new trials by email Literature Review of Primary Immunodeficiency Diseases trials Research Report on Primary Immunodeficiency Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Bioavailability of Betamethasone Oral Solution Metered Spray (GTX-102) in Healthy Subjects GTX-102 medium dose fast Period 1 and Period 2, GTX-102 medium dose slow Period 1 and Period 2, GTX-102 high dose fast Period 1 and Period 2 - Ataxia Telangiectasia | Phase 1 | Unknown | Grace Therapeutics Inc. | 48 | 2022-09-13 | 2023-01-23 |
| Safety and Early Efficacy Study of TBX-1400 in Patients With Severe Combined Immunodeficiency TBX-1400 - Severe Combined Immunodeficiency | Phase 1 | Unknown | Taiga Biotechnologies, Inc. | 8 | 2021-08-01 | 2020-10-08 |
| Transfer of Effector Memory T Cells (Tem) Following Allogeneic Stem Cell Transplantation CD62L- Tem - Lymphoma, Leukemia | Phase 1 | Unknown | University College, London | 18 | 2019-10-21 | 2019-10-25 |
| Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency Lentiviral vector transduced CD34+ cells - Severe Combined Immunodeficiency, X-Linked | Phase 1 | Unknown | Great Ormond Street Hospital for Children NHS Foundation Trust | 5 | 2018-12-21 | 2023-10-12 |
| ASIS for GAMMAGARD in Primary Immunodeficiency Gadolinium For abdomen, Gadolinium For lower back, Efficacy of Gammagard subcutaneously at Week 12 - Primary Immunodeficiency | Phase 1 / Phase 2 | Unknown | ASIS Corporation | 60 | 2016-01-01 | 2015-06-24 |
| CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant CliniMACS CD34+ Reagent System, Thiotepa, Cyclophosphamide - Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML) | Phase 1 / Phase 2 | Unknown | Diane George | 14 | 2013-06-03 | 2024-06-04 |
| Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined Immunodeficiency CD34+ HSCs transduced with the lentivirus vector, VSV-G pseudotyped CL20-4i-EF1α-hγc-OPT, Palifermin, Busulfan - X-Linked Combined Immunodeficiency Diseases | Phase 1 / Phase 2 | Unknown | National Institute of Allergy and Infectious Diseases (NIAID) | 13 | 2012-04-01 | 2019-12-04 |
Anemia, Aplastic (2) · Lymphoma (2) · Myelodysplastic Syndromes (2) · X-Linked Combined Immunodeficiency Diseases (2) · Acquired Immunodeficiency Syndrome (1) · Anemia, Diamond-Blackfan (1) · Anemia, Sickle Cell (1) · Ataxia Telangiectasia (1) · Bone Marrow Failure Disorders (1) · Graft vs Host Disease (1) · Hemoglobinopathies (1) · Histiocytosis (1) · Histiocytosis, Langerhans-Cell (1) · Leukemia (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Genetic Diseases, Inborn (7) · Immune System Diseases (7) · Immunologic Deficiency Syndromes (7) · Infant, Newborn, Diseases (3) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Anemia (2) · Bone Marrow Diseases (2) · DNA Repair-Deficiency Disorders (2) · Genetic Diseases, X-Linked (2) · Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Immunoproliferative Disorders (2)
Busulfan (2) · Alemtuzumab (1) · Cyclophosphamide (1) · Fibroblast Growth Factor 7 (1) · Gadolinium (1) · Gadolinium DTPA (1) · Immunoglobulins, Intravenous (1) · Melphalan (1) · Methylprednisolone (1) · Methylprednisolone Hemisuccinate (1) · Tacrolimus (1) · Thiotepa (1) · fludarabine (1) · fludarabine phosphate (1)
ASIS Corporation (1) · Diane George (1) · Grace Therapeutics Inc. (1) · Great Ormond Street Hospital for Children NHS Foundation Trust (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Taiga Biotechnologies, Inc. (1) · University College, London (1)
United States (3) · United Kingdom (2) · Canada (1) · Israel (1)
Adrian Thrasher, Prof (1) · Claire Booth, Dr (1) · Diane George, MD (1) · Hanh Nguyen, MD (1) · Janice Faulknor, MD (1) · Li Nguyen, MD (1) · Suk See DeRavin, M.D., Ph.D (1) · Thanh Phung, MD (1)