6 completed, 2 not yet recruiting, 2 recruiting, 1 active not recruiting. 5 Not applicable, 3 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Not yet recruiting 2, Active not recruiting 1, Completed 1, Recruiting 1 |
| Phase 3 | 3 | Completed 3 |
| Phase 2 | 1 | Recruiting 1 |
Follow Post-Stroke Spasticity: new trials by email Literature Review of Post-Stroke Spasticity trials Research Report on Post-Stroke Spasticity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study) Administration of BMS-986368, Placebo - Post-Stroke Spasticity | Phase 2 | Recruiting | Alberto Esquenazi | 42 | 2026-09-02 | 2026-10-01 |
| Extracorporeal Shock Wave Therapy in Botulinum Toxin-Treated Patients With Post-Stroke Ankle Plantar Flexor Spasticity Radial Extracorporeal Shock Wave Therapy (rESWT), Conventional Physical Therapy and Rehabilitation - Stroke, Post-stroke Spasticity of the Lower Limb | Not applicable | Not yet recruiting | Pamukkale University | 32 | 2026-07-20 | 2026-07-10 |
| Effect of NMES on Spasticity Neuromuscular electrical stimulation (NMES) - Post-Stroke Spasticity | Not applicable | Not yet recruiting | Izmir Katip Celebi University | 4 | 2026-06-15 | 2026-06-03 |
| ESTIM-UL: FES for Upper Limb Recovery After Stroke Functional Electrical Stimulation (FES), Conventional Rehabilitation - Stroke, Post-Stroke Spasticity | Not applicable | Recruiting | University of Foggia | 40 | 2026-05-01 | 2026-09-22 |
| Effect of Extracorporeal Shock Wave Therapy on Spasticity and Mobility in Stroke Patients Extracorporeal Shock Wave Therapy (ESWT), Sham Extracorporeal Shock Wave Therapy - Stroke, Post-Stroke Spasticity | Not applicable | Completed | Istanbul Medipol University Hospital | 85 | 2026-04-10 | 2026-10-28 |
| Efficacy of Focused Shock Wave Therapy Before and After Botulinum Toxin Injection in Patients With Post-Stroke Spastic Equinus/Equinovarus Foot: A Randomized Clinical Trial Botulinum toxin type A, Focal Extracorporeal Shock Wave Therapy (ESWT) - Post-Stroke Spasticity, Spastic Equinovarus Foot | Not applicable | Active not recruiting | María Belén Martínez Luna | 69 | 2024-10-10 | 2026-08-11 |
| Validity and Inter-rater Reliability for Early Recognition of Spasticity Using the Decision Tree Tool Post-stroke Spasticity | Completed | Merz Therapeutics GmbH | 70 | 2023-10-27 | 2026-05-22 | |
| Pain During Injection With Botulinum Toxin in Post-stroke Spasticity Treatment pain rating during injection with botulinum toxin - Post-stroke Spasticity | Completed | University Hospital, Grenoble | 46 | 2012-03-01 | 2017-08-16 | |
| Dysport® Adult Lower Limb Spasticity Follow-on Study Botulinum toxin type A - Post-stroke Spasticity, Spasticity Post-Traumatic Brain Injury | Phase 3 | Completed | Ipsen | 352 | 2011-06-01 | 2022-09-28 |
| Study Of GSK1358820 In Patients With Post-Stroke Upper Limb Spasticity GSK1358820, Placebo - Post-Stroke Spasticity, Cerebrovascular Accident | Phase 3 | Completed | GlaxoSmithKline | 109 | 2007-05-01 | 2017-05-30 |
| Study of GSK1358820 In Patients With Post-Stroke Lower Limb Spasticity GSK1358820, Placebo - Post-Stroke Spasticity, Cerebrovascular Accident | Phase 3 | Completed | GlaxoSmithKline | 120 | 2007-05-01 | 2010-09-08 |
Stroke (8) · Muscle Spasticity (7) · Nervous System Diseases (1) · Pain (1)
Brain Diseases (8) · Cardiovascular Diseases (8) · Central Nervous System Diseases (8) · Cerebrovascular Disorders (8) · Vascular Diseases (8) · Muscle Hypertonia (7) · Muscular Diseases (7) · Musculoskeletal Diseases (7) · Nervous System Diseases (7) · Neurologic Manifestations (7) · Neuromuscular Manifestations (7) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7)
Botulinum Toxins, Type A (2) · Botulinum Toxins (1) · Extracorporeal Shockwave Therapy (1) · Rehabilitation (1) · abobotulinumtoxinA (1)
GlaxoSmithKline (2) · Alberto Esquenazi (1) · Ipsen (1) · Istanbul Medipol University Hospital (1) · Izmir Katip Celebi University (1) · María Belén Martínez Luna (1) · Merz Therapeutics GmbH (1) · Pamukkale University (1) · University Hospital, Grenoble (1) · University of Foggia (1)
Turkey (Türkiye) (3) · Italy (2) · Japan (2) · United States (2) · Australia (1) · Austria (1) · Belgium (1) · Czechia (1) · France (1) · Hungary (1) · Poland (1) · Portugal (1) · Russia (1) · Slovakia (1) · Spain (1)
PMID 20358216, PMID 20569068, PMID 29093068, PMID 31529136, PMID 32108436, PMID 32741133, PMID 42211298
2009 (1)