3 completed, 3 recruiting, 3 unknown, 1 not yet recruiting. 10 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 10 | Completed 3, Recruiting 3, Unknown 3, Not yet recruiting 1 |
Follow Pleural Diseases: new trials by email Literature Review of Pleural Diseases trials Research Report on Pleural Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of the Feasibility and Efficacy of PrednisonE for Non-specifiC pleuriTis Corticosteroid, No Corticosteroid - Pleuritis, Non-specific | Early Phase 1 | Recruiting | Icahn School of Medicine at Mount Sinai | 40 | 2025-05-29 | 2026-06-25 |
| The Outcome of Inserting Intercostal Tube or Pleurodesis for Malignant Pleural Effusion Intercostal chest tube, Pleurodesis - Malignant Pleural Effusions (Mpe) | Early Phase 1 | Not yet recruiting | Assiut University | 20 | 2024-12-30 | 2024-12-19 |
| Safety and Efficacy of NK510 to Treat NSCLC NK510, Tislelizumab，atezolizumab or sugemalimab, systemic therapy as selected by the investigator - NSCLC | Early Phase 1 | Recruiting | Base Therapeutics (Shanghai) Co., Ltd. | 12 | 2023-07-01 | 2026-09-09 |
| Dual-targeting HER2 and PD-L1 CAR-T for Solid Tumors Dual-targeting HER2 and PD-L1 CAR-T cells - Peritoneal Carcinoma Metastatic, Pleural Effusion, Malignant | Early Phase 1 | Recruiting | Sichuan University | 18 | 2021-03-12 | 2024-10-30 |
| Safety and Efficacy Study of Virus Activated Killer Immune Cells (VAK) for Malignant Pleural and Peritoneal Effusion Virus Activated Killer immune Cells, Saline - Malignant Pleural Effusion, Malignant Peritoneal Effusion | Early Phase 1 | Unknown | Sheng Hu | 90 | 2020-07-24 | 2022-10-04 |
| Octreotide Improves Human Lymphatic Fluid Transport a Translational Trial Octreotide infusion, Saline infusion - Lymphatic Diseases, Chylothorax | Early Phase 1 | Completed | Copenhagen University Hospital, Rigshospitalet | 16 | 2020-07-01 | 2023-03-30 |
| Management of Malignant Pleural Effusion - Indwelling Pleural Catheter or Talc Pleurodesis Talc Pleurodesis, Indwelling Pleural Catheter, chest ultrasound - Pleural Effusion, Malignant, Lung Neoplasms | Early Phase 1 | Unknown | Rambam Health Care Campus | 120 | 2016-08-01 | 2016-07-07 |
| Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma Adoptive Transfer of re-directed T cells - Malignant Pleural Mesothelioma | Early Phase 1 | Completed | University of Zurich | 4 | 2015-02-19 | 2019-08-07 |
| Pleural Cryobiopsies During Semirigid Thoracoscopy: A New Technique Cryobiopsy (Autoclavable cryoprobe 20416-032) - Pleural Effusion, Pleural Diseases | Early Phase 1 | Completed | The University Clinic of Pulmonary and Allergic Diseases Golnik | 15 | 2010-02-01 | 2013-12-05 |
| Study Designed to Optimize the Treatment of Primary Pneumothorax VATS bullectomy and mechanical pleuradesis., Chest tube insertion, Epidural - Primary Spontaneous Pneumothorax, Pleural Disease | Early Phase 1 | Unknown | Odense University Hospital | 300 | 2009-03-01 | 2016-08-16 |
Pleural Effusion, Malignant (5) · Pleural Effusion (2) · Chylothorax (1) · Lung Neoplasms (1) · Lymphatic Diseases (1) · Mesothelioma, Malignant (1) · Myeloproliferative Disorder, Chronic, with Eosinophilia (1) · Pleurisy (1) · Pneumothorax (1)
Respiratory Tract Diseases (10) · Neoplasms (6) · Neoplasms by Site (6) · Pleural Neoplasms (6) · Respiratory Tract Neoplasms (6) · Thoracic Neoplasms (6) · Pleural Effusion (5) · Lung Diseases (2) · Adenoma (1) · Hemic and Lymphatic Diseases (1) · Infections (1) · Lung Neoplasms (1) · Mesothelioma (1) · Neoplasms by Histologic Type (1)
Adrenal Cortex Hormones (1) · Anesthesia, Local (1) · Chest Tubes (1) · Injections, Epidural (1) · Lidocaine (1) · Pleurodesis (1) · Prednisone (1) · Sodium Chloride (1) · sugemalimab (1)
Assiut University (1) · Base Therapeutics (Shanghai) Co., Ltd. (1) · Copenhagen University Hospital, Rigshospitalet (1) · Icahn School of Medicine at Mount Sinai (1) · Odense University Hospital (1) · Rambam Health Care Campus (1) · Sheng Hu (1) · Sichuan University (1) · The University Clinic of Pulmonary and Allergic Diseases Golnik (1) · University of Zurich (1)
China (3) · Denmark (2) · Egypt (1) · Slovenia (1) · Switzerland (1) · United States (1)
Ales Rozman, MD (1) · Alessandra Curioni, MD (1) · Tangfeng Lv, PhD (1) · Udit Chaddha, MBBS (1) · Winnie Hedevang Olesen, ph.d.student (1)
PMID 29509892, PMID 31525813, PMID 31804680, PMID 33222091, PMID 36402752