7 completed, 2 unknown, 2 withdrawn. 6 Phase 2, 3 Not applicable, 2 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Unknown 1, Withdrawn 1 |
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 1 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Withdrawn 1 |
Follow Platelet Dysfunction Due to Drugs: new trials by email Literature Review of Platelet Dysfunction Due to Drugs trials Research Report on Platelet Dysfunction Due to Drugs
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Aspirin Resistance in Trinidad. Aspirin 81Mg Ec Tab - Platelet Dysfunction Due to Drugs | Phase 2 | Completed | The University of The West Indies | 48 | 2024-01-15 | 2025-09-12 |
| The Effect of empagliFlozin on Platelet Function profilEs in diabetiC patienTs - The EFFECT Study. SGLT2 inhibitor - Platelet Dysfunction Due to Drugs | Phase 2 / Phase 3 | Completed | The University of The West Indies | 25 | 2020-01-01 | 2024-09-03 |
| The Effects of loW Dose tIcagrelor on Platelet Function Testing in Patients With Stable Coronary arTery Disease Ticagrelor - Platelet Dysfunction Due to Drugs | Phase 1 / Phase 2 | Completed | The University of The West Indies | 25 | 2019-10-01 | 2020-05-21 |
| Reversal of Dual Antiplatelet Therapy With Cold Stored Platelets Autologous Platelet Transfusion (room-temperature-stored), Autologous Platelet Transfusion (cold-stored 5 days), Autologous Platelet Transfusion (cold-stored 10 days) - Bleeding, Platelet Dysfunction Due to Drugs | Phase 1 / Phase 2 | Unknown | Bloodworks | 60 | 2018-12-03 | 2020-07-14 |
| Platelet Function With Various Storage Techniques Infusion of Platelets, Placebo - Platelet Dysfunction Due to Drugs | Phase 2 | Withdrawn | Northwell Health | 2018-07-15 | 2019-05-29 | |
| Trimetazidine as an Adjunct to Enhance Clopidogrel Response. Trimetazidine - Platelet Dysfunction Due to Drugs | Phase 2 | Completed | The University of The West Indies | 24 | 2018-07-01 | 2019-12-02 |
| PLATelet Function Operating Room Monitoring Platelet function test - Platelet Dysfunction Due to Drugs, Bleeding | Completed | IRCCS Policlinico S. Donato | 490 | 2017-02-01 | 2020-06-22 | |
| Study of AggreGuide A-100 (ADP) Assay P2Y12 inhibitor, Platelet function test - Risk Factor, Cardiovascular, Platelet Dysfunction Due to Drugs | Not applicable | Completed | Aggredyne, Inc. | 280 | 2017-01-09 | 2019-02-21 |
| Reversal of the Antiplatelet Effects of Ticagrelor in Combination With Aspirin, Using Normal Platelets Antiplatelet treatment - Ticagrelor, Aspirin | Not applicable | Unknown | Hamilton Health Sciences Corporation | 10 | 2017-01-01 | 2017-04-06 |
| Preoperative Dual Antiplatelet Therapy: Platelet Function and Influence of Cardiopulmonary Bypass CPB Low Dose, CPB High Dose - Cardiopulmonary Bypass, Platelet Disorder | Not applicable | Completed | Umeå University | 60 | 2016-11-01 | 2018-03-29 |
| The IDEAL-PCI Extended Registry DAPT reduction, DAPT on-target, DAPT intensification - Coronary Arterioscleroses, Platelet Dysfunction Due to Drugs | Phase 4 | Withdrawn | Kaiser Franz Josef Hospital | 2018-01-26 |
Hemorrhage (2) · Blood Platelet Disorders (1) · Coronary Artery Disease (1) · Hemostatic Disorders (1)
Cardiovascular Diseases (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Vascular Diseases (2) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Coronary Disease (1) · Heart Diseases (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Hemorrhagic Disorders (1) · Myocardial Ischemia (1)
Aspirin (3) · Ticagrelor (3) · Clopidogrel (2) · Platelet Function Tests (2) · Prasugrel Hydrochloride (1) · Sodium Chloride (1) · Sodium-Glucose Transporter 2 Inhibitors (1) · Trimetazidine (1) · empagliflozin (1)
The University of The West Indies (4) · Aggredyne, Inc. (1) · Bloodworks (1) · Hamilton Health Sciences Corporation (1) · IRCCS Policlinico S. Donato (1) · Kaiser Franz Josef Hospital (1) · Northwell Health (1) · Umeå University (1)
Trinidad and Tobago (4) · Austria (1) · Canada (1) · Italy (1) · Sweden (1) · United States (1)
Guenter Christ, MD (1) · Marco Ranucci, MD (1) · Moritz Stolla, MD (1) · Phil Speros (1)
PMID 31292901, PMID 32766961, PMID 33306161, PMID 34143384, PMID 34478498, PMID 39008026