15 completed, 13 unknown, 10 recruiting, 7 not yet recruiting. 24 Phase 2, 15 Phase 1, 9 Not applicable, 4 Phase 3.
Follow Peritoneal Metastases: new trials by email Literature Review of Peritoneal Metastases trials Research Report on Peritoneal Metastases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MRI-Guided Adaptive Radiotherapy for Limited Peritoneal Metastases (MARACAS Trial). MRI-guided stereotactic body radiotherapy - Peritoneal Carcinomatosis, Oligometastatic Disease | Phase 2 | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 34 | 2026-07-01 | 2026-05-18 |
| Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial") Cyclophosphamide, Fludarabine, Cetuximab - Colorectal Cancer, Peritoneal Metastases | Phase 1 / Phase 2 | Recruiting | M.D. Anderson Cancer Center | 28 | 2026-04-20 | 2026-10-05 |
| Impact of an Omega-3 Enriched Oral Nutritional Supplement on Improving Surgical Outcomes in Patients With Peritoneal Carcinomatosis Undergoing Cytoreductive Surgery ONS enriched with Omega-3, Standard ONS - Peritoneal Carcinosis, Peritoneal Metastases | Not applicable | Not yet recruiting | Catholic University of the Sacred Heart | 28 | 2026-04-01 | 2026-03-17 |
| A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis Mass-based response testing (MRT) - Appendiceal Cancer, Colorectal Adenocarcinoma | Not applicable | Recruiting | Yale University | 20 | 2026-02-17 | 2026-07-21 |
| Intra-tumoral (IT) Injection of vvDD-hIL2-2-RG-1 for Metastatic Gastrointestinal and Peritoneal Tumors vvDD-hIL-2-RG-1 - Gastric Neoplasms, Esophageal Cancer | Phase 1 | Recruiting | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 18 | 2025-05-06 | 2025-06-03 |
| Systemic Application of Cadonilimab, LM-302, and S-1 Combined With Intraperitoneal Infusion of Paclitaxel for the Treatment of Claudin 18.2-positive Gastric Cancer With Peritoneal Metastasis Cadonilimab, LM-302, S-1, paclitaxel - Gastric Cancer Stage IV, Peritoneal Metastases | Phase 2 | Recruiting | Ruijin Hospital | 40 | 2025-02-25 | 2026-07-29 |
| The Efficacy of PIPAC and Minimally Invasive Radical Resection in High-risk Gastric Cancer Patients. Cisplatin, Doxorubicin - Gastric Cancer, Chemotherapy, Adjuvant | Phase 2 | Not yet recruiting | Odense University Hospital | 264 | 2024-09-01 | 2024-03-06 |
| The PIPAC-OPC7 Study: The Use of PET/CT Scans as a Method of Evaluation in Patients Treated With PIPAC, a Pilot Study. scan - Peritoneal Cancer, Peritoneal Metastases | Completed | Odense University Hospital | 34 | 2024-03-15 | 2026-03-16 | |
| HIPEC Combined With SOX and Sintilimab in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis S-1, Oxaliplatin sintilimab HIPEC - Peritoneal Metastases, Gastric Cancer | Phase 2 | Not yet recruiting | Sichuan University | 69 | 2024-02-20 | 2024-01-19 |
| Development and Validation of a PSN-AI Prediction Model Analyse pathologic slides - Colorectal Cancer, Peritoneal Metastases | Unknown | Sixth Affiliated Hospital, Sun Yat-sen University | 50 | 2024-02-01 | 2024-01-30 | |
| Role of PET/CT in Peritoneal Deposits Assessment PET/CT - Peritoneal Metastases | Unknown | Aya Khaled Mahmoud | 50 | 2024-01-01 | 2023-11-18 | |
| Intraperitoneal LSTA1 in CRS-HIPEC CRS-HIPEC + LSTA1, CRS-HIPEC alone - Colorectal Cancer, Ovarian Carcinoma | Phase 1 | Withdrawn | University of California, San Diego | 2023-11-30 | 2024-08-20 | |
| Neoadjuvant Systemic and Peritoneal Chemotherapy for Advanced Gastric Cancer Doxorubicin and Cisplatin - Gastric Cancer, Peritoneal Metastases | Phase 2 | Not yet recruiting | Imperial College London | 20 | 2023-11-01 | 2023-09-13 |
| A Prospective Multicentre Clinical Study of Dynamic Monitoring of Plasma ctDNA Methylation Markers to Predict Recurrence of Colorectal Cancer After Complete Resection of Peritoneal Metastases As an observational study, we did not intervene - Colorectal Cancer, Peritoneal Metastases | Recruiting | Fudan University | 50 | 2023-10-01 | 2025-03-30 | |
| The Application of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) for Peritoneal Surface Malignancies Pressured Intraperitoneal Aerosol Chemotherapy - Peritoneal Metastases | Phase 2 | Recruiting | The University of Hong Kong | 60 | 2023-09-01 | 2026-04-30 |
| On-treatment Biomarkers in Metastatic Colorectal Cancer for Life Chemotherapy, Resection of the primary tumor, Resection of tumour metastases - Metastatic Colorectal Cancer, Chemotherapy Effect | Recruiting | Region Skane | 100 | 2023-03-01 | 2025-07-17 | |
| Sintilimab in Combination With S-1/Oxaliplatin With Nab-paclitaxel Intraperitoneal Infusion for Untreated Advanced Gastric Cancer With Malignant Ascites Sintilimab in Combination With S-1/oxaliplatin With nab-paclitaxel intraperitoneal infusion, Blood samples, tumor biopsy specimens, ascites, and feces samples will be collected - Gastric Cancer, Peritoneal Metastases | Phase 2 | Unknown | Zhejiang Cancer Hospital | 35 | 2023-03-01 | 2023-09-21 |
| Hyperthermic Intraperitoneal Treatment of rmhTNF for CRCPM: Phase II Clinical Trial Hyperthermic intraperitoneal treatment of recombinant modified human tumor necrosis factor (rmhTNF) - Peritoneal Metastases, Colorectal Cancer | Phase 2 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 10 | 2023-02-10 | 2023-03-06 |
| HIPEC Combined Gastrectomy in Patients With Advanced Gastric Cancer Received Neoadjuvant Chemotherapy HIPEC - Gastric Cancer, Peritoneal Metastases | Phase 2 / Phase 3 | Not yet recruiting | Zhixin Cao | 200 | 2023-01-01 | 2022-12-06 |
| Prediction of Peritoneal Metastasis for Gastric Cancer Based on Radiomics Peritoneal metastasis status ascertainment - Gastric Cancer, Peritoneal Metastases | Recruiting | Chinese Academy of Sciences | 400 | 2023-01-01 | 2023-02-14 |
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Colorectal Neoplasms (18) · Stomach Neoplasms (18) · Peritoneal Neoplasms (13) · Appendiceal Neoplasms (4) · Colonic Neoplasms (4) · Carcinoma (3) · Neoplasms (3) · Ovarian Neoplasms (3) · Pancreatic Neoplasms (3) · Ascites (1) · Bile Duct Neoplasms (1) · Breast Neoplasms (1) · COVID-19 (1) · Cholangiocarcinoma (1) · Colorectal Cancer, Hereditary Nonpolyposis, Type 6 (1)
Neoplasms by Site (44) · Neoplasms (43) · Digestive System Diseases (42) · Digestive System Neoplasms (42) · Gastrointestinal Diseases (38) · Gastrointestinal Neoplasms (37) · Intestinal Diseases (21) · Colonic Diseases (20) · Intestinal Neoplasms (20) · Rectal Diseases (18) · Stomach Diseases (18) · Abdominal Neoplasms (13) · Peritoneal Diseases (13) · Endocrine Gland Neoplasms (6) · Endocrine System Diseases (6)
Oxaliplatin (6) · Hyperthermic Intraperitoneal Chemotherapy (4) · Paclitaxel (4) · Cisplatin (3) · Doxorubicin (3) · Irinotecan (3) · S 1 (combination) (3) · Cytoreduction Surgical Procedures (2) · Drug Therapy (2) · Fluorouracil (2) · sintilimab (2) · Bevacizumab (1) · Blood Specimen Collection (1) · Capecitabine (1) · Cetuximab (1)
Laval University (3) · National Cancer Centre, Singapore (3) · Uppsala University (3) · Enlivex Therapeutics RDO Ltd. (2) · Imperial College London (2) · Michael Bau Mortensen (2) · Odense University Hospital (2) · Ruijin Hospital (2) · Sixth Affiliated Hospital, Sun Yat-sen University (2) · University Hospital, Ghent (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) (1) · Aya Khaled Mahmoud (1) · Capital Medical University (1) · Catharina Ziekenhuis Eindhoven (1)
China (11) · United States (7) · Denmark (5) · Netherlands (4) · Sweden (4) · Belgium (3) · Canada (3) · Italy (3) · Singapore (3) · United Kingdom (3) · Israel (2) · South Korea (2) · France (1) · Germany (1) · Hong Kong (1)
Alexandre Brind'Amour, MD (3) · Alexandra R Brandt-Kerkhof, MD (1) · Andrew G Renehan, PhD (1) · Anne-Mette Hvas, MD, PhD (1) · Arend G Aalbers, MD (1) · Avi Nissan, MD (1) · Claramae Chia, MBBS (1) · Cornelis J Punt, MD, PhD (1) · Eino B van Duyn, MD, PhD (1) · George B Hanna, FRCS, PhD (1) · Grace Tan, MD (1) · Guoxiang Cai (1) · Ignace H de Hingh, MD, PhD (1) · Jakob Eberhard, M.D. PhD. (1)
PMID 14551293, PMID 19782876, PMID 21246515, PMID 21865109, PMID 29321007, PMID 30689702, PMID 30911655, PMID 30911656, PMID 30911669, PMID 31023318, PMID 33398064, PMID 33528867, PMID 34009291, PMID 37212686, PMID 38238055, PMID 41542221, PMID 42372745
2016 (1)