48 completed, 26 recruiting, 19 unknown, 12 terminated. 48 Phase 2, 29 Phase 1, 26 Not applicable, 6 Phase 3, 2 Early Phase 1.
Follow Peritoneal Carcinomatosis: new trials by email Literature Review of Peritoneal Carcinomatosis trials Research Report on Peritoneal Carcinomatosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Paricalcitol Versus Pirfenidone for Improving Surgical Resectability in Patients With Peritoneal Cancer Paricalcitol, pirfenidone - Peritoneal (Metastatic) Cancer, Peritoneal Carcinoma | Phase 2 | Not yet recruiting | Patrick Wagner, MD, FACS | 74 | 2026-09-01 | 2026-10-05 |
| Safety and Efficacy of PIPAC Using Single Agent Mitomycin in Solid Tumors Mitomycin C (MMC), Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) - Peritoneal Carcinomatosis | Phase 1 | Recruiting | H. Lee Moffitt Cancer Center and Research Institute | 24 | 2026-08-05 | 2026-09-16 |
| MRI-Guided Adaptive Radiotherapy for Limited Peritoneal Metastases (MARACAS Trial). MRI-guided stereotactic body radiotherapy - Peritoneal Carcinomatosis, Oligometastatic Disease | Phase 2 | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 34 | 2026-07-01 | 2026-05-18 |
| Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC) Modified early post-operative intraperitoneal chemotherapy (mEPIC) - Peritoneal Carcinomatosis, Appendiceal Neoplasms | Phase 2 | Recruiting | Ciusss de L'Est de l'Île de Montréal | 25 | 2026-05-01 | 2026-05-14 |
| Heated Versus Aerosol-based Laparoscopic Chemotherapy for Cancer That Has Spread to the Peritoneum (Abdominal Lining) Heated intra-peritoneal chemotherapy, Aerosolized intra-peritoneal chemotherapy - Peritoneal (Metastatic) Cancer, Peritoneal Carcinomatosis | Phase 2 | Recruiting | Patrick Wagner, MD, FACS | 200 | 2026-01-05 | 2026-02-27 |
| Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity Standard of Care Chemotherapy, Biospecimen Collection, Computed Tomography - Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma | Phase 2 / Phase 3 | Recruiting | ECOG-ACRIN Cancer Research Group | 148 | 2025-10-24 | 2026-10-05 |
| Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer Cisplatin, Mitomycin - Gastric Cancer, Peritoneal Carcinomatosis | Phase 2 | Recruiting | University of Chicago | 21 | 2025-09-09 | 2026-09-08 |
| Blood Clearance Kinetics of the Nucleosome and CTCF in Peritoneal Metastasis Colorectal Cancer. Blood sampling - Peritoneal Carcinomatosis, Peritoneal Metastases From Colorectal Cancer | Not applicable | Recruiting | Hospices Civils de Lyon | 58 | 2025-05-06 | 2026-02-13 |
| Intensification Treatment of Ovarian Cancer by PIPAC PIPAC - Advanced Epithelial Ovarian Cancer, Peritoneal Carcinomatosis | Phase 2 | Recruiting | Moscow Regional Oncological Dispensary | 160 | 2025-04-02 | 2026-04-07 |
| Enhanced Recovery After Surgery (ERAS) in Patients With Peritoneal Carcinomatosis Undergoing Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC) ERAS Perioperative Management Protocol - Peritoneal Carcinomatosis | Not applicable | Recruiting | Fondazione del Piemonte per l'Oncologia | 300 | 2025-01-23 | 2026-04-03 |
| PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis Pafolacianine (CYTALUX) with intraoperative fluorescent near-infrared (NIR) imaging - Gastrointestinal Cancer, Peritoneal Carcinomatosis | Early Phase 1 | Recruiting | University of California, Irvine | 10 | 2024-11-13 | 2026-02-27 |
| A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer or Malignant Peritoneal Mesothelioma M28z1XXPD1DNR CAR - Mesothelin Positive, Mesothelin-Expressing Tumors | Phase 1 | Recruiting | Memorial Sloan Kettering Cancer Center | 32 | 2024-09-30 | 2026-10-15 |
| Molecular Citology to Detect Free Cancer Cells in Peritoneal Fluid Peritoneal Carcinomatosis | Completed | University of Campania Luigi Vanvitelli | 108 | 2024-07-01 | 2026-03-20 | |
| A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery Radspherin - Peritoneal Carcinomatosis, Ovarian Cancer | Phase 2 | Recruiting | Oncoinvent Solutions AS | 114 | 2024-06-15 | 2026-05-20 |
| The PIPAC-OPC7 Study: The Use of PET/CT Scans as a Method of Evaluation in Patients Treated With PIPAC, a Pilot Study. scan - Peritoneal Cancer, Peritoneal Metastases | Completed | Odense University Hospital | 34 | 2024-03-15 | 2026-03-16 | |
| Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) and Electrostatic PIPAC (ePIPAC) With Paclitaxel In Patients With Peritoneal Carcinomatosis Paclitaxel - Peritoneal Carcinomatosis | Phase 1 | Unknown | National University Hospital, Singapore | 36 | 2023-08-04 | 2024-05-29 |
| Galunisertib Combined With Capecitabine in Advanced CRC With PM Galunisertib plus capecitabine - Colorectal Cancer Metastatic, Peritoneal Carcinomatosis | Phase 1 / Phase 2 | Active not recruiting | The Netherlands Cancer Institute | 31 | 2023-07-28 | 2026-07-13 |
| Ga68-FAPI-46 PET/CT for Preoperative Assessment of Peritoneal Carcinomatosis FAPI PET/CT - Cancer, Peritoneal Carcinomatosis | Not applicable | Recruiting | Jules Bordet Institute | 80 | 2023-05-30 | 2025-03-31 |
| Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis Biospecimen Collection (Blood, Ascites/Peritoneal Wash Fluid and/or Tumor Samples) - Peritoneal Carcinomatosis, Gastrointestinal Peritoneal Carcinomatosis | Not applicable | Recruiting | University of California, Irvine | 20 | 2023-05-04 | 2026-08-14 |
| Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma. Indocyanine green - Gastric Cancer, Gastric Adenocarcinoma | Phase 2 | Terminated | Laval University | 11 | 2022-12-15 | 2024-04-02 |
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Peritoneal Neoplasms (121) · Stomach Neoplasms (30) · Colorectal Neoplasms (24) · Ovarian Neoplasms (19) · Appendiceal Neoplasms (11) · Neoplasms (11) · Colonic Neoplasms (10) · Pancreatic Neoplasms (7) · Carcinoma (6) · Fallopian Tube Neoplasms (6) · Pseudomyxoma Peritonei (6) · Breast Neoplasms (5) · Gastrointestinal Neoplasms (4) · Neoplasm Metastasis (4) · Carcinoma, Ovarian Epithelial (3)
Abdominal Neoplasms (121) · Digestive System Diseases (121) · Neoplasms by Site (121) · Digestive System Neoplasms (120) · Peritoneal Diseases (120) · Neoplasms (110) · Gastrointestinal Diseases (56) · Gastrointestinal Neoplasms (52) · Intestinal Diseases (31) · Colonic Diseases (30) · Intestinal Neoplasms (30) · Stomach Diseases (30) · Endocrine System Diseases (28) · Endocrine Gland Neoplasms (27) · Rectal Diseases (24)
Hyperthermic Intraperitoneal Chemotherapy (15) · Cisplatin (13) · Oxaliplatin (10) · Cytoreduction Surgical Procedures (9) · Paclitaxel (9) · Fluorouracil (7) · Mitomycin (7) · Doxorubicin (6) · Leucovorin (4) · Blood Specimen Collection (3) · Docetaxel (3) · Laparoscopy (3) · sodium thiosulfate (3) · 1,2-diaminocyclohexaneplatinum II citrate (2) · Capecitabine (2)
National Cancer Institute (NCI) (6) · Hospices Civils de Lyon (4) · University Hospital, Ghent (4) · Institut du Cancer de Montpellier - Val d'Aurelle (3) · Jules Bordet Institute (3) · Laval University (3) · M.D. Anderson Cancer Center (3) · The Netherlands Cancer Institute (3) · University of California, Irvine (3) · CHU de Reims (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · Fondazione del Piemonte per l'Oncologia (2) · Koen Rovers (2) · Maimónides Biomedical Research Institute of Córdoba (2) · Michael Bau Mortensen (2)
United States (32) · Belgium (13) · France (13) · Germany (9) · Netherlands (8) · China (7) · Italy (7) · Canada (6) · Spain (6) · Denmark (4) · Norway (2) · Russia (2) · Singapore (2) · South Korea (2) · Sweden (2)
Alexandre Brind'Amour, MD (3) · Andrew M Blakely, M.D. (2) · Brian D Badgwell (2) · Gabriel Liberale, MD (2) · Maheswari Senthil, MD (2) · Patrick Wagner, MD (2) · Wim P Ceelen, MD, PhD, Prof (2) · Agnieszka Michael (1) · Alexander Zakharenko, PhD (1) · Alexandra R Brandt-Kerkhof, MD (1) · Alexey S. Dzasokhov, MD, PhD (1) · Alvaro Arjona-Sanchez, PhD (1) · Amir A Jazaeri (1) · Andre Roncon Dias, MD, PhD (1)
PMID 20500867, PMID 20525328, PMID 23377563, PMID 23765417, PMID 24006094, PMID 24275155, PMID 24447964, PMID 26681640, PMID 27520560, PMID 29149865, PMID 29773661, PMID 29899763, PMID 30131226, PMID 30463745, PMID 30607301, PMID 30755498, PMID 30911655, PMID 30911663, PMID 31023318, PMID 31060544, PMID 31084544, PMID 31352425, PMID 31469058, PMID 32556731, PMID 32572849, PMID 32594200, PMID 32738543, PMID 33528867, PMID 33544279, PMID 33902498, PMID 34009291, PMID 34070561, PMID 34757489, PMID 35549912, PMID 35551444, PMID 35843174, PMID 36410913, PMID 36513815, PMID 36604127, PMID 36795510, PMID 36870941, PMID 37124504, PMID 37227734, PMID 37460370, PMID 37580610, PMID 37875869, PMID 37916797, PMID 37993560, PMID 38471508, PMID 39288528
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