56 completed. 56 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 56 | Completed 56 |
Follow Overactive Bladder: new trials by email Literature Review of Overactive Bladder trials Research Report on Overactive Bladder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Vaginal 17β-Estradiol on the Urinary Storage Symptoms in Postmenopausal Women vaginal 17 beta-estradiol, Placebo, Behavioral modifications - Lower Urinary Tract Symptoms, Female Genitourinary Disease | Phase 4 | Completed | Mahidol University | 86 | 2024-04-08 | 2025-04-20 |
| Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection Single-Dose Antibiotic, Multi-Dose Antibiotic - Overactive Bladder, Overactive Bladder Syndrome | Phase 4 | Completed | The Cleveland Clinic | 100 | 2022-12-06 | 2024-01-02 |
| Procedural Discomfort Related to Number of Intradetrusor Botox Injections Intradetrusor Botox Injections - Overactive Bladder | Phase 4 | Completed | The Methodist Hospital Research Institute | 108 | 2022-07-07 | 2025-04-13 |
| Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial OnabotulinumtoxinA 100 UNT [Botox] - Overactive Bladder, Urinary Urge Incontinence | Phase 4 | Completed | University of California, Irvine | 116 | 2022-05-01 | 2026-02-25 |
| Posterior Tibial Nerve Stimulation (PTNS) Plus Mirabegron to Treat Refractory OAB Symptoms (PTNS-M Study) Mirabegron 50 MG, Posterior Tibial Nerve Stimulation (PTNS) - Overactive Bladder | Phase 4 | Completed | University of Alabama at Birmingham | 54 | 2021-10-01 | 2023-07-20 |
| Minimizing Pain During Office Intradetrussor Botox Injection Bicarbonate protocol, Standard protocol - Overactive Bladder, Overactive Detrusor | Phase 4 | Completed | Boston Urogynecology Associates | 85 | 2020-08-15 | 2025-03-06 |
| Tolterodine Relieves Overactive Bladder Symptoms in Women With Moderate-to-severe Obstructive Sleep Apnea Syndrome Tolterodine Tartrate 4 MG, Continuous positive airway pressure therapy (CPAP) - Overactive Bladder, Obstructive Sleep Apnea | Phase 4 | Completed | Yuzuncu Yil University | 60 | 2020-06-01 | 2022-02-22 |
| Is 10 Injections of Bladder Botox Less Painful Than 20 Injections? OnabotulinumtoxinA 100 Units - Overactive Bladder | Phase 4 | Completed | Wake Forest University Health Sciences | 41 | 2019-11-10 | 2024-04-17 |
| Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder Anticholinergic, Beta-3 Agonists, Adrenergic, Functional magnetic resonance imaging (fMRI) - Overactive Bladder, Dementia | Phase 4 | Completed | Baylor Research Institute | 12 | 2019-08-05 | 2024-02-02 |
| Evaluation of Intradetrusor AbobotulinumtoxinA and IncobotulinumtoxinA in Women With Overactive Bladder AbobotulinumtoxinA 300 UNT, IncobotulinumtoxinA 100 UNT, Lidocain - Overactive Bladder | Phase 4 | Completed | Niko Kavcic | 64 | 2018-08-14 | 2024-02-12 |
| Lidocaine for Pain After Urodynamic Testing Lidocaine gel 2%, Standard lubricant gel - Voiding Disorders, Overactive Bladder | Phase 4 | Completed | Atlantic Health System | 134 | 2018-01-25 | 2019-07-19 |
| Efficacy and Safety of the Mirabegron Compared With Solifenacin in Treatment of Overactive Bladder Mirabegron 25mg, Solifenacin Succinate 5 MG - Overactive Bladder | Phase 4 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 81 | 2017-01-01 | 2018-06-19 |
| Investigation of the Effect of the Female Urinary Microbiome on Incontinence Estrogen Cream - Overactive Bladder, Incontinence | Phase 4 | Completed | Loyola University | 35 | 2016-09-01 | 2021-09-23 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Men With OAB Symptoms While Taking Tamsulosin Hydrochloride for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH) Mirabegron, Placebo, Tamsulosin Hydrochloride - Benign Prostatic Hyperplasia, Overactive Bladder | Phase 4 | Completed | Astellas Pharma Global Development, Inc. | 715 | 2016-06-13 | 2024-11-12 |
| A Phase 4 Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Male Subjects With Overactive Bladder (OAB) Symptoms, While Taking the Alpha Blocker for Benign Prostatic Hypertrophy (BPH) Mirabegron, Placebo, Tamsulosin - Overactive Bladder | Phase 4 | Completed | Astellas Pharma Inc | 568 | 2016-01-25 | 2024-11-12 |
| Mirabegron in Parkinson Disease and Impaired Cognition mirabegron, Placebo - Parkinson Disease, Overactive Bladder | Phase 4 | Completed | HealthPartners Institute | 7 | 2015-12-01 | 2019-05-08 |
| Reduction of Bladder Injection Pain With Belladonna Opiate Suppository Onabotulinumtoxin A (BoNT), belladonna, Morphine - Overactive Bladder, Urinary Urge Incontinence | Phase 4 | Completed | Edgar LeClaire, MD | 26 | 2015-11-01 | 2018-09-20 |
| A Safety and Efficacy Study of Botulinum Toxin Type A (BOTOX®) to Treat Urinary Incontinence Due to Neurogenic Detrusor Overactivity or Overactive Bladder in Korean Patients Botulinum Toxin Type A - Urinary Incontinence, Overactive Bladder | Phase 4 | Completed | Allergan | 168 | 2015-11-01 | 2016-07-21 |
| Fall Prevention in Older Adults With OAB Fesoterodine - Overactive Bladder | Phase 4 | Completed | University of Pennsylvania | 74 | 2015-07-25 | 2023-05-06 |
| Prospective Study for Patient Perception of Treatment Satisfaction After Switching to Mirabegron in Patients With Overactive Bladder Who Were Unsatisfied With Efficacy of Antimuscarinic Therapy or Adverse Event. mirabegron 50mg - Overactive Bladder | Phase 4 | Completed | Samsung Medical Center | 434 | 2015-06-01 | 2018-02-28 |
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Urinary Bladder, Overactive (56) · Urinary Incontinence, Urge (9) · Prostatic Hyperplasia (6) · Urinary Incontinence (5) · Lower Urinary Tract Symptoms (4) · Nocturia (2) · Cognition Disorders (1) · Cystitis, Interstitial (1) · Dementia (1) · Female Urogenital Diseases (1) · Mycoplasma Infections (1) · Obesity (1) · Pain (1) · Parkinson Disease (1) · Sleep Apnea, Obstructive (1)
Female Urogenital Diseases and Pregnancy Complications (56) · Male Urogenital Diseases (56) · Pathological Conditions, Signs and Symptoms (56) · Signs and Symptoms (56) · Urinary Bladder Diseases (56) · Urogenital Diseases (56) · Urologic Diseases (56) · Urological Manifestations (56) · Female Urogenital Diseases (55) · Lower Urinary Tract Symptoms (52) · Urination Disorders (13) · Urinary Incontinence (8) · Genital Diseases (6) · Genital Diseases, Male (6) · Prostatic Diseases (6)
Solifenacin Succinate (15) · mirabegron (9) · fesoterodine (6) · Botulinum Toxins, Type A (5) · Tamsulosin (5) · Tolterodine Tartrate (5) · trospium chloride (4) · oxybutynin (2) · AIEOP acute lymphoblastic leukemia protocol (1) · Adrenergic beta-3 Receptor Agonists (1) · Anti-Bacterial Agents (1) · Antibiotic Prophylaxis (1) · Azithromycin (1) · Cholinergic Antagonists (1) · Doxazosin (1)
Astellas Pharma Inc (7) · Allergan (6) · Samsung Medical Center (6) · Pfizer (3) · KYU-SUNG LEE (2) · Loyola University (2) · Uroplasty, Inc (2) · Asan Medical Center (1) · Astellas Pharma Global Development, Inc. (1) · Astellas Pharma Korea, Inc. (1) · Astellas Pharma Taiwan, Inc. (1) · Atlantic Health System (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Baylor Research Institute (1) · Boston Urogynecology Associates (1)
United States (27) · South Korea (15) · Canada (4) · Czechia (4) · France (4) · Italy (4) · Poland (4) · Germany (3) · Hungary (3) · Japan (3) · Russia (3) · Spain (3) · Taiwan (3) · Turkey (Türkiye) (3) · United Kingdom (3)
Kyu-Sung Lee, Ph.D (7) · Alan Wolfe, PhD (2) · Rose Khavari, MD (2) · Carly Crowder, MD (1) · Catherine Matthews, MD (1) · Edgar LeClaire, MD, FACOG (1) · Emily Slopnick, MD (1) · Felicia Lane, MD (1) · Hann-Chorng Kuo, M.D. (1) · Jeanette S. Brown, MD (1)
PMID 37160401, PMID 17132474, PMID 17187655, PMID 17983434, PMID 19912183, PMID 20690893, PMID 21175373, PMID 23973522, PMID 24415559, PMID 24552358, PMID 25363606, PMID 25401784, PMID 29324595, PMID 32665528, PMID 32791124, PMID 33208652, PMID 33245533, PMID 34807883, PMID 35412069, PMID 35881009, PMID 37811598, PMID 37991564, PMID 38484251, PMID 39101958, PMID 40025238
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