311 completed, 73 unknown, 46 terminated, 26 recruiting. 167 Not applicable, 85 Phase 4, 63 Phase 3, 58 Phase 2, 39 Phase 1.
Follow Overactive Bladder: new trials by email Literature Review of Overactive Bladder trials Research Report on Overactive Bladder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Defining the Safety and Efficacy of POSterIor Tibial NeRve StimulatiON in Children Urgent PC - Overactive Bladder, Overactive Bladder Syndrome | Phase 4 | Not yet recruiting | Chi Dang Hornik | 50 | 2027-04-01 | 2026-06-17 |
| Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease mirabegron, Exercise-based behavioral therapy - Overactive Bladder, Parkinson Disease | Phase 4 | Not yet recruiting | VA Office of Research and Development | 146 | 2026-11-09 | 2026-10-27 |
| Flyte Device for Improving Urinary Incontinence Among Endometrial and Cervical Cancer Survivors Who Have Undergone Radiation Therapy Educational Intervention, Interview, Flyte Medical Device Usage and Evaluation - Cervical Carcinoma, Endometrial Carcinoma | Not applicable | Recruiting | Mayo Clinic | 44 | 2026-08-20 | 2026-08-31 |
| Self-Start Triage Model for Post-Botox® Lower Urinary Tract Symptoms Macrobid® Capsules 100 mg, Standard Medical Care (SMC) - Overactive Bladder | Early Phase 1 | Recruiting | The Cleveland Clinic | 260 | 2026-07-31 | 2026-08-03 |
| SGLT-2 Inhibitors and Lower Urinary Tract Symptoms No Intervention: Observational Cohort - SGLT2 Inhibitors, Lower Urinary Track Symptoms | Active not recruiting | Marmara University | 40 | 2026-07-01 | 2026-07-21 | |
| Comparative Efficacy and Safety if Intravesical Botulinum Toxin A Versus Platelet-Rich Plasma in the Management of Refractory Overactive Bladder : A 2 Year Study Intravesical Botulinum Toxin A (100U), Intravesical Platelet-Rich Plasma - Overactive Bladder | Not applicable | Active not recruiting | Mahmoud Mohamed Farag Ali | 60 | 2026-06-01 | 2026-07-09 |
| Fluoroscopy Radiation Reduction During Sacral Neuromodulation Lead Placement Reduced radiation fluoroscopy, Conventional fluoroscopy - Radiation Exposure, Overactive Bladder | Not applicable | Recruiting | Loma Linda University | 44 | 2026-06-01 | 2026-03-06 |
| The Combined Effect of Intravesical Botox Injections and HoLEP Surgery in Treating Benign Prostatic Hyperplasia and Overactive Bladder Intravesical Botox injection - Benign Prostatic Hyperplasia, Overactive Bladder | Phase 4 | Withdrawn | University Hospitals Cleveland Medical Center | 2026-06-01 | 2025-09-05 | |
| The Role of Urinary RhoA, NGF, and BDNF Levels in Overactive Bladder and Vitamin D Deficiency Urotherapy - Overactive Bladder, Vitamin D Deficiency | Not applicable | Not yet recruiting | Tarik Emre Sener | 52 | 2026-05-01 | 2026-04-07 |
| Vitamin D Treat-to-Target Strategy for Children With Overactive Bladder-Wet urotherapy, Solifenacin Succinate, Vitamin D3 - Urinary Bladder, Overactive, Overactive Bladder | Not applicable | Recruiting | Children's Hospital of Chongqing Medical University | 180 | 2026-04-20 | 2026-04-17 |
| Add-On ZIDA Sock Therapy for Overactive Bladder ZIDA Control Sock - Overactive Bladder | Not applicable | Recruiting | Medical University of South Carolina | 20 | 2026-04-17 | 2026-05-06 |
| Turkish USIQ: Validity & Reliability Observational Cohort - Overactive Bladder | Not yet recruiting | Izmir Democracy University | 130 | 2026-04-15 | 2026-03-05 | |
| Mirabegron in Patients With Age-Related Macular Degeneration Mirabegron 50mg, Solifenacin 5mg - Dry AMD, Overactive Bladder | Not yet recruiting | University of Naples | 312 | 2026-04-01 | 2026-02-06 | |
| The Efficacy of Transcutaneous Tibial Nerve Stimulation in Women With Idiopathic Overactive Bladder Transcutaneous Tibial Nerve Stimulation, sham Transcutaneous Tibial Nerve Stimulation - Overactive Bladder | Not applicable | Enrolling by invitation | Inonu University | 30 | 2026-03-23 | 2026-03-24 |
| Bladder Overactivity and Post-Botulinum Toxin Telemonitoring home care - Overactive Bladder | Not applicable | Not yet recruiting | University Hospital, Grenoble | 112 | 2026-03-02 | 2026-01-30 |
| Efficacy of Gabapentin Combined With Solifenacin for Non-neurogenic Overactive Bladder in Women solifenacin combined with gabapentin, solifenacin monotherapy - Overactive Bladder | Phase 3 | Not yet recruiting | Mansoura University | 60 | 2026-02-01 | 2026-02-24 |
| A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask - Overactive Bladder, Neurogenic Bladder | Phase 4 | Not yet recruiting | TriHealth Inc. | 96 | 2026-02-01 | 2026-02-04 |
| Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly Chronic Kidney Disease, Overactive Bladder | Not yet recruiting | Chinese PLA General Hospital | 500 | 2026-01-01 | 2026-01-22 | |
| Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women Detrusor nerve radiofrequency ablation, Simulated (sham) detrusor nerve radiofrequency ablation - Overactive Bladder, Overactive Bladder (OAB) | Not applicable | Recruiting | InMode MD Ltd. | 202 | 2025-11-25 | 2026-01-30 |
| Predictive Utility and Mechanisms of Sacral Evoked Responses in Sacral Neuromodulation SNM based on visual-motor responses (VMRs), SNM based on sacral evoked responses (SERs) - Overactive Bladder | Not applicable | Recruiting | University of Michigan | 15 | 2025-10-16 | 2025-12-18 |
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Urinary Bladder, Overactive (498) · Urinary Incontinence, Urge (83) · Urinary Incontinence (75) · Lower Urinary Tract Symptoms (27) · Prostatic Hyperplasia (19) · Nocturia (12) · Multiple Sclerosis (10) · Urinary Incontinence, Stress (10) · Urinary Bladder, Neurogenic (9) · Urinary Tract Infections (8) · Urologic Diseases (8) · Cystitis, Interstitial (7) · Parkinson Disease (7) · Fecal Incontinence (6) · Hereditary Sensory and Autonomic Neuropathies (6)
Female Urogenital Diseases and Pregnancy Complications (498) · Pathological Conditions, Signs and Symptoms (498) · Signs and Symptoms (498) · Urogenital Diseases (498) · Urological Manifestations (498) · Female Urogenital Diseases (497) · Male Urogenital Diseases (497) · Urinary Bladder Diseases (495) · Urologic Diseases (490) · Lower Urinary Tract Symptoms (471) · Urination Disorders (148) · Urinary Incontinence (67) · Nervous System Diseases (37) · Genital Diseases (26) · Genital Diseases, Male (22)
Solifenacin Succinate (54) · Botulinum Toxins, Type A (42) · mirabegron (38) · Tolterodine Tartrate (34) · fesoterodine (24) · oxybutynin (13) · Tamsulosin (11) · Saline Solution (9) · Transcutaneous Electric Nerve Stimulation (9) · N-(4-((5-(hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-4-oxo-4,6,7,8-tetrahydropyrrolo(1,2-a)pyrimidine-6-carboxamide (8) · darifenacin (7) · trospium chloride (7) · propiverine (6) · imidafenacin (5) · Behavior Therapy (4)
Astellas Pharma Inc (21) · Allergan (17) · Pfizer (16) · Bayer (10) · Samsung Medical Center (8) · MedtronicNeuro (7) · The Cleveland Clinic (7) · Urovant Sciences GmbH (7) · GlaxoSmithKline (6) · Mayo Clinic (6) · Ankara Yildirim Beyazıt University (5) · Corewell Health East (5) · Loyola University (5) · Mansoura University (5) · Ono Pharmaceutical Co., Ltd. (5)
United States (218) · South Korea (45) · Canada (36) · Poland (30) · United Kingdom (29) · Belgium (28) · France (28) · Germany (26) · Turkey (Türkiye) (26) · Czechia (24) · Netherlands (23) · Spain (19) · Taiwan (19) · Denmark (17) · Russia (17)
Kyu-Sung Lee, Ph.D (8) · Rose Khavari, MD (4) · Seyda Toprak Celenay (4) · Hann-Chorng Kuo, M.D. (3) · Kenneth Peters, MD (3) · Stefan De Wachter, MD PhD FEBU (3) · Alan Wolfe, PhD (2)
PMID 37160401, PMID 37811598, PMID 35881009, PMID 17049716, PMID 32791124, PMID 36148895, PMID 12559262, PMID 23218404, PMID 24754838, PMID 25288099, PMID 25623739, PMID 26231052, PMID 26423260, PMID 32665528, PMID 35400537, PMID 10435146, PMID 10699609, PMID 10775736, PMID 11857671, PMID 11874310, PMID 12493342, PMID 12811491, PMID 14634406, PMID 15621220, PMID 15679789, PMID 15698871, PMID 15712851, PMID 15920223, PMID 16223407, PMID 16406907, PMID 16460875, PMID 17002859, PMID 17132474, PMID 17187655, PMID 17419703, PMID 17983434, PMID 18064739, PMID 18490916, PMID 18502028, PMID 18584946, PMID 19143854, PMID 19233423, PMID 19348029, PMID 19400928, PMID 19648387, PMID 19912183, PMID 19913821, PMID 19941278, PMID 20035977, PMID 20121659
2015 (4), 2014 (2), 2017 (2), 2018 (2), 2008 (1), 2019 (1), 2023 (1), I01RD000466 (1), R01AG047894 (1), R01AG075471 (1), R01DK103769 (1), R44DK121578 (1), U01HD041249 (1), U10HD041250 (1), U10HD041261 (1)