7 completed, 1 recruiting. 8 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 7, Recruiting 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow Ovarian Sarcoma: new trials by email Literature Review of Ovarian Sarcoma trials Research Report on Ovarian Sarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer GPC3 CD146 CAR-T cells - Ovarian Cancer, Ovarian Carcinoma | Phase 1 / Phase 2 | Recruiting | Essen Biotech | 80 | 2025-04-29 | 2025-07-16 |
| A Phase II Study of Akt Inhibitor MK2206 in the Treatment of Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer Akt Inhibitor MK2206, Laboratory Biomarker Analysis - Ovarian Sarcoma, Recurrent Fallopian Tube Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 6 | 2011-04-01 | 2016-06-24 |
| Psychosexual Intervention in Patients With Stage I-III Gynecologic or Breast Cancer behavioral, psychological or informational intervention - Ovarian Sarcoma, Ovarian Stromal Cancer | Phase 2 | Completed | Ohio State University Comprehensive Cancer Center | 100 | 2010-10-01 | 2018-05-30 |
| Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Gamma-Secretase Inhibitor RO4929097, Laboratory Biomarker Analysis, Pharmacological Study - Adult Alveolar Soft Part Sarcoma, Adult Angiosarcoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 78 | 2010-06-01 | 2018-08-15 |
| Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery therapeutic angiotensin-(1-7), laboratory biomarker analysis - Bone Cancer, Chondrosarcoma | Phase 2 | Completed | Wake Forest University Health Sciences | 20 | 2009-10-01 | 2018-07-05 |
| Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies stereotactic radiosurgery, quality-of-life assessment - Fallopian Tube Cancer, Ovarian Sarcoma | Phase 2 | Completed | Case Comprehensive Cancer Center | 50 | 2009-05-01 | 2013-11-28 |
| Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma ziv-aflibercept - Fallopian Tube Cancer, Female Reproductive Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 63 | 2006-09-01 | 2015-12-07 |
| Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma sorafenib tosylate - Adult Angiosarcoma, Adult Epithelioid Sarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 147 | 2005-09-01 | 2014-05-23 |
Fallopian Tube Neoplasms (4) · Carcinoma, Ovarian Epithelial (3) · Sarcoma (3) · Chondrosarcoma (2) · Endometrial Neoplasms (2) · Hemangiosarcoma (2) · Histiocytoma, Malignant Fibrous (2) · Leiomyosarcoma (2) · Neurofibrosarcoma (2) · Osteosarcoma (2) · Ovarian Neoplasms (2) · Sarcoma, Synovial (2) · Uterine Cervical Neoplasms (2) · Vaginal Neoplasms (2) · Vulvar Neoplasms (2)
Neoplasms (7) · Neoplasms by Histologic Type (6) · Neoplasms by Site (6) · Adnexal Diseases (5) · Endocrine Gland Neoplasms (5) · Endocrine System Diseases (5) · Female Urogenital Diseases (5) · Female Urogenital Diseases and Pregnancy Complications (5) · Genital Diseases (5) · Genital Diseases, Female (5) · Genital Neoplasms, Female (5) · Gonadal Disorders (5) · Ovarian Diseases (5) · Urogenital Diseases (5) · Urogenital Neoplasms (5)
2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide (1) · HhAntag691 (1) · MK 2206 (1) · Radiosurgery (1) · Sorafenib (1) · aflibercept (1) · angiotensin I (1-7) (1)
National Cancer Institute (NCI) (4) · Case Comprehensive Cancer Center (1) · Essen Biotech (1) · Ohio State University Comprehensive Cancer Center (1) · Wake Forest University Health Sciences (1)
United States (7) · Canada (1) · China (1)
Amit Oza (1) · Joyce Liu (1) · Kristen M. Carpenter, Ph.D (1) · Mrinal Gounder (1) · Robert DeBernardo, MD (1) · Robert Maki (1) · William Petty (1)
N01CM62201 (2), N01CM62206 (2), P30CA008748 (2), N01CM62203 (1), N01CM62209 (1), P30CA006516 (1), R21CA149675 (1), U01CA069856 (1)