15 completed, 2 recruiting, 1 terminated. 8 Phase 2, 7 Phase 1, 3 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 7, Recruiting 1 |
| Phase 1 | 7 | Completed 6, Recruiting 1 |
| Not applicable | 3 | Completed 2, Terminated 1 |
Follow Ovarian Sarcoma: new trials by email Literature Review of Ovarian Sarcoma trials Research Report on Ovarian Sarcoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer GPC3 CD146 CAR-T cells - Ovarian Cancer, Ovarian Carcinoma | Phase 1 / Phase 2 | Recruiting | Essen Biotech | 80 | 2025-04-29 | 2025-07-16 |
| International PPB/DICER1 Registry Pleuropulmonary Blastoma, Sertoli-Leydig Cell Tumor | Recruiting | Children's Hospitals and Clinics of Minnesota | 3400 | 2016-12-06 | 2026-10-26 | |
| Carboplatin, Gemcitabine Hydrochloride, and Stereotactic Body Radiation Therapy in Gynecological Cancer stereotactic body radiation therapy, carboplatin, gemcitabine hydrochloride - Leydig Cell Tumor, Ovarian Sarcoma | Phase 1 | Completed | Case Comprehensive Cancer Center | 12 | 2012-05-01 | 2015-08-04 |
| A Phase II Study of Akt Inhibitor MK2206 in the Treatment of Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer Akt Inhibitor MK2206, Laboratory Biomarker Analysis - Ovarian Sarcoma, Recurrent Fallopian Tube Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 6 | 2011-04-01 | 2016-06-24 |
| Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer questionnaire administration, quality-of-life assessment, psychosocial assessment and care - Anxiety Disorder, Depression | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 39 | 2010-10-01 | 2015-10-09 |
| Psychosexual Intervention in Patients With Stage I-III Gynecologic or Breast Cancer behavioral, psychological or informational intervention - Ovarian Sarcoma, Ovarian Stromal Cancer | Phase 2 | Completed | Ohio State University Comprehensive Cancer Center | 100 | 2010-10-01 | 2018-05-30 |
| Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Gamma-Secretase Inhibitor RO4929097, Laboratory Biomarker Analysis, Pharmacological Study - Adult Alveolar Soft Part Sarcoma, Adult Angiosarcoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 78 | 2010-06-01 | 2018-08-15 |
| Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) HIPEC Orientation, Consultation with Survivorship Navigator, Questionnaires - Advanced Malignant Mesothelioma, Carcinoma of the Appendix | Not applicable | Completed | Wake Forest University Health Sciences | 10 | 2010-05-01 | 2018-07-03 |
| Changes in Brain Function in Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Are Receiving Chemotherapy Cognitive Assessment, Quality-of-Life Assessment - Cognitive Side Effects of Cancer Therapy, Malignant Ovarian Epithelial Tumor | Completed | Gynecologic Oncology Group | 247 | 2010-04-01 | 2018-04-12 | |
| Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery therapeutic angiotensin-(1-7), laboratory biomarker analysis - Bone Cancer, Chondrosarcoma | Phase 2 | Completed | Wake Forest University Health Sciences | 20 | 2009-10-01 | 2018-07-05 |
| Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies stereotactic radiosurgery, quality-of-life assessment - Fallopian Tube Cancer, Ovarian Sarcoma | Phase 2 | Completed | Case Comprehensive Cancer Center | 50 | 2009-05-01 | 2013-11-28 |
| Temsirolimus, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Tumors paclitaxel, carboplatin, temsirolimus - Ovarian Sarcoma, Ovarian Stromal Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 38 | 2007-02-01 | 2014-06-19 |
| Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma ziv-aflibercept - Fallopian Tube Cancer, Female Reproductive Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 63 | 2006-09-01 | 2015-12-07 |
| Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma sorafenib tosylate - Adult Angiosarcoma, Adult Epithelioid Sarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 147 | 2005-09-01 | 2014-05-23 |
| EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer EF5, motexafin lutetium, pharmacological study - Advanced Adult Primary Liver Cancer, Carcinoma of the Appendix | Not applicable | Terminated | National Cancer Institute (NCI) | 30 | 2004-05-01 | 2013-01-16 |
| 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) 7-hydroxystaurosporine, irinotecan hydrochloride, diagnostic laboratory biomarker analysis - Advanced Adult Primary Liver Cancer, Carcinoma of the Appendix | Phase 1 | Completed | National Cancer Institute (NCI) | 41 | 2001-12-01 | 2013-09-30 |
| Vaccine Therapy in Treating Patients With Metastatic Cancer interleukin-2, MAGE-12 peptide vaccine, Montanide ISA-51 - Lung Cancer, Adult Soft Tissue Sarcoma | Phase 1 | Completed | National Cancer Institute (NCI) | 2000-07-01 | 2024-03-04 | |
| 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma tanespimycin, pharmacological study - AIDS-related Peripheral/Systemic Lymphoma, AIDS-related Primary CNS Lymphoma | Phase 1 | Completed | National Cancer Institute (NCI) | 60 | 1999-10-01 | 2013-02-07 |
Carcinoma, Ovarian Epithelial (9) · Fallopian Tube Neoplasms (8) · Endometrial Neoplasms (6) · Sarcoma (6) · Uterine Cervical Neoplasms (5) · Breast Neoplasms (4) · Colonic Neoplasms (4) · Osteosarcoma (4) · Vaginal Neoplasms (4) · Vulvar Neoplasms (4) · Appendiceal Neoplasms (3) · Carcinoma, Non-Small-Cell Lung (3) · Chondrosarcoma (3) · Gastrointestinal Stromal Tumors (3) · Histiocytoma, Malignant Fibrous (3)
Neoplasms (16) · Neoplasms by Histologic Type (16) · Neoplasms by Site (16) · Neoplasms, Glandular and Epithelial (14) · Adnexal Diseases (13) · Endocrine Gland Neoplasms (13) · Endocrine System Diseases (13) · Female Urogenital Diseases (13) · Female Urogenital Diseases and Pregnancy Complications (13) · Genital Diseases (13) · Genital Diseases, Female (13) · Genital Neoplasms, Female (13) · Gonadal Disorders (13) · Ovarian Diseases (13) · Urogenital Diseases (13)
Carboplatin (2) · Radiosurgery (2) · 2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide (1) · 7-hydroxystaurosporine (1) · Behavior Therapy (1) · Early Intervention, Educational (1) · Gemcitabine (1) · HhAntag691 (1) · Interleukin-2 (1) · Irinotecan (1) · MK 2206 (1) · Mental Status and Dementia Tests (1) · Methods (1) · Paclitaxel (1) · Pharmacogenomic Testing (1)
National Cancer Institute (NCI) (9) · Case Comprehensive Cancer Center (2) · Ohio State University Comprehensive Cancer Center (2) · Wake Forest University Health Sciences (2) · Children's Hospitals and Clinics of Minnesota (1) · Essen Biotech (1) · Gynecologic Oncology Group (1)
United States (16) · Canada (2) · China (1)
Amit Oza (2) · Barbara Andersen, PhD (1) · Francesco M. Marincola (1) · Joyce Liu (1) · Kris Ann P Schultz, MD (1) · Kristen M. Carpenter, Ph.D (1) · Lisa Hess (1) · Mrinal Gounder (1) · Paula Fracasso (1) · Ramesh Ramanathan (1) · Richard McQuellon (1) · Robert DeBernardo, MD (1) · Robert Maki (1) · Stephen Michael Hahn (1) · Steven Waggoner, MD (1)
PMID 19556464, PMID 25209242, PMID 27441995, PMID 28674120, PMID 29343557, PMID 30178239, PMID 30339877, PMID 30672147, PMID 30677214, PMID 30715996, PMID 30824630, PMID 31296931, PMID 31820118, PMID 31838154, PMID 31952842, PMID 32291395, PMID 32415267, PMID 33119505, PMID 33484847, PMID 33570641, PMID 33630087, PMID 33637876, PMID 33782093, PMID 33875804, PMID 40082377
N01CM62201 (2), N01CM62206 (2), P30CA008748 (2), N01CM62203 (1), N01CM62209 (1), P01CA087971 (1), P30CA006516 (1), P30CA044579 (1), R21CA135005 (1), R21CA149675 (1), U01CA069856 (1), U01CA099168 (1), U10CA101165 (1)