2 completed, 2 terminated, 1 recruiting, 1 unknown. 7 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 2, Terminated 2, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
Follow Oropharynx Cancer: new trials by email Literature Review of Oropharynx Cancer trials Research Report on Oropharynx Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers E7 TCR-T cells, Aldesleukin - HPV-Associated Cervical Carcinoma, HPV-Related Carcinoma | Phase 1 / Phase 2 | Recruiting | Christian Hinrichs | 15 | 2025-08-11 | 2026-10-28 |
| A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers Zimberelimab, Etrumadenant, Cisplatin - Head and Neck Cancer, Squamous Cell Carcinoma of Head and Neck | Phase 1 | Withdrawn | Jennifer Choe | 2023-12-31 | 2023-11-30 | |
| Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors TBio-6517, Pembrolizumab - Solid Tumor, Microsatellite Stable Colorectal Cancer | Phase 1 | Terminated | Turnstone Biologics, Corp. | 27 | 2020-06-02 | 2025-04-23 |
| Allogeneic Mesenchymal Stem Cells for Radiation-induced Hyposalivation and Xerostomia/Dry Mouth Allogeneic adipose derived stem/stromal cells - Xerostomia Due to Radiotherapy, Hyposalivation | Phase 1 | Unknown | Copenhagen University Hospital, Rigshospitalet | 10 | 2019-03-18 | 2021-01-29 |
| Pembrolizumab in Combination With CRT for LA-SCCHN pembrolizumab (MK-3475), Cisplatin, Radiation - Head and Neck Cancer, Squamous Cell Carcinoma | Phase 1 | Completed | Sanford Health | 59 | 2015-11-01 | 2025-10-07 |
| TPF-Induction Chemotherapy of Oropharyngeal and Cavity of the Mouth Cancer Taxotere, Cisplatin, 5-Fluorouracil (5-FU) - Oropharynx Cancer, Squamous Cell Carcinoma of the Oral Cavity | Phase 1 / Phase 2 | Completed | Orlando Guntinas-Lichius, Prof. Dr. med. | 71 | 2009-11-01 | 2016-05-18 |
| Motexafin Gadolinium With Chemotherapy and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer Motexafin Gadolinium Injection - Head and Neck Cancer, Oropharynx Cancer | Phase 1 | Terminated | Pharmacyclics LLC. | 18 | 2007-05-08 |
Oropharyngeal Neoplasms (7) · Head and Neck Neoplasms (3) · Hypopharyngeal Neoplasms (3) · Laryngeal Neoplasms (3) · Mouth Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (2) · Uterine Cervical Neoplasms (2) · Anus Neoplasms (1) · Carcinoma, Renal Cell (1) · Carcinoma, Squamous Cell (1) · Laryngeal Diseases (1) · Melanoma (1) · Mesothelioma (1) · Penile Neoplasms (1) · Pharyngeal Neoplasms (1)
Neoplasms (7) · Neoplasms by Site (7) · Otorhinolaryngologic Diseases (7) · Otorhinolaryngologic Neoplasms (7) · Pharyngeal Diseases (7) · Stomatognathic Diseases (7) · Pharyngeal Neoplasms (6) · Carcinoma (4) · Head and Neck Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms, Glandular and Epithelial (4) · Mouth Diseases (3) · Respiratory Tract Diseases (3) · Respiratory Tract Neoplasms (3) · Carcinoma, Squamous Cell (2)
Cisplatin (3) · Radiation (2) · pembrolizumab (2) · Adoptive Transfer (1) · Docetaxel (1) · Fluorouracil (1) · aldesleukin (1) · motexafin gadolinium (1) · zimberelimab (1)
Christian Hinrichs (1) · Copenhagen University Hospital, Rigshospitalet (1) · Jennifer Choe (1) · Orlando Guntinas-Lichius, Prof. Dr. med. (1) · Pharmacyclics LLC. (1) · Sanford Health (1) · Turnstone Biologics, Corp. (1)
United States (4) · Canada (1) · Denmark (1) · Germany (1) · South Korea (1)
Charlotte Lynggaard, MD (1) · Christian S Hinrichs, MD (1) · Ines Verdon, MD (1) · Jennifer Choe, MD, PhD (1) · Orlando Guntinas-Lichius, Prof. Dr. (1) · Steven F Powell, MD (1)
PMID 23083061, PMID 26186556, PMID 28498880, PMID 32479189
2009 (1), 2018 (1)