7 completed, 2 unknown. 9 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 7, Unknown 2 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
Follow Opiate Dependence: new trials by email Literature Review of Opiate Dependence trials Research Report on Opiate Dependence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Remote Observed Dosing of Suboxone to Improve Clinical Practice Suboxone Remote Observed Dosing, Suboxone Attention Control - Opioid-use Disorder, Opioid Dependence | Phase 1 / Phase 2 | Completed | University of Pennsylvania | 16 | 2019-04-01 | 2023-07-27 |
| Study to Evaluate the Exposures of Lofexidine and Its Major Metabolites in Subjects Seeking Buprenorphine Dose Reduction lofexidine administration in subjects seeking buprenorphine dose reduction - Substance Withdrawal Syndrome, Opiate Addiction | Phase 1 | Completed | USWM, LLC (dba US WorldMeds) | 10 | 2016-06-01 | 2017-10-26 |
| Study of Buprenorphine-Naloxone Sublingual Spray and Suboxone® Sublingual Film in Healthy Volunteers SL spray, SL film - Opiate Dependence | Phase 1 | Completed | INSYS Therapeutics Inc | 47 | 2015-06-01 | 2015-09-03 |
| Oxytocin in Opiate Dependence: A Pilot Study of the Effects of Intranasal Oxytocin on Emotional Processes and Stress Responses in Patients With Opiate Dependence Oxytocin - Opiate Dependence | Phase 1 | Unknown | MacDonald, Kai, M.D. | 2013-01-01 | 2014-09-15 | |
| Developing a Smoking Cessation Intervention for Methadone Maintained Smokers Intensive, tailored intervention, NJ Quitline Referral - Nicotine Dependence, Opiate Dependence | Phase 1 | Completed | Rutgers, The State University of New Jersey | 87 | 2011-10-01 | 2018-09-06 |
| Cognitive-Behavioral Therapy for Pain and Opioid Dependence in Methadone Maintenance Treatment Cognitive-Behavioral Therapy for Pain and Opioid Dependence, Methadone Drug Counseling - Chronic Pain, Opiate Dependence | Phase 1 | Completed | Yale University | 40 | 2011-04-01 | 2020-04-03 |
| Clinical Trial of Integrated Treatment for Pain and Opioid Dependence CBT, Buprenorphine, Educational Counseling - Opiate Dependence, Chronic Pain | Phase 1 / Phase 2 | Completed | Yale University | 90 | 2009-09-01 | 2021-08-02 |
| Community Reinforcement and Family Training for Drug Abuse Treatment Retention/HIV Risk Reduction CRAFT-T, Treatment as usual - Heroin Dependence, Opiate Dependence | Phase 1 / Phase 2 | Unknown | University of Cincinnati | 104 | 2008-03-01 | 2012-08-14 |
| Acceptance Therapy During Methadone Detoxification Behavior Therapy, Drug Counseling - Opiate Dependence | Phase 1 | Completed | The University of Texas Health Science Center, Houston | 56 | 2006-07-01 | 2013-05-06 |
Opioid-Related Disorders (9) · Chronic Pain (2) · Substance-Related Disorders (2) · Heroin Dependence (1) · Smoking Cessation (1) · Substance Withdrawal Syndrome (1) · Tobacco Use Disorder (1)
Chemically-Induced Disorders (9) · Mental Disorders (9) · Narcotic-Related Disorders (9) · Substance-Related Disorders (7) · Neurologic Manifestations (2) · Pain (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Behavior (1) · Health Behavior (1)
Buprenorphine (2) · Behavior Therapy (1) · Cognitive Behavioral Therapy (1) · Oxytocin (1) · Practice Management (1) · Therapeutics (1)
Yale University (2) · INSYS Therapeutics Inc (1) · MacDonald, Kai, M.D. (1) · Rutgers, The State University of New Jersey (1) · The University of Texas Health Science Center, Houston (1) · USWM, LLC (dba US WorldMeds) (1) · University of Cincinnati (1) · University of Pennsylvania (1)
United States (9)
Angela L Stotts, Ph.D. (1) · Brenda Curtis, PhD (1) · Declan Barry, PhD (1) · Giovanni DeCastro (1) · Gregory S. Brigham, Ph.D. (1) · Kyle Kampman, MD (1) · Nina Cooperman, Psy.D. (1) · Richard S Schottenfeld, MD (1)
K23DA021512 (1), K23DA024050 (1), K23DA025049 (1), R01DA019436 (1), R01DA024695 (1), U34DA045177 (1)