8 recruiting. 8 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Recruiting 8 |
| Phase 2 | 7 | Recruiting 7 |
Follow Obstructive Sleep Apnea: new trials by email Literature Review of Obstructive Sleep Apnea trials Research Report on Obstructive Sleep Apnea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep Apnea Combination device and drug: Unilateral hypoglossal nerve stimulation & atomoxetine-plus-oxybutynin (HGNS+AtoOxy), Unilateral hypoglossal nerve stimulation (HGNS), active comparator condition, Atomoxetine-plus-oxybutynin (80/5 mg) (AtoOxy), active comparator condition - Obstructive Sleep Apnea, Sleep-disordered Breathing | Phase 1 / Phase 2 | Recruiting | Brigham and Women's Hospital | 24 | 2026-09-01 | 2026-09-21 |
| DRonabinol Treatment of OSA Dronabinol - Obstructive Sleep Apnea | Phase 1 / Phase 2 | Recruiting | VA Office of Research and Development | 120 | 2025-08-25 | 2026-08-11 |
| Exploring the Use of Phototherapy to Improve CPAP Compliance Phototherapy - Obstructive Sleep Apnea | Phase 1 | Recruiting | University of Alberta | 30 | 2024-01-05 | 2026-05-08 |
| Trazodone on OSA Endotypes Placebo oral tablet, Trazodone Hydrochloride - Obstructive Sleep Apnea | Phase 1 / Phase 2 | Recruiting | Brigham and Women's Hospital | 18 | 2024-01-01 | 2025-02-06 |
| Rescue Pharmacotherapy for OSA Placebo, Acetazolamide, Trazodone - Obstructive Sleep Apnea | Phase 1 / Phase 2 | Recruiting | Brigham and Women's Hospital | 70 | 2023-07-01 | 2026-07-15 |
| Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities Mild Intermittent Hypoxia, Sham MIH - Obstructive Sleep Apnea | Phase 1 / Phase 2 | Recruiting | VA Office of Research and Development | 60 | 2023-01-01 | 2025-12-04 |
| Atomoxetine and DAW2022 on OSA Severity Placebo oral capsule, Atomoxetine Oral Capsule [Strattera] - Obstructive Sleep Apnea | Phase 1 / Phase 2 | Recruiting | Brigham and Women's Hospital | 18 | 2022-06-01 | 2026-07-10 |
| Pharmacological Activation of HMN for OSA Aim 2 Placebo oral capsule, LTM1201AZ, LTM1201AT - Obstructive Sleep Apnea | Phase 1 / Phase 2 | Recruiting | Brigham and Women's Hospital | 16 | 2019-03-01 | 2022-09-21 |
Sleep Apnea, Obstructive (8) · Sleep Apnea Syndromes (2)
Apnea (8) · Dyssomnias (8) · Nervous System Diseases (8) · Respiration Disorders (8) · Respiratory Tract Diseases (8) · Sleep Disorders, Intrinsic (8) · Sleep Wake Disorders (8) · Sleep Apnea Syndromes (6)
Atomoxetine Hydrochloride (2) · Trazodone (2) · Acetazolamide (1) · Dronabinol (1) · Eszopiclone (1) · Phototherapy (1)
Brigham and Women's Hospital (5) · VA Office of Research and Development (2) · University of Alberta (1)
United States (7) · Canada (1)
Bharati Prasad, MD (1) · Jason H Mateika, PhD MS BS (1) · Scott A Sands, PhD (1)