4 completed, 3 unknown, 2 recruiting, 1 withdrawn. 4 Phase 2, 3 Phase 1, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Recruiting 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 2, Recruiting 1 |
| Not applicable | 2 | Recruiting 1, Unknown 1 |
Follow Noise Induced Hearing Loss: new trials by email Literature Review of Noise Induced Hearing Loss trials Research Report on Noise Induced Hearing Loss
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2b Study of SPI-1005 to Prevent Acute Noise Induced Hearing Loss SPI-1005 200mg, SPI-1005 400mg, Placebo - Noise Induced Hearing Loss | Phase 2 | Withdrawn | Sound Pharmaceuticals, Incorporated | 2026-06-01 | 2026-06-03 | |
| Prevention of Noise-Induced Hearing Loss in Primary Education HoorToren educational package - Effectiveness of Application Education Intervention, Noise Induced Hearing Loss | Not applicable | Recruiting | Erasmus Medical Center | 600 | 2026-03-30 | 2026-04-06 |
| A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise, Placebo Drug With Engineered Sound - Central Auditory Processing Disorder, Hearing Impaired (Partially) | Phase 1 / Phase 2 | Recruiting | University of Colorado, Denver | 344 | 2025-03-31 | 2026-04-30 |
| Determination of the Effects of Noise Level in the Operating Room No intervention - Noise; Adverse Effect, Noise Induced Hearing Loss | Unknown | Baskent University | 500 | 2022-12-01 | 2022-12-05 | |
| The Effect of Acupuncture on Patients With Noise-induced Hearing Loss electroacupuncture - Electroacupuncture, Noise Induced Hearing Loss | Not applicable | Unknown | China Medical University Hospital | 80 | 2022-09-01 | 2022-08-23 |
| FX-322 in Adults With Acquired Sensorineural Hearing Loss FX-322, Placebo - Hearing Loss, Sensorineural, Noise Induced Hearing Loss | Phase 2 | Completed | Frequency Therapeutics | 142 | 2021-10-12 | 2023-04-21 |
| FX-322 in Adults With Severe Sensorineural Hearing Loss FX-322, Placebo - Hearing Loss, Sensorineural, Noise Induced Hearing Loss | Phase 1 | Completed | Frequency Therapeutics | 31 | 2020-11-02 | 2022-02-01 |
| FX-322 in Adults With Age-Related Sensorineural Hearing Loss FX-322, placebo - Presbycusis, Hearing Loss, Sensorineural | Phase 1 | Completed | Frequency Therapeutics | 30 | 2020-09-17 | 2022-05-25 |
| ABR Characteristics and Salivary Cortisone Concentration in Noise-exposed Workers ABR and salivary cortisone testing - Sensorineural Hearing Loss, Noise Induced Hearing Loss | Unknown | University Hospital Sestre Milosrdnice | 100 | 2019-11-01 | 2019-12-05 | |
| FX-322 in Adults With Stable Sensorineural Hearing Loss FX-322 (One Dose), FX-322 (Two Doses), FX-322 (Four Doses) - Sensorineural Hearing Loss, Noise Induced Hearing Loss | Phase 2 | Completed | Frequency Therapeutics | 95 | 2019-10-04 | 2023-04-27 |
Hearing Loss, Noise-Induced (10) · Hearing Loss, Sensorineural (6) · Hearing Loss, Sudden (4) · Presbycusis (2) · Auditory Diseases, Central (1) · Hearing Disorders (1) · Hearing Loss (1) · Hearing Loss, Hidden (1) · Language Development Disorders (1) · Vestibulocochlear Nerve Diseases (1)
Ear Diseases (10) · Nervous System Diseases (10) · Neurologic Manifestations (10) · Otorhinolaryngologic Diseases (10) · Pathological Conditions, Signs and Symptoms (10) · Sensation Disorders (10) · Signs and Symptoms (10) · Hearing Disorders (9) · Hearing Loss (9) · Hearing Loss, Sensorineural (4) · Retrocochlear Diseases (2) · Brain Diseases (1) · Central Nervous System Diseases (1) · Communication Disorders (1) · Cranial Nerve Diseases (1)
Clemastine (1) · Contraceptives, Oral (1) · Electroacupuncture (1) · Placebo Effect (1) · ebselen (1)
Frequency Therapeutics (4) · Baskent University (1) · China Medical University Hospital (1) · Erasmus Medical Center (1) · Sound Pharmaceuticals, Incorporated (1) · University Hospital Sestre Milosrdnice (1) · University of Colorado, Denver (1)
United States (6) · Croatia (1) · Netherlands (1)
Carl LeBel, PhD (4) · Achim Klug, PhD (1) · Jonathan Kil, MD (1) · Mihael Ries, MD, PhD (1) · Samuel A Budoff, PhD, MS (1)