12 completed, 9 recruiting, 4 unknown, 3 not yet recruiting. 28 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 28 | Completed 12, Recruiting 9, Unknown 4, Not yet recruiting 3 |
Follow Nephrosis: new trials by email Literature Review of Nephrosis trials Research Report on Nephrosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single-cell RNA Sequencing (scRNA-seq) to Investigate the Mechanisms Underlying the Induction of Regulatory T Cells in Patients With Extramembranous Glomerulonephritis Treated With Rituximab Peripheral blood immune-cell profiling by single-cell RNA sequencing and in vitro pathway modulation assays - Membranous Nephropathy, Membranous Nephropathy - PLA2R Induced | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Nice | 12 | 2026-10-31 | 2026-09-10 |
| Comparison of Efficacy and Safety of Albumin Versus Fresh Frozen Plasma in Managing Diuretic Resistant Edema in Children With Idiopathic Nephrotic Syndrome. Human Albumin 20%, Fresh Frozen Plasma - Idiopathic Nephrotic Syndrome (INS) | Not applicable | Not yet recruiting | Qamar Shafiq | 56 | 2026-07-05 | 2026-07-06 |
| A Smart Phone Application to Improve Adoption of the 2024 Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease (CKD) Guidelines Use of an electronic digital Application - Chronic Kidney Disease, Proteinuria | Not applicable | Recruiting | St. James's Hospital, Ireland | 80 | 2026-01-14 | 2026-05-01 |
| Edoxaban Steady-State PK/PD in Adults With Nephrotic Syndrome Edoxaban 60 mg, Enoxaparin 40 mg - Nephrotic Syndrome, Hypoalbuminemia | Not applicable | Not yet recruiting | Peking University People's Hospital | 60 | 2025-09-01 | 2025-08-11 |
| Multitarget Strategy for Primary Podocytopathies Biologic fluid sampling - Nephrotic Syndrome | Not applicable | Recruiting | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 150 | 2025-06-19 | 2026-03-27 |
| SLIT ABS: Study on Patients With Autoimmune Podocytopathy Serum and renal tissue analysis - Nephrotic Syndrome With Edema (Diagnosis), Minimal Change Nephrotic Syndrome | Not applicable | Recruiting | Meyer Children's Hospital IRCCS | 50 | 2025-06-10 | 2026-04-08 |
| The Role of Vitamin K2 in Preventing Glucocorticoid-Induced Bone Loss in Children With Nephrotic Syndrome Vitamin K 2 - Pediatrics Nephrology | Not applicable | Recruiting | Ain Shams University | 60 | 2025-04-01 | 2025-10-03 |
| Cardiac Performance Evaluation in Children With Steroid Dependent vs Steroid Resistant Nephrotic Syndrome Tissue Doppler imaging and Conventional Echocardiography - Nephrotic Syndrome | Not applicable | Recruiting | Sohag University | 60 | 2024-07-15 | 2024-10-02 |
| Effectiveness of Educational Gamified Cards About Nephrotic Syndrome Gamified Cards about Nephrotic Syndrome - Nephrotic Syndrome | Not applicable | Completed | Mansoura University | 40 | 2024-06-01 | 2025-04-22 |
| Efficacy of Zinc Supplementation in Maintaining Sustained Remission in Children With Steroid-sensitive Nephrotic Syndrome Zinc supplementation plus standard treatment - Steroid-Sensitive Nephrotic Syndrome | Not applicable | Completed | Muhammad Aamir Latif | 192 | 2024-01-01 | 2025-03-06 |
| Diuretic Tuner Clinical Decision Support Diuretic Tuner - Edema, Hypervolemia | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 30 | 2023-11-20 | 2026-10-29 |
| The Effect of Self-Efficacy Promoting Program Using Computer Game on Proteinuria in Thai Children With Nephrotic Syndrome Self-efficacy promoting program using computer game, Standard nursing care - Nephrotic Syndrome in Children | Not applicable | Completed | Chulalongkorn University | 40 | 2023-03-01 | 2024-07-29 |
| taVNS for FRNS in Children Transcutaneous auricular vagus nerve stimulation, Sham device - Nephrotic Syndrome in Children, Minimal Change Disease | Not applicable | Recruiting | Northwell Health | 30 | 2023-01-05 | 2026-04-15 |
| A Pilot Trial of taVNS for SRNS in Children (kidNEY-VNS) trascutaneous auricular vagus nerve stimulation, Sham device - Nephrotic Syndrome in Children, Minimal Change Disease | Not applicable | Recruiting | Northwell Health | 10 | 2022-09-19 | 2026-04-17 |
| NEPTUNE Match Study Communication - Nephrotic Syndrome in Children, Focal Segmental Glomerulosclerosis | Not applicable | Recruiting | University of Michigan | 375 | 2022-05-02 | 2026-11-10 |
| Implementation of a Diagnostic Workflow for Personalized Diagnosis of Nephrotic Syndrome Anti-nephrin antibodies, u-RPC cultures - Nephrotic Syndrome | Not applicable | Unknown | Meyer Children's Hospital IRCCS | 150 | 2022-01-26 | 2024-03-22 |
| Rituximab and Targeted Nursing for Pediatric Nephrotic Syndrome Rituximab, Targeted Nursing Care, Baseline Glucocorticoid Therapy - Nephrotic Syndrome in Children | Not applicable | Completed | Wuhan Children's Hospital | 91 | 2021-01-01 | 2025-10-01 |
| Comparison of Relapse Rate After 12 Weeks Verses 20 Weeks Steroid Therapy for the Management of First Episode of Steroid Sensitive Nephrotic Syndrome Prednisolone - Steroid-Sensitive Nephrotic Syndrome | Not applicable | Unknown | Shaheed Zulfiqar Ali Bhutto Medical University | 68 | 2020-12-22 | 2021-05-11 |
| Effect of Daily Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Proteinuria in Pediatric Patients With Idiopathic Nephrotic Syndrome Transcutaneous Auricular Vagus Nerve (taVNS) stimulation - Idiopathic Nephrotic Syndrome, Frequently Relapsing Nephrotic Syndrome | Not applicable | Completed | Northwell Health | 7 | 2019-12-01 | 2022-09-28 |
| UrApp for Childhood Nephrotic Syndrome Management (Incident Cohort) Standard of Care, UrApp - Idiopathic Nephrotic Syndrome | Not applicable | Completed | Emory University | 58 | 2019-09-17 | 2025-11-06 |
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Nephrotic Syndrome (22) · Nephrosis, Lipoid (9) · Glomerulosclerosis, Focal Segmental (6) · Glomerulonephritis, Membranous (5) · Proteinuria (4) · Kidney Diseases (2) · Renal Insufficiency, Chronic (2) · Disease (1) · Edema (1) · Glomerulonephritis (1) · Glomerulonephritis, IGA (1) · Hypoalbuminemia (1) · Macular dystrophy, corneal type 1 (1) · Nephritis, Hereditary (1) · Recurrence (1)
Female Urogenital Diseases (28) · Female Urogenital Diseases and Pregnancy Complications (28) · Male Urogenital Diseases (28) · Urogenital Diseases (28) · Urologic Diseases (28) · Kidney Diseases (26) · Nephritis (9) · Glomerulonephritis (8) · Pathological Conditions, Signs and Symptoms (7) · Autoimmune Diseases (5) · Immune System Diseases (5) · Signs and Symptoms (5) · Pathologic Processes (4) · Urination Disorders (4)
Rituximab (2) · Adrenal Cortex Hormones (1) · Amoxicillin (1) · Blood Specimen Collection (1) · Cholecalciferol (1) · Clarithromycin (1) · Cyclophosphamide (1) · Enoxaparin (1) · Furosemide (1) · Galactose (1) · Lansoprazole (1) · Prednisolone (1) · Prednisone (1) · Saline Solution, Hypertonic (1) · Sodium Chloride (1)
Northwell Health (3) · Meyer Children's Hospital IRCCS (2) · Ain Shams University (1) · Centre Hospitalier Universitaire de Nice (1) · Children's Hospital of Philadelphia (1) · Children's National Research Institute (1) · Chulalongkorn University (1) · Emory University (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · Istanbul University (1) · Mansoura University (1) · Mario Negri Institute for Pharmacological Research (1) · Medical University of Bialystok (1) · Muhammad Aamir Latif (1) · Nanjing University School of Medicine (1)
United States (9) · Italy (4) · Egypt (3) · Pakistan (3) · China (2) · France (1) · Germany (1) · Ireland (1) · Mexico (1) · Poland (1) · Russia (1) · Spain (1) · Thailand (1) · Turkey (Türkiye) (1)
Afsheen Asghar, FCPS (1) · Alicja Rydzewska-Rosolowska, MD (1) · Asha Moudgil, MD (1) · Berna Yelken, MD (1) · Chia-shi Wang, MD, MS (1) · Christine Sethna, MD (1) · Donal Sexton, MB BCh BAO BSc, MRCPI, MD, PhD (1) · Fawzia Abusaad, Prof (1) · Giuseppe Remuzzi, MD (1) · Halil Yazici, MD (1) · Kristen Sgambat, MS, RD (1) · Matthias Kretzler, MD (1) · Mehmet S Sever, Prof MD (1) · Michelle Denburg, MD, MSCE (1) · Rabia Saleem, FCPS (1)
PMID 38724717, PMID 24707402, PMID 28914167, PMID 29531933, PMID 30999886, PMID 32272901, PMID 32866504, PMID 33206054, PMID 35078538, PMID 37090998, PMID 40993587
R01DK131091 (2), K23DK093556 (1), K23DK118189 (1), R01DK141114 (1), U54DK083912 (1)