5 recruiting, 4 unknown, 3 completed, 1 active not recruiting. 15 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 15 | Recruiting 5, Unknown 4, Completed 3, Active not recruiting 1, Not yet recruiting 1, Suspended 1 |
| Phase 2 | 3 | Completed 1, Recruiting 1, Unknown 1 |
Follow Neoadjuvant Chemotherapy: new trials by email Literature Review of Neoadjuvant Chemotherapy trials Research Report on Neoadjuvant Chemotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC Megestrol Acetate - Neoadjuvant Chemotherapy, Weight Loss | Phase 3 | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 60 | 2025-11-11 | 2025-12-12 |
| Standard or Prolonged Neoadjuvant Chemotherapy Before Surgery for BR/LAPC FOLFIRINOX or gemcitabine-nab-paclitaxel - Locally Advanced Pancreatic Adenocarcinoma, Borderline Resectable Pancreatic Carcinoma | Phase 3 | Recruiting | Sahlgrenska University Hospital | 432 | 2023-10-18 | 2024-12-03 |
| NeoFOL-R Trial (Perioperative Versus Adjuvnat FOLFIRINOX in Resectable Pancreatic Cancer) Folfirinox - Resectable Pancreatic Cancer, Neoadjuvant Chemotherapy | Phase 3 | Recruiting | Seoul National University Hospital | 609 | 2023-04-01 | 2024-11-27 |
| Fasting Mimicking Diet Program to ImpRovE ChemoTherapy in Hormone Receptor Postive (HR+), HER2- Breast Cancer Fasting Mimicking diet program - Fasting Mimicking Diet, HER2-negative Breast Cancer | Phase 3 | Suspended | Leiden University Medical Center | 10 | 2023-03-17 | 2023-11-22 |
| Neoadjuvant Chemotherapy Followed by Chemoradiation Versus Chemoradiation for Stage IIIC Cervical Cancer Patients: A Randomized Phase III Trial Albumin-Bound Paclitaxel, Carboplatin - Cervical Cancer, Neoadjuvant Chemotherapy | Phase 3 | Recruiting | Sun Yat-sen University | 280 | 2022-03-14 | 2022-05-10 |
| Dragon III-Phase 3: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric Cancer Chemotherapy - Gastric Cancer, Neoadjuvant Chemotherapy | Phase 3 | Not yet recruiting | Ruijin Hospital | 246 | 2021-09-01 | 2021-07-19 |
| Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer Capox chemotherapy - Rectal Cancer, Neoadjuvant Chemotherapy | Phase 3 | Active not recruiting | West China Hospital | 554 | 2021-08-26 | 2025-07-11 |
| Paclitaxel i.v. Plus Cisplatin i.p for NACT in Patients With Advanced Ovarian Cancer cisplatin i.p. - Epithelial Carcinoma, Ovarian, Neoadjuvant Chemotherapy | Phase 3 | Unknown | West China Second University Hospital | 50 | 2021-08-04 | 2021-08-10 |
| Study of Neoadjuvant Chemotherapy Versus Definite Concurrent Chemoradiotherapy for Locally Advanced Bulk Cervical Cancer gemcitabine and cisplatin - Cervical Cancer, Neoadjuvant Chemotherapy | Phase 3 | Unknown | Chuangzhen Chen | 290 | 2021-07-01 | 2024-02-06 |
| Efficacy and Safety of Dose-dense Chemotherapy (ddEC-ddP) for Neoadjuvant Chemotherapy of HER2-negative Breast Cancer Epirubicin, Cyclophosphamid, Docetaxel - HER2-negative Breast Cancer, Neoadjuvant Chemotherapy | Phase 2 / Phase 3 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 260 | 2020-09-20 | 2021-08-12 |
| A Multicenter, Prospective, Phase III Randomized Controlled Clinical Study for the Treatment of N2-3 Nasopharyngeal Carcinoma Patients 4 cycles of Neoadjuvant Chemotherapy With Definitive Radiotherapy, 3 cycles of Neoadjuvant Chemotherapy With concurrent chemoradiotherapy - Nasopharyngeal Carcinoma, Neoadjuvant Chemotherapy | Phase 3 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 246 | 2019-08-01 | 2020-05-12 |
| Sequential Use of AG and mFOLFIRINOX as Neoadjuvant Chemotherapy for Resectable Pancreatic Cancer AG regimen, mFolfirinox - Pancreatic Adenocarcinoma Resectable, Neoadjuvant Chemotherapy | Phase 3 | Completed | Second Affiliated Hospital, Zhejiang University, School of Medicine | 324 | 2018-10-20 | 2025-05-13 |
| Pathological Complete Response Rate in Locally Advanced Breast Cancer With FEC, EC-T, or TC as Neoadjuvant Chemotherapy Epirubicin, Fluorouracil, Docetaxel - Breast Cancer, Pathological Complete Response | Phase 2 / Phase 3 | Unknown | Zhiyong Yu | 200 | 2017-11-27 | 2017-11-21 |
| Melatonin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response in Locally Advanced Oral Squamous Cell Carcinoma Melatonin 20 MG Oral Capsule, Placebo oral capsule - Oral Squamous Cell Carcinoma, Neoadjuvant Chemotherapy | Phase 3 | Completed | Universitas Indonesia | 50 | 2017-07-04 | 2019-12-09 |
| DIetary REstriction as an Adjunct to Neoadjuvant ChemoTherapy for HER2 Negative Breast Cancer Fasting mimicking diet - Fasting Mimicking Diet, Breast Cancer | Phase 2 / Phase 3 | Completed | Leiden University Medical Center | 131 | 2014-02-01 | 2019-10-24 |
Breast Neoplasms (2) · Pancreatic Neoplasms (2) · Uterine Cervical Neoplasms (2) · Adenocarcinoma (1) · Carcinoma, Ovarian Epithelial (1) · Nasopharyngeal Carcinoma (1) · Rectal Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1) · Stomach Neoplasms (1) · Weight Loss (1)
Neoplasms (11) · Neoplasms by Site (11) · Carcinoma (4) · Digestive System Diseases (4) · Digestive System Neoplasms (4) · Neoplasms by Histologic Type (4) · Neoplasms, Glandular and Epithelial (4) · Endocrine Gland Neoplasms (3) · Endocrine System Diseases (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genital Diseases (3) · Genital Diseases, Female (3) · Genital Neoplasms, Female (3) · Urogenital Diseases (3)
Cyclophosphamide (2) · Docetaxel (2) · Epirubicin (2) · Fluorouracil (2) · Gemcitabine (2) · folfirinox (2) · 130-nm albumin-bound paclitaxel (1) · Albumin-Bound Paclitaxel (1) · Carboplatin (1) · Chemoradiotherapy (1) · Cisplatin (1) · Doxorubicin (1) · Drug Therapy (1) · Folic Acid (1) · Irinotecan (1)
Second Affiliated Hospital, Zhejiang University, School of Medicine (3) · Leiden University Medical Center (2) · Chuangzhen Chen (1) · Ruijin Hospital (1) · Sahlgrenska University Hospital (1) · Seoul National University Hospital (1) · Sixth Affiliated Hospital, Sun Yat-sen University (1) · Sun Yat-sen University (1) · Universitas Indonesia (1) · West China Hospital (1) · West China Second University Hospital (1) · Zhiyong Yu (1)
China (9) · Netherlands (2) · Indonesia (1) · South Korea (1) · Sweden (1)
Birendra K Sah, PH D (1) · Chen Li, PH D (1) · Chuangzhen Chen, MD (1) · Diani Kartini, MD (1) · Elena Rangelova, PhD (1) · Hanno Pijl, MD PhD (1) · Judith R Kroep, MD, PhD (1) · Judith R Kroep, PhD (1) · Jun Huang, PhD. (1) · Qichun Wei (1) · Tingbo Liang, MD PhD (1) · Wooil Kwon (1) · Xiaoshan Cao, MD (1) · Yiding Chen (1)