27 unknown, 13 recruiting, 10 completed, 8 not yet recruiting. 17 Phase 2, 15 Phase 3, 11 Not applicable, 2 Early Phase 1, 1 Phase 4.
Follow Neoadjuvant Chemotherapy: new trials by email Literature Review of Neoadjuvant Chemotherapy trials Research Report on Neoadjuvant Chemotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ultrasound Monitoring of Clipped Lymph Nodes to Predict Axillary Response After Chemotherapy in Breast Cancer Breast Cancer, Axillary Lymph Node Metastasis | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 150 | 2026-05-20 | 2026-05-19 | |
| Neoadjuvant CAPEOX Versus Upfront Surgery for Locally Advanced Colon Cancer With Elevated CEA: A Single-Center, Open-Label, Randomized Controlled Trial ctDNA-Based Molecular Residual Disease (MRD) Monitoring and Immunoscore Assessment, Neoadjuvant Chemotherapy, Adjuvant chemotherapy - Minimal Residual Disease, Immunoscore | Not applicable | Not yet recruiting | Sun Yat-sen University | 100 | 2026-02-24 | 2026-02-17 |
| Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in IBC SLN identification using technetium-99m, SLN intra-operatory identification with radioguided surgery, Axillary Limph Node Dissection (ALND) - Invasive Breast Carcinoma, Sentinel Lymph Node Biopsy (SLNB) | Not applicable | Recruiting | European Institute of Oncology | 75 | 2025-12-12 | 2026-01-06 |
| Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC Megestrol Acetate - Neoadjuvant Chemotherapy, Weight Loss | Phase 3 | Recruiting | Sixth Affiliated Hospital, Sun Yat-sen University | 60 | 2025-11-11 | 2025-12-12 |
| Evaluation of Seismocardiography(SCG) for Assessing Fitness and Predicting Outcomes in Oesophageal Cancer Surgery Seismofit - Oesophageal Cancer, Oesophageal Adenocarcinoma | Recruiting | Guy's and St Thomas' NHS Foundation Trust | 164 | 2025-10-01 | 2026-09-14 | |
| Evaluating Bemotuzumab to Improve the Efficacy of Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer (TNBC) nab-paclitaxel, carboplatin, and bemotuzumab, epirubicin, cyclophosphamide, and bemotuzumab - Triple-Negative Breast Cancer (TNBC), Neoadjuvant Chemotherapy | Not applicable | Not yet recruiting | Zhejiang Provincial People's Hospital | 55 | 2025-09-01 | 2025-05-22 |
| Envafolimab Combined With Neoadjuvant Chemotherapy Treat Stage IIb Resectable Osteosarcoma Patients Envafolimab and neoadjuvant chemotherapy - Osteosarcoma, Neoadjuvant Therapy | Phase 2 | Not yet recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 23 | 2025-08-25 | 2025-08-27 |
| The Better, Harder, Faster, Stronger Study data collection - Frailty at Older Adults, Ovarian Cancer | Recruiting | Wake Forest University Health Sciences | 35 | 2025-07-28 | 2026-07-15 | |
| Fasting-Mimicking Diet as an Adjunct to Neoadjuvant Chemotherapy for Hormone-Receptor-Positive Breast Cancer Fasting-mimicking diet (FMD) Group - Fasting-Mimicking Diet, Breast Cancer | Not applicable | Not yet recruiting | Guangdong Provincial People's Hospital | 45 | 2025-07-12 | 2025-07-22 |
| The Effect of Neoadjuvant Chemotherapy on Physical Functions No intervention will be performed as part of this study. However, regardless of the study, all participants will receive neoadjuvant chemotherapy. - Breast Cancer, Neoadjuvant Chemotherapy | Completed | ATİYE KAŞ ÖZDEMİR | 67 | 2025-01-08 | 2026-02-20 | |
| Efficacy and Safety of Neoadjuvant Sintilimab Plus FLOT Versus Sintilimab Plus SOX Phase II Clinical Trial for Patients With Locally Advanced Gastric Cancer SOX+Sintilimab, FLOT+Sintilimab - Neoadjuvant Chemotherapy, Sintilimab | Phase 2 | Not yet recruiting | Xijing Hospital | 200 | 2024-12-01 | 2024-10-10 |
| Effect of Neoadjuvant Chemotherapy on Cardiac Function of Perioperative Patients With Breast Cancer and New Strategies for Anesthesia Deoxyadrenaline, normal saline - Breast Cancer, Neoadjuvant Chemotherapy | Phase 4 | Unknown | Fujian Medical University Union Hospital | 496 | 2024-08-01 | 2025-03-04 |
| Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer CEDM, CEDBT, Omnipaque 350mgI/mL Solution for Injection - Breast Cancer, Locally Advanced Breast Cancer | Early Phase 1 | Recruiting | Alison Stopeck | 30 | 2024-03-06 | 2026-01-15 |
| Irinotecan Liposome for Resectable Pancreatic Cancer With or Without Addebelizumab irinotecan liposome + oxaliplatin + 5-FU / LV, Adebellizumab - Neoadjuvant Chemotherapy, Resectable Pancreatic Cancer | Phase 2 | Not yet recruiting | Zhejiang University | 180 | 2024-01-20 | 2023-12-15 |
| Bladder Cancer Staging and Prediction of New Adjuvant Chemotherapy Efficacy Based on Deep Learning and Transfer Learning in Ultrasound-Magnetic Resonance-Pathology Multimodal Multiscale Risk Stratification - Bladder Cancer, Staging | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 480 | 2024-01-01 | 2025-07-03 | |
| Vabb After Neoadjuvant Therapy to Avoid Surgery-pCR to Avoid Breast Surgery Omission of surgical treatment - Breast Cancer, Triple Negative Breast Cancer | Not applicable | Recruiting | European Institute of Oncology | 77 | 2023-12-11 | 2024-02-28 |
| Organoids Based Drug Sensitivity in Neoadjuvant Chemotherapy of Breast Cancer Biopsy - Organoids, Breast Cancer | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 58 | 2023-12-06 | 2025-01-07 | |
| Appraisal of the Modified Cancer Cachexia Index in Locally Advanced Gastric Cancer Patients Undergoing Neoadjuvant Chemotherapy Gastric Cancer, Neoadjuvant Chemotherapy | Completed | Fujian Medical University | 600 | 2023-12-01 | 2024-11-14 | |
| New Prognostic Index for Neoadjuvant Chemotherapy Outcome in Patients With Advanced High-grade Serous Ovarian Cancer CRS scoring, Routine blood laboratory testing before treatment - Ovarian Cancer, Neoadjuvant Chemotherapy | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 465 | 2023-11-01 | 2023-11-07 | |
| Standard or Prolonged Neoadjuvant Chemotherapy Before Surgery for BR/LAPC FOLFIRINOX or gemcitabine-nab-paclitaxel - Locally Advanced Pancreatic Adenocarcinoma, Borderline Resectable Pancreatic Carcinoma | Phase 3 | Recruiting | Sahlgrenska University Hospital | 432 | 2023-10-18 | 2024-12-03 |
Showing 20 of 64. Sign in to see all of them.
Breast Neoplasms (17) · Stomach Neoplasms (6) · Ovarian Neoplasms (4) · Pancreatic Neoplasms (4) · Triple Negative Breast Neoplasms (4) · Uterine Cervical Neoplasms (3) · Bites and Stings (2) · Colorectal Neoplasms (2) · Motor Activity (2) · Squamous Cell Carcinoma of Head and Neck (2) · Adenocarcinoma (1) · Adenocarcinoma Of Esophagus (1) · Carcinoma, Ovarian Epithelial (1) · Carcinoma, Transitional Cell (1) · Cognitive Dysfunction (1)
Neoplasms (49) · Neoplasms by Site (46) · Breast Diseases (19) · Skin Diseases (19) · Skin and Connective Tissue Diseases (19) · Digestive System Diseases (15) · Digestive System Neoplasms (15) · Gastrointestinal Diseases (11) · Gastrointestinal Neoplasms (11) · Endocrine Gland Neoplasms (9) · Endocrine System Diseases (9) · Female Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (9) · Urogenital Diseases (9) · Urogenital Neoplasms (9)
Neoadjuvant Therapy (6) · Epirubicin (5) · Fluorouracil (5) · Cyclophosphamide (4) · Oxaliplatin (4) · Carboplatin (3) · Docetaxel (3) · Paclitaxel (3) · 130-nm albumin-bound paclitaxel (2) · Albumin-Bound Paclitaxel (2) · Chemoradiotherapy (2) · Cisplatin (2) · Doxorubicin (2) · Gemcitabine (2) · Irinotecan (2)
Second Affiliated Hospital, Zhejiang University, School of Medicine (5) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (5) · Sun Yat-sen University (3) · Beijing Chao Yang Hospital (2) · European Institute of Oncology (2) · Leiden University Medical Center (2) · Peking University (2) · Tianjin Medical University Cancer Institute and Hospital (2) · West China Hospital (2) · Zhejiang Provincial People's Hospital (2) · Zhiyong Yu (2) · ATİYE KAŞ ÖZDEMİR (1) · Acıbadem Atunizade Hospital (1) · Alison Stopeck (1) · Chinese Academy of Medical Sciences (1)
China (38) · South Korea (4) · United States (3) · Italy (2) · Netherlands (2) · Turkey (Türkiye) (2) · Croatia (1) · Egypt (1) · Indonesia (1) · Sweden (1) · Taiwan (1) · United Kingdom (1)
Alison Stopeck, MD (1) · Ana Car Peterko (1) · Andrew Davies, MD FRCS (1) · Anna Kuan-Celarier, MD (1) · Aysun Isiklar, M.D. (1) · Binghe Xu, MD (1) · Birendra K Sah, PH D (1) · Chang-Ming Huang, M.D. FACS (1) · Chen Li, PH D (1) · Chuangzhen Chen, MD (1) · Chuanmiao Xie, PhD (1) · Diani Kartini, MD (1) · Elena Rangelova, PhD (1) · Elisabetta Rossi, MD (1) · Emma Barber, MD, MS (1)
PMID 11352955, PMID 11600601, PMID 12586807, PMID 12771730, PMID 12944571, PMID 15939524, PMID 16034041, PMID 21502557, PMID 24373477, PMID 24472710, PMID 24669010, PMID 24821881, PMID 24821883, PMID 25257030, PMID 26205531, PMID 26421586, PMID 27053504, PMID 28625005, PMID 29329894, PMID 30506533, PMID 31046081, PMID 32372215, PMID 32576828, PMID 33179154, PMID 33403051, PMID 35969358, PMID 36056951, PMID 36720570, PMID 36983157, PMID 37312165, PMID 39725764, PMID 39909529, PMID 40281451