20 completed. 20 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 20 | Completed 20 |
| Phase 1 | 1 | Completed 1 |
Follow Morphological and Microscopic Findings: new trials by email Literature Review of Morphological and Microscopic Findings trials Research Report on Morphological and Microscopic Findings
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate a New Method to Detect Residual Tumours During Surgery for Prostate Cancer Using Confocal Microscopy NeuroSAFE procedure, LaserSAFE procedure - Prostate Cancer | Phase 1 / Phase 2 | Completed | University College, London | 21 | 2024-05-15 | 2025-01-10 |
| Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (isSCC) Aminolevulinic Acid 20% Topical Solution with Blue Light - Facial Cutaneous Squamous Cell Carcinoma in Situ | Phase 2 | Completed | The Center for Clinical and Cosmetic Research | 32 | 2023-08-08 | 2025-02-12 |
| A Study to Evaluate Safety, Efficacy of Intralesional Injection of STP705 in Patients With isSCC STP705, Placebo Saline - Squamous Cell Carcinoma in Situ | Phase 2 | Completed | Sirnaomics | 44 | 2021-05-18 | 2024-03-18 |
| VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions Electroporation, HPV DNA Plasmids Therapeutic Vaccine VGX-3100, Laboratory Biomarker Analysis - Anal Intraepithelial Neoplasia, High Grade Squamous Intraepithelial Neoplasia | Phase 2 | Completed | AIDS Malignancy Consortium | 44 | 2018-09-21 | 2026-07-08 |
| VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2 VGX-3100, CELLECTRA™ 5PSP - Anal Neoplasm | Phase 2 | Completed | Inovio Pharmaceuticals | 23 | 2018-05-15 | 2023-07-14 |
| Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer Simvastatin 40mg, Placebo oral capsule - Breast Cancer, Chemotherapy Effect | Phase 2 | Completed | Universitas Indonesia | 60 | 2018-01-15 | 2020-06-05 |
| Aminolaevulinic Acid Photodynamic Therapy for HPV+ Low Grade Cervical Intraepithelial Neoplasia (LSIL;CIN1) Aminolaevulinic acid, Placebo - Cervical Intraepithelial Neoplasia, Low-Grade Squamous Intraepithelial Lesions | Phase 2 | Completed | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | 60 | 2016-03-22 | 2019-07-08 |
| A Clinical Trial of PepCan to Two Therapy Arms for Treating Cervical High-Grade Squamous Intraepithelial Lesions PepCan, Candin® - Cervical Intraepithelial Neoplasia | Phase 2 | Completed | University of Arkansas | 81 | 2015-11-30 | 2023-12-18 |
| Probiotic Implementation as Help in Solving Vaginal Infections Lactobacillus rhamnosus BMX 54 - Vaginal Infection, ASC-US | Phase 2 | Completed | University of Roma La Sapienza | 117 | 2015-02-01 | 2017-12-13 |
| A Single-arm Phase II Study of Post-Transoral Robotic Surgery (TORS) Alone to the Primary Tumor Site and Selective Neck Dissection (SND) Followed by Adjuvant Radiation Therapy (+/- Chemotherapy) to the Regional Nodes for Advanced Stage, Human Papilloma Virus (HPV) Positive, Oropharyngeal Cancer TORS, Adjuvant Radiation Therapy - Oropharyngeal Cancer | Phase 2 | Completed | Abramson Cancer Center at Penn Medicine | 60 | 2014-02-01 | 2019-11-21 |
| Study of the ICG Distribution in the Margins of Breast Cancer After Tumorectomy Indocyanine Green - Breast Cancer | Phase 2 | Completed | Jules Bordet Institute | 20 | 2014-01-01 | 2023-12-15 |
| A Prolongation of a Clinical Study to Evaluate the Efficacy of an Aqueous Gel Containing 2% (w/w) of Cidofovir, Directly Applied on the Cervix Exhibiting High Grade Squamous Intraepithelial Lesions. Cidofovir - High Grade Cervical Epithelial Neoplasia (CIN2+) | Phase 2 | Completed | Brugmann University Hospital | 36 | 2013-02-01 | 2016-11-30 |
| Study of GSK2132231A Antigen-Specific Cancer Immunotherapeutic in Patients With Inoperable Metastatic Cutaneous Melanoma Immunotherapeutic GSK2132231A - Melanoma | Phase 2 | Completed | GlaxoSmithKline | 24 | 2009-05-19 | 2021-04-08 |
| Safety and Efficacy of Bevacizumab Plus RAD001 Versus Interferon Alfa-2a and Bevacizumab for the First-line Treatment in Adult Patients With Kidney Cancer RAD001(everolimus), interferon alfa-2a, bevacizumab - Carcinoma, Adenocarcinoma | Phase 2 | Completed | Novartis Pharmaceuticals | 365 | 2008-11-12 | 2017-03-20 |
| Human Papillomavirus Vaccine Therapy in Treating Men With HIV-1 Infection Gardasil - Infection, Precancerous Condition | Phase 2 | Completed | AIDS Malignancy Consortium | 112 | 2007-11-01 | 2023-11-14 |
| A Two-Stage Phase 2 Study Of A-007 Topical Gel in High-Grade Squamous Intraepithelial Lesions (HSIL) A-007 - Cervical Intraepithelial Neoplasia, Uterine Cervical Dysplasia | Phase 2 | Completed | Tigris Pharmaceuticals | 11 | 2007-11-01 | 2009-05-22 |
| Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus cidofovir, DNA methylation analysis, gene expression analysis - Anal Cancer, Precancerous Condition | Phase 2 | Completed | AIDS Malignancy Consortium | 33 | 2007-09-01 | 2015-12-21 |
| Folic Acid Clinical Trial for the Prevention of Cervical Cancer folic acid, placebo - Cervical Cancer, Precancerous Condition | Phase 2 | Completed | University of Alabama at Birmingham | 368 | 2007-03-01 | 2015-10-08 |
| Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix placebo, A007 - Cervical Intraepithelial Neoplasia, Uterine Cervical Dysplasia | Phase 2 | Completed | Tigris Pharmaceuticals | 147 | 2006-01-01 | 2010-10-11 |
| SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells HspE7, placebo, laboratory biomarker analysis - Atypical Squamous Cells of Undetermined Significance, Cervical Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 139 | 2004-09-01 | 2013-06-03 |
Squamous Intraepithelial Lesions (13) · Atypical Squamous Cells of the Cervix (5) · Margins of Excision (5) · Uterine Cervical Dysplasia (5) · Papillomavirus Infections (3) · Precancerous Conditions (3) · Anus Neoplasms (2) · Breast Neoplasms (2) · Uterine Cervical Neoplasms (2) · Adenocarcinoma (1) · Candidiasis, Vulvovaginal (1) · Carcinoma (1) · Carcinoma, Renal Cell (1) · Carcinoma, Squamous Cell (1) · HIV Seropositivity (1)
Pathological Conditions, Signs and Symptoms (20) · Neoplasms (17) · Urogenital Diseases (12) · Genital Diseases (11) · Neoplasms by Site (11) · Female Urogenital Diseases (10) · Female Urogenital Diseases and Pregnancy Complications (10) · Genital Diseases, Female (9) · Uterine Cervical Diseases (9) · Uterine Diseases (9) · Precancerous Conditions (7) · Communicable Diseases (4) · Infections (4) · Sexually Transmitted Diseases (4)
4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (2) · Cidofovir (2) · VGX-3100 (2) · 5-aminolaevulinic acid-n-pentylester (1) · Aminolevulinic Acid (1) · Bevacizumab (1) · Biopsy (1) · Blue Light (1) · DNA Methylation (1) · Electroporation (1) · Electroporation Therapies (1) · Everolimus (1) · Folic Acid (1) · Gene Expression Profiling (1) · Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 (1)
AIDS Malignancy Consortium (3) · Tigris Pharmaceuticals (2) · Abramson Cancer Center at Penn Medicine (1) · Brugmann University Hospital (1) · GlaxoSmithKline (1) · Inovio Pharmaceuticals (1) · Jules Bordet Institute (1) · National Cancer Institute (NCI) (1) · Novartis Pharmaceuticals (1) · Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. (1) · Sirnaomics (1) · The Center for Clinical and Cosmetic Research (1) · Universitas Indonesia (1) · University College, London (1) · University of Alabama at Birmingham (1)
United States (13) · Belgium (4) · France (2) · United Kingdom (2) · Brazil (1) · Canada (1) · China (1) · Czechia (1) · Egypt (1) · Germany (1) · Hong Kong (1) · Hungary (1) · Indonesia (1) · Italy (1) · Netherlands (1)
Cynthia J Goldberg, MD (2) · Joel Palefsky, MD (2) · Keith A Aqua, MD (2) · Mark H Einstein, MD (2) · Robert Pfeffer, MD (2) · Alexander Lin, MD (1) · Allan T Sawyer, MD (1) · Ana Eduardo, MD (1) · Baju Adji (1) · Beihua Kong, MD (1) · Brenda LaTowsky, MD (1) · Brian Jiang, MD (1) · Catherine Vanpachterbeke, MD (1) · Chandrika J. Piyathilake, PhD, MPH (1)
PMID 20812850, PMID 23032420, PMID 25851632, PMID 29304768, PMID 31785337, PMID 34907980, PMID 37146227, PMID 41309506
2008 (2), U01CA121947 (2), UM1CA121947 (1)