6 recruiting, 3 active not recruiting. 6 Phase 1, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Recruiting 4, Active not recruiting 2 |
| Phase 2 | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Metastatic Malignant Neoplasm in the Peritoneum: new trials by email Literature Review of Metastatic Malignant Neoplasm in the Peritoneum trials Research Report on Metastatic Malignant Neoplasm in the Peritoneum
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial Bevacizumab, Biopsy Procedure, Biospecimen Collection - Metastatic Appendix Carcinoma, Metastatic Colorectal Carcinoma | Phase 3 | Recruiting | City of Hope Medical Center | 129 | 2027-01-04 | 2026-11-05 |
| Nab-Paclitaxel PIPAC in Combination With Paclitaxel and Ramucirumab for the Treatment of Stomach Cancer With Peritoneal Metastases Biopsy, Biospecimen Collection, Computed Tomography - Clinical Stage IVB Gastric Cancer AJCC v8, Metastatic Gastric Adenocarcinoma | Phase 1 | Recruiting | City of Hope Medical Center | 30 | 2025-10-29 | 2025-11-10 |
| Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer Biopsy, Biospecimen Collection, Computed Tomography - Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Peritoneum | Phase 1 | Active not recruiting | Arjun Mittra | 9 | 2024-12-31 | 2026-10-09 |
| Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis Cisplatin, Hyperthermic Intraperitoneal Chemotherapy, Nab-paclitaxel - Metastatic Pancreatic Carcinoma, Stage IV Pancreatic Cancer AJCC v8 | Phase 2 | Active not recruiting | Mayo Clinic | 40 | 2024-02-15 | 2026-10-15 |
| Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis Aldesleukin, Biopsy Procedure, Biospecimen Collection - Clinical Stage IV Gastric Cancer AJCC v8, Gastric Adenocarcinoma | Phase 1 | Active not recruiting | Mayo Clinic | 15 | 2023-11-29 | 2026-07-01 |
| Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Treatment of Gastric Cancer With Limited Peritoneal Metastasis, ROBO-CHIP Study Cisplatin, Computed Tomography, Gastrectomy - Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma | Phase 2 | Recruiting | Mayo Clinic | 40 | 2023-04-20 | 2026-04-08 |
| Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases Cisplatin, Gemcitabine, Nab-paclitaxel - Distal Bile Duct Adenocarcinoma, Gallbladder Carcinoma | Phase 1 | Recruiting | City of Hope Medical Center | 12 | 2022-09-19 | 2026-08-03 |
| Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) Associated With Systemic Chemotherapy in Women With Advanced Ovarian Cancer Combined PIPAC / IV chemotherapy treatment - Metastatic Ovarian Carcinoma, Peritoneal Carcinomatosis | Phase 1 | Recruiting | Hospices Civils de Lyon | 15 | 2021-07-30 | 2026-10-06 |
| PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer Biopsy, Cisplatin, Doxorubicin - Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8 | Phase 1 | Recruiting | City of Hope Medical Center | 49 | 2020-08-21 | 2026-08-26 |
Colorectal Neoplasms (3) · Appendiceal Neoplasms (2) · Ovarian Neoplasms (2) · Peritoneal Neoplasms (2) · Stomach Neoplasms (2) · Carcinoma, Ovarian Epithelial (1) · Cholangiocarcinoma (1) · Fallopian Tube Neoplasms (1) · Gallbladder Neoplasms (1) · Neoplasm Metastasis (1) · Pancreatic Neoplasms (1) · Uterine Neoplasms (1)
Digestive System Diseases (7) · Digestive System Neoplasms (7) · Neoplasms (7) · Neoplasms by Site (7) · Gastrointestinal Diseases (4) · Gastrointestinal Neoplasms (4) · Colonic Diseases (3) · Endocrine Gland Neoplasms (3) · Endocrine System Diseases (3) · Intestinal Diseases (3) · Intestinal Neoplasms (3) · Rectal Diseases (3) · Abdominal Neoplasms (2) · Adnexal Diseases (2) · Carcinoma (2)
Magnetic Resonance Spectroscopy (6) · Biopsy (5) · 1,2-diaminocyclohexaneplatinum II citrate (4) · Albumin-Bound Paclitaxel (4) · Cisplatin (4) · Fluorouracil (4) · Platinum (4) · Specimen Handling (4) · Taxes (4) · dehydroftorafur (4) · 130-nm albumin-bound paclitaxel (3) · Hyperthermic Intraperitoneal Chemotherapy (3) · Leucovorin (3) · Oxaliplatin (3) · Irinotecan (2)
City of Hope Medical Center (4) · Mayo Clinic (3) · Arjun Mittra (1) · Hospices Civils de Lyon (1)
United States (8) · France (1)
Mustafa Raoof, MD (2) · Arjun Mittra, MD (1) · Cornelius A. Thiels, DO, MBA (1) · Daneng Li, MD (1) · Mustafa Raoof (1) · Thanh H Dellinger, MD (1) · Travis E Grotz, MD (1) · Travis E. Grotz, MD (1) · Yanghee Woo (1)
P30CA033572 (4), R21CA282536 (1)