20 completed, 5 not yet recruiting, 5 recruiting, 2 unknown. 24 Not applicable, 3 Phase 4, 2 Phase 1, 2 Phase 2, 1 Early Phase 1.
Follow Menstrual Pain: new trials by email Literature Review of Menstrual Pain trials Research Report on Menstrual Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Transcutaneous Cervical Vagus Nerve Stimulation for Primary Dysmenorrhea Transcutaneous Cervical Vagus Nerve Stimulation, Sham Transcutaneous Cervical Vagus Nerve Stimulation - Primary Dysmenorrhea (PD), Menstrual Pain | Not applicable | Not yet recruiting | Sinop University | 70 | 2026-10-31 | 2026-10-19 |
| Vaginal Sildenafil for Primary Dysmenorrhea Sildenafil citrate vaginal suppository - Dysmenorrhea, Menstrual Pain | Phase 1 | Not yet recruiting | Kevin Hellman | 10 | 2026-10-01 | 2026-09-25 |
| Effect of Virtual Reality on Pain and Anxiety in Women With Dysmenorrhea Virtual Reality - Primary Dysmenorrhea, Menstrual Pain | Not applicable | Not yet recruiting | Tokat Gaziosmanpasa University | 68 | 2026-09-30 | 2026-10-07 |
| High-Intensity Interval Training and Menstrual Health Experience in Primary Dysmenorrhea. Supervised Online HIIT Program, Menstrual Health Workshop - Dysmenorrhea Primary, Menstrual Pain | Not applicable | Recruiting | University of Alcala | 60 | 2026-02-18 | 2026-04-21 |
| Self-Acupressure for Primary Dysmenorrhea and Premenstrual Symptoms Self-Acupressure, Sham Self-Acupressure - Primary Dysmenorrhea, Premenstrual Syndrome | Not applicable | Recruiting | Nigde Omer Halisdemir University | 120 | 2026-02-15 | 2026-08-24 |
| The Good Pain Consultation in Endometriosis. pain consultation, biopsychosocial pain education + usual care, Usual Care - Pelvic Pain Syndrome, Endometriosis | Not applicable | Recruiting | Sorlandet Hospital HF | 110 | 2025-11-01 | 2026-04-28 |
| Abdominal Muscle Strengthening for Menstrual Symptoms in Primary Dysmenorrhea Abdominal Muscle Strengthening Exercises with Stabilizer Pressure Biofeedback - Menstrual Pain, Menstrual Disorders | Not applicable | Not yet recruiting | Bulent Ecevit University | 58 | 2025-08-13 | 2025-08-19 |
| An Open-Label Study to Evaluate the Effect of Elix Cycle Balance & Elix Daily Harmony on Fibroid-related Symptoms Elix Daily Harmony - Uterine Fibroids, Leiomyoma | Not applicable | Recruiting | Zenchi, Inc. | 42 | 2025-08-01 | 2025-09-12 |
| A Research Study Exploring How Musculoskeletal Function and the Autonomic Nervous System Relate to Visceral Pain in Women With and Without Dysmenorrhea (Painful Periods). Visceral Pain Stimulus - Dysmenorrhea, Dysmenorrhea Primary | Not applicable | Recruiting | Azusa Pacific University | 60 | 2025-08-01 | 2025-10-07 |
| Effectiveness of Post Isometric Relaxation Technique Versus Simple Stretching Exercises for Pain and Physical Activity in Young Females With Primary Dysmenorrhea in Peshawar Post-Isometric Relaxation (PIR), Simple Stretching Exercises (SSE) - Dysmenorrhea, Menstrual Pain | Not applicable | Completed | Khyber Medical University Peshawar | 44 | 2025-07-01 | 2026-01-05 |
| Effect of Myofascial Release on Menstrual Pain Post Caesarean Section stretching exrcise, myofascial release - Menstrual Pain | Not applicable | Not yet recruiting | Cairo University | 58 | 2025-04-30 | 2025-04-30 |
| A Clinical Study to Assess the Effect of a Dietary Supplement on Menstrual Cycle Symptoms DITTO Cycle Supplement - Premenstrual Syndrome, Menstrual Pain | Not applicable | Completed | Muse Nutrition Ltd | 40 | 2025-02-01 | 2026-08-17 |
| Effects of Pilates Exercises Applied With Face-to-Face and Telerehabilitation on Menstrual Pain Pilates Exercises With Face-to-Face, Pilates Exercises With Telerehabilitation - Menstrual Pain | Not applicable | Completed | Halic University | 20 | 2024-06-10 | 2025-03-14 |
| The Effectiveness of an Intervention of Fresh Strawberries on Menstrual Pain and Menstrual Distress Strawberry Intervention - Primary Dysmenorrhea, Menstrual Pain | Not applicable | Completed | Cynthia del Rocío Márquez Beltrán | 64 | 2024-04-02 | 2024-08-01 |
| Non-Steroidal Anti-Inflammatory Drug (NSAID) Response and Central Sensitization of Pain in Women With Dysmenorrhea Sodium Naproxen, Placebo - Dysmenorrhea, Menstrual Pain | Phase 4 | Completed | Mclean Hospital | 70 | 2024-03-25 | 2026-09-22 |
| Effect of a Calisthenic Exercises on Premenstrual Symptoms Calisthenic home exercise programs - Menstrual Pain | Not applicable | Completed | Halic University | 30 | 2024-02-15 | 2024-07-31 |
| Quality of Life Variations Among Adolescent Females Following Virtual Reality Games Approach Aerobic exercise, Diet Advice, Virtual reality exercise - Obesity and Obesity-related Medical Conditions, Menstrual Pain | Not applicable | Completed | Mina Atef Georgui Elias | 100 | 2023-10-01 | 2024-12-05 |
| Effectiveness of PEA Compared to Placebo on Acute Menstrual Pain Levagen+, Microcrystalline cellulose - Menstrual Pain | Phase 4 | Completed | RDC Clinical Pty Ltd | 80 | 2023-05-19 | 2024-11-14 |
| Menstrual Complaints in Adolescents and Adults Menstruatie Educatie Kalender (Menstrution Education Calendar) application (MEK-app), Questionnaires - Dysmenorrhea, Heavy Menstrual Bleeding | Active not recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2000 | 2023-05-11 | 2025-04-10 | |
| An Investigation Into the Efficacy of a Botanical Supplement to Provide Period Relief Pamprin Botanicals, Pamprin Botanicals + Pamprin Menstrual Pain Relief - Menstrual Pain, Premenstrual Syndrome | Phase 1 | Completed | Focus Consumer Healthcare | 100 | 2023-02-08 | 2024-02-29 |
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Dysmenorrhea (34) · Menstruation Disturbances (5) · Pain (4) · Pelvic Pain (4) · Premenstrual Syndrome (4) · Anxiety Disorders (3) · Endometriosis (3) · Leiomyoma (3) · Adenomyosis (2) · Polycystic Ovary Syndrome (2) · Agnosia (1) · Depression (1) · Endocrine System Diseases (1) · Fatigue (1) · Menorrhagia (1)
Pathologic Processes (34) · Pathological Conditions, Signs and Symptoms (34) · Signs and Symptoms (34) · Neurologic Manifestations (33) · Pain (30) · Pelvic Pain (30) · Menstruation Disturbances (29) · Female Urogenital Diseases (7) · Female Urogenital Diseases and Pregnancy Complications (7) · Genital Diseases (7) · Genital Diseases, Female (7) · Urogenital Diseases (7) · Mental Disorders (5) · Neoplasms (4) · Uterine Diseases (4)
Exercise (2) · Aromatase (1) · Aromatase Inhibitors (1) · Control Groups (1) · Exergaming (1) · Gonadotropin-Releasing Hormone (1) · Ibuprofen (1) · Leuprolide (1) · Music Therapy (1) · Myofascial Release Therapy (1) · Naproxen (1) · Nutrition Assessment (1) · Proprioception (1) · Surveys and Questionnaires (1) · Telerehabilitation (1)
Halic University (2) · Zenchi, Inc. (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Ankara Yildirim Beyazıt University (1) · Azusa Pacific University (1) · Bulent Ecevit University (1) · Cairo University (1) · Centre for Endocrinology and Reproductive Medicine, Italy (1) · Centro Universitario La Salle (1) · Charite University, Berlin, Germany (1) · Cornell University (1) · Cynthia del Rocío Márquez Beltrán (1) · Focus Consumer Healthcare (1) · Hacettepe University (1) · Kevin Hellman (1)
United States (11) · Turkey (Türkiye) (7) · Spain (3) · Egypt (2) · Albania (1) · Australia (1) · Bulgaria (1) · Germany (1) · Indonesia (1) · Italy (1) · Netherlands (1) · Norway (1) · Pakistan (1) · Taiwan (1)
Susanne Mitschke (2) · Amanda Rao, PhD (1) · Beatriz Navarro Brazalez, PhD (1) · Claudia M Witt, MD (1) · Derrick Sueki, PT, PhD, DPT (1) · Doaa Osman, As professor (1) · Doaa Saeed, PhD (1) · Frank Tu, MD, MPH (1) · Hayam M Mahmoud, PhD (1) · Hossam Kamel, Professor (1)
PMID 19341553, PMID 20074018, PMID 22588748, PMID 24499425, PMID 29855308, PMID 32522750, PMID 33026291, PMID 37076044, PMID 37623203, PMID 38807793, PMID 41108303, PMID 42252834, PMID 42699717, PMID 42834980