18 completed, 3 unknown, 1 not yet recruiting, 1 terminated. 24 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 24 | Completed 18, Unknown 3, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
Follow Malaria, Vivax: new trials by email Literature Review of Malaria, Vivax trials Research Report on Malaria, Vivax
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tafenoquine Combinations for Improved Radical Cure Efficacy of Plasmodium Vivax Tafenoquine (TQ), Chloroquine (CQ), Dihydroartemisinin-piperaquine (DHA-PPQ) - Uncomplicated P. Vivax Mono-infection | Not applicable | Not yet recruiting | Walter Reed Army Institute of Research (WRAIR) | 300 | 2026-05-01 | 2026-04-16 |
| Efficacy of Chloroquine-Primaquine Treatment for Uncomplicated Plasmodium Vivax Malaria CQ-PQ - Malaria Vivax | Not applicable | Completed | Jimma University | 192 | 2024-12-01 | 2026-08-10 |
| Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia Revised case management package - Vivax Malaria, G6PD Deficiency | Not applicable | Completed | Menzies School of Health Research | 2999 | 2023-08-07 | 2026-01-15 |
| Short Course Primaquine for the Radical Cure of P. Vivax - Papua New Guinea Revised case management package - Vivax Malaria, G6PD Deficiency | Not applicable | Completed | Macfarlane Burnet Institute for Medical Research and Public Health Ltd | 794 | 2023-08-07 | 2026-09-02 |
| Radical CUREfor MAlaria Among Highly Mobile and Hard-to-reach Populations in the Guyanese Shield PART, Malakit, CROSS-SECTIONAL PRE- AND POST-INTERVENTION SURVEYS - Malaria, Vivax | Not applicable | Completed | Centre Hospitalier de Cayenne | 1991 | 2022-09-12 | 2025-07-24 |
| Performance Evaluation of Malaria Plus Rapid Diagnostic Tests (RDTs) for the Detection of Plasmodium Infections in Patients With Symptoms Suggestive of Malaria NxTekTM Malaria Pf Plus Rapid Diagnostic Test Device - Malaria | Not applicable | Completed | Abbott Rapid Dx | 1023 | 2022-05-24 | 2023-04-24 |
| Serological Screen and Treat Trial for Plasmodium Vivax Serological screen and treat - Malaria, Vivax | Not applicable | Unknown | Universitas Indonesia | 1133 | 2022-02-09 | 2023-03-07 |
| Targeting High Risk Populations With Enhanced Reactive Focal Mass Drug Administration in Thailand Case Management and Follow-up, Reactive focal mass drug administration (rfMDA) - Plasmodium Falciparum Malaria, Plasmodium Vivax Malaria | Not applicable | Completed | University of California, San Francisco | 14977 | 2020-11-01 | 2026-04-29 |
| Targeting High Risk Populations With Enhanced Reactive Case Detection in Southern Lao Peoples Democratic Republic Household Reactive Case Detection, RACD of cases' co-workers/co-travelers, Case Management and Follow-up - Plasmodium Falciparum Malaria, Plasmodium Vivax Malaria | Not applicable | Withdrawn | University of California, San Francisco | 2020-09-20 | 2026-04-29 | |
| Biomarkers of P. Vivax Relapse Primaquine - Malaria, Vivax Malaria | Not applicable | Unknown | Armed Forces Research Institute of Medical Sciences, Thailand | 100 | 2019-11-19 | 2020-01-14 |
| Efficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar Focal Mass Drug Administration with Primaquine - Malaria, Mass Drug Administration | Not applicable | Unknown | Pyae Linn Aung | 1208 | 2019-07-01 | 2024-04-30 |
| Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, Brazil Primaquine - P Vivax, Malaria, Vivax | Not applicable | Completed | Centers for Disease Control and Prevention | 257 | 2018-04-09 | 2021-08-09 |
| Study of Controlled Human Plasmodium Vivax Infection Plasmodium vivax infection, Collection of 250mL blood from each volunteer (N=2) - Malaria, Vivax | Not applicable | Completed | University of Oxford | 2 | 2018-03-03 | 2023-06-29 |
| Malaria in Early Life Study dihydroartemisinin-piperaquine - Plasmodium Falciparum Malaria, Plasmodium Vivax Malaria | Not applicable | Completed | Gadjah Mada University | 757 | 2014-07-21 | 2018-08-02 |
| IMPROV (Improving the Radical Cure of Vivax Malaria) Primaquine, Placebo - Uncomplicated Vivax Malaria | Not applicable | Completed | University of Oxford | 2388 | 2014-07-01 | 2019-09-17 |
| Malaria Prevention Cambodia DHA-piperaquine, placebo - Malaria | Not applicable | Terminated | Armed Forces Research Institute of Medical Sciences, Thailand | 231 | 2012-05-01 | 2016-07-12 |
| Chloroquine Population Pharmacokinetics in Pre and Post-partum Women Chloroquine - Vivax Malaria | Not applicable | Completed | University of Oxford | 49 | 2011-06-01 | 2019-01-08 |
| Malaria Active Epidemiology and Treatment Study Dihydroartemisinin piperaquine - Malaria | Not applicable | Completed | Armed Forces Research Institute of Medical Sciences, Thailand | 222 | 2010-09-01 | 2021-03-03 |
| Incidence of Vivax Along the Thai Burma Border Primaquine - Vivax Malaria | Not applicable | Completed | University of Oxford | 403 | 2010-02-01 | 2023-01-17 |
| Ethiopia Malaria Therapeutic Efficacy Study Chloroquine- P. vivax, Artemether-Lumefantrine: P. vivax, Artemether-lumefantrine: P. falciparum - Malaria | Not applicable | Completed | Centers for Disease Control and Prevention | 354 | 2009-10-01 | 2010-11-18 |
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Malaria, Falciparum (11) · Malaria (9) · Recurrence (4) · Glucosephosphate Dehydrogenase Deficiency (2)
Infections (24) · Mosquito-Borne Diseases (24) · Parasitic Diseases (24) · Protozoan Infections (24) · Vector Borne Diseases (24) · Malaria (15) · Disease Attributes (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Anemia (2) · Anemia, Hemolytic (2) · Anemia, Hemolytic, Congenital (2) · Carbohydrate Metabolism, Inborn Errors (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Genetic Diseases, Inborn (2)
Primaquine (6) · Chloroquine (4) · Case Management (2) · fanasil, pyrimethamine drug combination (2) · tafenoquine (2) · Amodiaquine (1) · Artemether, Lumefantrine Drug Combination (1) · Artesunate (1) · Pyrimethamine (1)
Menzies School of Health Research (4) · University of Oxford (4) · Armed Forces Research Institute of Medical Sciences, Thailand (3) · Centers for Disease Control and Prevention (2) · University of California, San Francisco (2) · Walter Reed Army Institute of Research (WRAIR) (2) · Abbott Rapid Dx (1) · Centre Hospitalier de Cayenne (1) · Gadjah Mada University (1) · Jimma University (1) · Macfarlane Burnet Institute for Medical Research and Public Health Ltd (1) · Pyae Linn Aung (1) · Universitas Indonesia (1)
Indonesia (7) · Thailand (5) · Ethiopia (4) · Brazil (2) · Cambodia (2) · Afghanistan (1) · Burma (1) · Laos (1) · Papua New Guinea (1) · Peru (1) · Suriname (1) · United Kingdom (1) · Vietnam (1)
Adam Bennett, MA, PhD (2) · Emiliana Tjitra (2) · Alan Magill, MD (1) · Alexandre Macedo de Oliveira, MD (1) · Angela M Minassian (1) · Brian Vesely, PhD (1) · Chanthap Lon, MD (1) · Cheewanan Lertpiriyasuwat, MD (1) · Dr. Lemu Golassa, PhD (1) · Emiliana Tjitre, PhD (1) · Francois Nosten, MD (1) · Inge Sutanto, MD, PhD (1) · Jeanne R Poespoprodjo, MD, MSc, PhD (1) · Jimee Hwang, MD (1)
PMID 28193647, PMID 40670924, PMID 15155976, PMID 15330070, PMID 17336652, PMID 19707564, PMID 21798054, PMID 23717423, PMID 25877962, PMID 26643116, PMID 26747132, PMID 34609964, PMID 35353962, PMID 35672703, PMID 37667204, PMID 37672548, PMID 38103896, PMID 40274531, PMID 40799786, PMID 40814099, PMID 41044665, PMID 42326839, PMID 42798354