3 completed, 2 recruiting, 2 withdrawn, 1 not yet recruiting. 9 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 3, Recruiting 2, Withdrawn 2, Not yet recruiting 1, Terminated 1 |
| Phase 1 | 1 | Withdrawn 1 |
Follow Lung Transplant: new trials by email Literature Review of Lung Transplant trials Research Report on Lung Transplant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Targeting Interferon Gamma With Emapalumab to Lung Transplant Recipients With Interferon Gamma-high Acute Lung Allograft Dysfunction Emapalumab, Placebo - Lung Transplant | Phase 2 | Not yet recruiting | University of California, San Francisco | 40 | 2026-11-02 | 2026-04-20 |
| Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients Belumosudil, Placebo for Belumosudil - Lung Transplant | Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 234 | 2025-03-12 | 2026-08-10 |
| Tocilizumab in Lung Transplantation Tocilizumab, Placebo for Tocilizumab - Lung Transplant | Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 100 | 2024-02-13 | 2026-10-08 |
| Utilization of Hepatitis B Virus NAT+ Donors for Hepatitis B Vaccinated Lung Transplant Candidates Hepatitis B Immune Globulin and entecavir, tenofovir disoproxil, or tenofovir alafenamide - Lung Transplant, Hepatitis B | Phase 2 | Withdrawn | University of Pennsylvania | 2022-09-06 | 2024-08-06 | |
| Letermovir for CMV Prevention After Lung Transplantation Letermovir, Valganciclovir - Lung Transplant, CMV | Phase 2 | Completed | Fernanda P Silveira, MD, MS | 15 | 2021-12-06 | 2026-04-09 |
| PRETELL: PREvention of TELomere-related Complications After Lung Transplant Danazol Pill, Placebo - Short Telomere Length, Lung Transplant | Phase 1 / Phase 2 | Withdrawn | Brigham and Women's Hospital | 2021-01-01 | 2023-02-15 | |
| Envarsus XR in Lung Transplant Extended-Release Tacrolimus, Immediate-Release Tacrolimus - Lung Transplant | Phase 2 | Completed | NYU Langone Health | 41 | 2020-10-23 | 2024-01-22 |
| B Cell Induction in Pediatric Lung Transplantation Rituximab (Rituxan®), Placebo - Lung Transplant | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 45 | 2015-01-22 | 2021-10-26 |
| Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide Inhaled Nitric Oxide - Pulmonary Hypertension, Lung Disease | Phase 2 | Terminated | Mallinckrodt | 7 | 2002-04-01 | 2016-09-09 |
Acute Lung Injury (1) · Anemia, Sickle Cell (1) · Hepatitis B (1) · Hypertension, Pulmonary (1) · Leukopenia (1) · Lung Diseases (1) · Organizing Pneumonia (1)
Hematologic Diseases (2) · Hemic and Lymphatic Diseases (2) · Respiratory Tract Diseases (2) · Anemia (1) · Anemia, Hemolytic (1) · Anemia, Hemolytic, Congenital (1) · Blood-Borne Infections (1) · Bronchial Diseases (1) · Bronchiolitis (1) · Bronchiolitis Obliterans (1) · Bronchitis (1) · Cardiovascular Diseases (1) · Communicable Diseases (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Cytopenia (1)
Danazol (1) · Emapalumab (1) · Endothelium-Dependent Relaxing Factors (1) · Rituximab (1) · Tacrolimus (1) · Tenofovir (1) · Valganciclovir (1) · belumosudil (1) · entecavir (1) · hepatitis B hyperimmune globulin (1) · letermovir (1) · tenofovir alafenamide (1) · tocilizumab (1)
National Institute of Allergy and Infectious Diseases (NIAID) (3) · Brigham and Women's Hospital (1) · Fernanda P Silveira, MD, MS (1) · Mallinckrodt (1) · NYU Langone Health (1) · University of California, San Francisco (1) · University of Pennsylvania (1)
United States (8) · Canada (1)
Andrew M Courtwright, MD, PhD (1) · Daniel Kreisel, M.D. (1) · Fernanda Silveira (1) · John Belperio, Dr. (1) · John Greenland, Dr. (1) · Joren Madsen, MD, D.Phil. (1) · Lara Danziger-Isakov, M.D., M.P.H. (1) · Luis Angel, MD (1) · Ramsey Hachem, MD (1) · Scott M. Palmer, M.D., M.H.S. (1) · Steven H Abman, MD (1) · Stuart Sweet, M.D., Ph.D. (1)