13 completed, 10 unknown, 8 recruiting, 8 terminated. 19 Phase 2, 11 Phase 1, 10 Not applicable, 2 Phase 3, 1 Early Phase 1.
Follow Lung Cancer Metastatic: new trials by email Literature Review of Lung Cancer Metastatic trials Research Report on Lung Cancer Metastatic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01) BL-M14D1 and Atezolizumab, Carboplatin+ Etoposide + Atezolizumab followed by Atezolizumab and Lurbinectedin - Small Cell Lung Cancer Extensive Stage, Small-cell Lung Cancer | Phase 3 | Recruiting | SystImmune Inc. | 550 | 2026-08-04 | 2026-10-15 |
| Phase 1B Trial of Intratumoral Cisplatin for Stage IV Lung Cancer cisplatin (cis-diamminedichloroplatinum(II) (CDDP)) - Lung Cancer Metastatic, Lung Cancer (NSCLC) | Phase 1 | Not yet recruiting | University of Vermont | 12 | 2026-07-01 | 2026-03-27 |
| Clinical Application Study of PET/CT for Differential Diagnosis of Non-small Cell Lung Cancer [68Ga]Ga-NOTA-T4, [68Ga]Ga-NOTA-RT4, [18F]F-RESCA-T4 - Lung Cancer, Lung Diseases | Not applicable | Recruiting | RenJi Hospital | 100 | 2024-12-23 | 2025-06-18 |
| Study to Investigate Luveltamab Tazevibulin in Adults With Advanced or Metastatic Non-small Cell Lung Cancer Luveltamab tazevibulin - Lung Cancer, Lung Cancer Metastatic | Phase 2 | Withdrawn | Sutro Biopharma, Inc. | 2024-08-21 | 2025-08-22 | |
| TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Lung Cancer Tumor Infiltrating Lymphocytes (TIL), Cyclophosphamide, Fludarabine - Lung Cancer, Lung Cancer Metastatic | Phase 1 / Phase 2 | Recruiting | Essen Biotech | 85 | 2024-08-20 | 2024-10-15 |
| SPSIPB vs SAPB for Thoracoscopic Surgery SPSIPB blcok, SAPB block, Postoperative analgesia management - Lung Diseases, Lung Cancer | Not applicable | Completed | Medipol University | 46 | 2024-08-10 | 2026-09-17 |
| A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs KB707, Pembrolizumab (KEYTRUDA®), Chemotherapy - Lung Cancer, Non-small Cell, Lung Cancer Metastatic | Phase 1 / Phase 2 | Recruiting | Krystal Biotech, Inc. | 250 | 2024-04-17 | 2025-10-24 |
| Primary Tumor Resection for M1a Stage Lung Cancer Lung Cancer Metastatic, Surgical Resection | Recruiting | Fudan University | 66 | 2024-04-01 | 2026-07-08 | |
| Novel Light Delivery Method for Performing Transbronchial Photodynamic Therapy for Peripheral Lung Cancer Transbronchial PDT peripheral lung tumor ablation - Lung Cancer, Lung Cancer Metastatic | Not applicable | Unknown | Taoyuan General Hospital | 3 | 2024-03-01 | 2024-02-16 |
| Testing Experimental Anti-cancer Drug SLC-391 With an Approved Immunotherapy Drug, Pembrolizumab, for Advanced Lung Cancers SLC-391, pembrolizumab - Lung Cancer, Nonsmall Cell, Lung Cancer Stage IV | Phase 1 / Phase 2 | Terminated | SignalChem Lifesciences Corporation | 36 | 2023-05-31 | 2025-12-18 |
| The Alterations of Metabolic Adipo-myokines and Body Composition in End Stage Lung Cancer Lung Cancer Metastatic | Unknown | Chang Gung Memorial Hospital | 600 | 2023-02-02 | 2023-09-29 | |
| Clinical and Molecular Findings in Patients With Cervical/Supraclavicular Metastasis From Non-small-cell Lung Cancer (NSCLC) Needle or forceps biopsy of cervical and/or supraclavicular lymph nodes, Needle, forceps or surgical biopsy of any lesion other than cervical and/or supraclavicular lymph nodes - Lung Cancer Metastatic | Completed | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 348 | 2023-01-01 | 2024-04-05 | |
| I3LUNG: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy Non Small Cell Lung Cancer, Lung Cancer Metastatic | Recruiting | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 2200 | 2022-10-01 | 2023-01-06 | |
| Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer [18F]-αvβ6-BP - Lung Cancer, Lung Cancer Metastatic | Phase 1 | Recruiting | University of California, Davis | 20 | 2022-09-13 | 2026-02-27 |
| A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain Stereotactic Radiosurgery, Cerebrospinal fluid collection - Lung Cancer, Lung Cancer Metastatic | Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 62 | 2022-06-10 | 2026-06-10 |
| Pembro+Chemo in Brain Mets Pembrolizumab, Nab paclitaxel, Paclitaxel - Lung Cancer, Lung Cancer Metastatic | Phase 2 | Terminated | John L. Villano, MD, PhD | 3 | 2022-05-19 | 2025-10-31 |
| DBT for Metastatic Lung Cancer Dialectical Behavioral Therapy Skills Training - Lung Cancer Metastatic | Not applicable | Completed | Duke University | 31 | 2022-05-18 | 2025-04-27 |
| A Randomized Pilot Study of Evolocumab Plus Nivolumab/Ipilimumab in Treatment-Naïve Patients With Metastatic NSCLC Nivolumab, Ipilimumab, Evolocumab - Lung Cancer Metastatic | Phase 2 | Terminated | Eziafa Oduah, MD, PhD, MPH | 19 | 2022-03-22 | 2026-05-05 |
| Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO Reduced dose intensity of IO - Lung Cancer Metastatic, Renal Cell Carcinoma | Phase 3 | Active not recruiting | UNICANCER | 646 | 2022-03-08 | 2026-07-17 |
| Stereotactic Body Radiotherapy for Lung Lesions With Markerless Tracking (MLT) on the VERO® SBRT System Standard radiotherapy treatment - Lung Cancer, Stereotactic Body Radiotherapy | Withdrawn | Universitair Ziekenhuis Brussel | 2022-01-01 | 2024-12-09 |
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Lung Neoplasms (27) · Carcinoma, Non-Small-Cell Lung (15) · Neoplasms (5) · Brain Neoplasms (4) · Small Cell Lung Carcinoma (4) · Adenocarcinoma of Lung (3) · Lung Diseases (3) · Neoplasm Metastasis (2) · Carcinoma, Basal Cell (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Merkel Cell (1) · Carcinoma, Renal Cell (1) · Carcinoma, Small Cell (1) · Carcinoma, Transitional Cell (1) · Colorectal Cancer, Hereditary Nonpolyposis, Type 8 (1)
Neoplasms by Site (35) · Neoplasms (33) · Respiratory Tract Diseases (32) · Respiratory Tract Neoplasms (32) · Thoracic Neoplasms (31) · Lung Diseases (29) · Bronchial Neoplasms (17) · Carcinoma, Bronchogenic (17) · Neoplasms by Histologic Type (6) · Carcinoma (5) · Lung Neoplasms (5) · Neoplasms, Glandular and Epithelial (5) · Adenocarcinoma (4) · Brain Diseases (4) · Central Nervous System Diseases (4)
pembrolizumab (5) · Cisplatin (3) · Carboplatin (2) · Docetaxel (2) · Nivolumab (2) · Pemetrexed (2) · osimertinib (2) · trametinib (2) · Adjuvants, Immunologic (1) · Cyclophosphamide (1) · Dihematoporphyrin Ether (1) · Drug Therapy (1) · EC regimen (1) · Erlotinib Hydrochloride (1) · Etoposide (1)
Asan Medical Center (3) · Memorial Sloan Kettering Cancer Center (3) · Sichuan Cancer Hospital and Research Institute (2) · University of Vermont (2) · BerGenBio ASA (1) · Broncus Medical Inc (1) · Canadian Cancer Trials Group (1) · Candiolo Cancer Institute - IRCCS (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Chang Gung Memorial Hospital (1) · Collin Blakely (1) · Concordia Laboratories Inc. (1) · Duke University (1) · Essen Biotech (1) · Eziafa Oduah, MD, PhD, MPH (1)
United States (20) · China (8) · Canada (5) · France (4) · Italy (3) · South Korea (3) · Spain (3) · Taiwan (3) · Australia (2) · Greece (2) · United Kingdom (2) · Belgium (1) · Bulgaria (1) · Czechia (1) · Georgia (1)
Alfredo Quinones Hinojosa, MB (1) · Anhui Shi, MD. (1) · Bertrand Routy, MD PhD (1) · C. Matthew Kinsey, MD, MPH (1) · Chiu-kuei Nien (1) · Christine Collen, MD (1) · Colleen Spees, PhD, MEd, RD, LD, FAND (1) · Collin Blakely, MD, PhD (1) · David Chien, MD (1) · Erin O'Neil (1) · FangFang Zhang, MD, PhD (1) · Helen Yu, MD (1) · Helena Yu, MD (1) · Houda Bahig, MD PhD (1)
PMID 24563870, PMID 26095785, PMID 34800700, PMID 35492873, PMID 36166003, PMID 37131154, PMID 37286305, PMID 41392376, PMID 41471387, PMID 42032732
2016 (1)