83 completed, 39 unknown, 26 recruiting, 15 not yet recruiting. 40 Not applicable, 24 Phase 2, 14 Phase 1, 12 Phase 3, 10 Phase 4.
Follow Liver Fibrosis: new trials by email Literature Review of Liver Fibrosis trials Research Report on Liver Fibrosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Different Treatment Frequencies for Hepatic Fibrosis Due to Schistosomiasis Praziquantel 40 mg/kg per dose given once annually, Praziquantel 40 mg/kg given three times per year - Schistosomiasis, Schistosoma Mansoni | Phase 2 / Phase 3 | Not yet recruiting | Rhode Island Hospital | 600 | 2026-11-01 | 2026-08-12 |
| Endohepatology-Based Reclassification of Treatment Indication in High-Risk MASLD Non-invasive MASLD and portal hypertension assessment, Single-session endohepatology assessment - Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis | Recruiting | University Hospital Muenster | 500 | 2026-10-05 | 2026-10-20 | |
| The Correlation Between hs CRP TG Triglycerides Glucose Index in NAFLD and Liver Fibrosis • Fasting triglycerides (TG) • Fasting plasma glucose • High-sensitivity C-reactive protein (hs-CRP) • Liver enzymes (ALT, AST, GGT) • Platelet count • HbA1c • Lipid profile (total cholesterol, HDL-C, - Liver Fibrosis | Not yet recruiting | Assiut University | 96 | 2026-10-02 | 2026-04-07 | |
| Wearable Patch Ultrasound Probe for Diagnosis of Liver Stiffness Wearable Patch-Type Ultrasound Probe, Transient Elastography (FibroScan) - Liver Fibrosis, Liver Cirrhosis | Not yet recruiting | Second Affiliated Hospital of Xi'an Jiaotong University | 150 | 2026-10-01 | 2026-07-21 | |
| Impact of Overt and Subclinical Hypothyroidism on Liver Fibrosis in Patients With MASLD Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-Alcoholic Fatty Liver Disease | Not yet recruiting | Assiut University | 120 | 2026-10-01 | 2026-09-18 | |
| Nutritional Indices and Inflammatory Markers in MASLD Liver Fibrosis, Malnutrition | Not yet recruiting | Assiut University | 180 | 2026-09-20 | 2026-09-22 | |
| Umbilical Cord Mesenchymal Stem Cell Therapy for Biliary Atresia Umbilical Cord-Mesenchymal Stem Cells (UC-MSC), Kasai Portoenterostomy - Biliary Atresia, Kasai Operation | Phase 1 | Recruiting | Dr Cipto Mangunkusumo General Hospital | 40 | 2026-09-01 | 2026-09-09 |
| Isocaloric Navy-Bean Substitution in Adults With MASLD Dietary Supplement/Behavioral: Navy Bean-Rich Diet, Habitual Diet (Control) - Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), Liver Fibrosis | Not applicable | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 40 | 2026-09-01 | 2026-08-12 |
| Sonazoid CEUS for Early HCC Surveillance Sonazoid CEUS - Liver Cirrhosis, Liver Fibrosis | Not applicable | Not yet recruiting | Tianjin Third Central Hospital | 556 | 2026-05-30 | 2026-05-15 |
| Patients With Primary Biliary Cholangitis(PBC) Primary Biliary Cholangitis, Liver Fibrosis | Active not recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 30 | 2026-05-18 | 2026-06-05 | |
| Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis AZD2389, Placebo - Liver Fibrosis, Hepatic Cirrhosis | Phase 2 | Recruiting | AstraZeneca | 104 | 2026-05-07 | 2026-10-19 |
| Correlation Of EUS-SWQ And Liver Fibrosis Pathology In Chronic Liver Disease Chronic Liver Disease (CLD), Liver Fibrosis | Recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 65 | 2026-05-01 | 2026-05-15 | |
| Samsung S-Viscosity vs Canon Dispersion Slope in Steatotic Liver Disease (SAVID-SLD) Samsung Medison HERA W12 (R30) with S-Shearwave platform, Canon Aplio i800 with Dispersion Slope Imaging - Metabolic Dysfunction-Associated Steatotic Liver Disease, Fatty Liver | Active not recruiting | Seoul National University Hospital | 95 | 2026-04-24 | 2026-10-13 | |
| Prevalence and Risk Factors of Metabolic-Associated Hepatic Steatosis in Individuals Living With Type 1 Diabetes Adiposity and BMI Classification - Type 1 Diabetes, Liver Steatoses | Not yet recruiting | Institut de Recherches Cliniques de Montreal | 100 | 2026-04-01 | 2026-03-23 | |
| Study of Hydroxynidone Capsules in Patients With Hepatic Impairment and Matched Healthy Controls Hydronidone capsules - Liver Fibrosis | Phase 1 | Completed | Beijing Continent Pharmaceutical Co, Ltd. | 30 | 2026-03-25 | 2026-08-13 |
| Interventional AI-Human Collaboration for Steatotic Liver Disease Screening AI-human collaboration for SLD screening - Steatotic Liver Disease, Liver Fibrosis Progression in Chronic Liver Disease | Not applicable | Enrolling by invitation | Shengjing Hospital | 7969 | 2026-02-24 | 2026-05-29 |
| A Phase IIIc Clinical Study to Evaluate the Long-term Treatment of Hydronidone Capsules for Liver Fibrosis in Patients With Chronic Hepatitis B. Hydronidone (270mg), Hydronidone (Placebo Group) - Liver Fibrosis, Liver Fibrosis in Chronic Hepatitis B | Phase 3 | Not yet recruiting | Beijing Continent Pharmaceutical Co, Ltd. | 1208 | 2026-01-30 | 2026-02-17 |
| City-Hospital Collaboration for Early Detection of Liver Fibrosis in Primary Care: A Secondary Prevention Project in the Grenoble Health Area Non-interventional study (RIPH category 3) - Liver Fibrosis | Recruiting | University Hospital, Grenoble | 150 | 2026-01-14 | 2026-03-02 | |
| The Phase Ⅰd Clinical Trial of Hydronidone Capsules Hydronidone capsules, Placebo capsules - Liver Fibrosis | Phase 1 | Completed | Beijing Continent Pharmaceutical Co, Ltd. | 138 | 2025-12-24 | 2026-09-21 |
| Is There a Relationship Between Uric Acid Level and Liver Fibrosis in Obese Patients *Lab Methods:* 1- Serum Uric Acid levels 2-Liver Function Tests 3- Lipid Profile . 4- Haemoglobin A1c level . 5- Serum glucose level ., *Imaging Studies:* 1- Ultrasound 2 - FibroScan, Instruments:* 1- *Automated Analyzers*: Used for blood tests, such as serum uric acid and liver function tests. - Hyperuricemia, NAFLD (Nonalcoholic Fatty Liver Disease) | Not yet recruiting | Assiut University | 111 | 2025-10-01 | 2025-09-15 |
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Liver Cirrhosis (179) · Non-alcoholic Fatty Liver Disease (34) · Fibrosis (26) · Fatty Liver (22) · Liver Diseases (14) · Hepatitis B (13) · Hepatitis C (11) · Obesity (11) · Hepatitis B, Chronic (8) · Hypertension, Portal (7) · Carcinoma, Hepatocellular (6) · Hepatitis (6) · Diabetes Mellitus, Type 2 (5) · Hepatitis C, Chronic (4) · Liver Diseases, Alcoholic (4)
Pathologic Processes (179) · Pathological Conditions, Signs and Symptoms (179) · Digestive System Diseases (178) · Liver Diseases (165) · Fibrosis (153) · Infections (32) · Blood-Borne Infections (30) · Communicable Diseases (30) · Virus Diseases (30) · Hepatitis (29) · Hepatitis, Viral, Human (29) · Fatty Liver (24) · Nutritional and Metabolic Diseases (22) · DNA Virus Infections (19) · Hepadnaviridae Infections (19)
hydronidone (5) · Hematologic Tests (4) · Tenofovir (4) · peginterferon alfa-2a (4) · peginterferon alfa-2b (4) · Magnetic Resonance Spectroscopy (3) · Pegbelfermin (3) · 5-methyl-1-(4-hydroxylphenyl)-2-(1H)-pyridone (2) · Blood Specimen Collection (2) · Diet Therapy (2) · Dietary Supplements (2) · Docosahexaenoic Acids (2) · Portoenterostomy, Hepatic (2) · Positron-Emission Tomography (2) · Praziquantel (2)
Assiut University (5) · Beijing Continent Pharmaceutical Co, Ltd. (5) · Beijing Friendship Hospital (4) · Bristol-Myers Squibb (4) · Chinese University of Hong Kong (4) · Third Affiliated Hospital, Sun Yat-Sen University (4) · AstraZeneca (3) · Echosens (3) · Fifth Affiliated Hospital, Sun Yat-Sen University (3) · University Hospital, Angers (3) · Assistance Publique - Hôpitaux de Paris (2) · Association HGE CHU Bordeaux Sud (2) · Bambino Gesù Hospital and Research Institute (2) · China Medical University Hospital (2) · Conatus Pharmaceuticals Inc. (2)
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Xi Liu, PhD (3) · Eric Bellissant, MD, PhD (2) · Guiqiang Wang (2) · Juliette Foucher, MD (2) · Liang Peng, Doctor (2) · Sheng-Hung Chen, MD (2) · Valerio Nobili, MD (2) · Adam Vasura, MD (1) · Adrian P Regensburger (1) · Alexander Schnell (1) · Ali Aminian, MD (1)
PMID 33657443, PMID 37396307, PMID 15685546, PMID 16628644, PMID 17133503, PMID 18030211, PMID 18666139, PMID 19628656, PMID 19670411, PMID 20828377, PMID 21233083, PMID 21349784, PMID 21376047, PMID 21436087, PMID 21574172, PMID 21751289, PMID 21839040, PMID 21940902, PMID 22752522, PMID 22798311, PMID 22821944, PMID 23159770, PMID 23220074, PMID 24074360, PMID 24243654, PMID 24519328, PMID 24637083, PMID 24759906, PMID 25149296, PMID 25381721, PMID 25384923, PMID 26010456, PMID 26096227, PMID 26497954, PMID 27034453, PMID 27232579, PMID 27239119, PMID 27714681, PMID 27981751, PMID 28158504, PMID 28480218, PMID 28962551, PMID 29119002, PMID 29551711, PMID 29730602, PMID 30138687, PMID 31166567, PMID 31559605, PMID 31725459, PMID 32027858
2005 (1), I01CX002436 (1), R01AI184979 (1), R01DK106957 (1), U01DK062436 (1), U01DK062445 (1), U01DK062452 (1), U01DK062453 (1), U01DK062456 (1), U01DK062466 (1), U01DK062470 (1), U01DK062481 (1), U01DK062497 (1), U01DK062500 (1), U01DK062503 (1)