24 completed. 24 Phase 2, 6 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 24 | Completed 24 |
| Phase 1 | 6 | Completed 6 |
| Phase 3 | 2 | Completed 2 |
Follow Kidney Calculi: new trials by email Literature Review of Kidney Calculi trials Research Report on Kidney Calculi
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2a Study of LLX-424 in Patients With a History of Kidney Stones LLX-424 - Kidney Stones | Phase 2 | Completed | Lilac Therapeutics, Inc. | 51 | 2025-03-23 | 2025-10-29 |
| Erector Spinae Plane Block for Uncomplicated Renal Colic Erector Spinae Plane Block (ESPB), Ropivacaine - Renal Colic, Kidney Stone | Phase 2 | Completed | University of Michigan | 5 | 2023-02-08 | 2025-10-30 |
| Silodosin in Management of Lower Ureteral Stones Silodosin - Stone, Kidney | Phase 1 / Phase 2 | Completed | Syrian Private University | 100 | 2022-10-20 | 2024-04-24 |
| Impact of the SGLT2 Inhibitor Empagliflozin on Urinary Supersaturations in Kidney Stone Formers Empagliflozin 25 MG, Placebo - Kidney Stone | Phase 2 | Completed | Insel Gruppe AG, University Hospital Bern | 50 | 2021-08-25 | 2023-05-12 |
| Perioperative Pregabalin in Ureteroscopy Pregabalin 300mg, Placebo oral tablet - Kidney Stone, Pain, Postoperative | Phase 2 / Phase 3 | Completed | University of Missouri-Columbia | 118 | 2020-06-01 | 2025-11-12 |
| Pramipexole and Morphine for Renal Colic Pramipexole, Morphine, Placebo oral tablet - Renal Colic | Phase 1 / Phase 2 | Completed | East Carolina University | 19 | 2019-10-28 | 2023-03-08 |
| Efficacy and Safety of Renalof® in the Removal of Calculi Smaller Than 10 mm Located in the Reno-Ureteral Tract Renalof, Placebo - Renal Injury, Kidney Injury | Phase 2 | Completed | Catalysis SL | 155 | 2019-08-01 | 2021-01-06 |
| Study of ALLN-177 in Patients Aged 12 Years or Older With Enteric or Primary Hyperoxaluria and Hyperoxalemia ALLN-177 - Enteric Hyperoxaluria, Primary Hyperoxaluria | Phase 2 | Completed | Allena Pharmaceuticals | 15 | 2018-07-17 | 2020-12-30 |
| Prospective Randomized Controlled Trial for Pain Relief After Office Ureteral Stent Removal Ketorolac, normal saline - Pain, Urinary Stone | Phase 2 | Completed | University of Texas Southwestern Medical Center | 125 | 2018-06-28 | 2024-01-10 |
| Toradol to Reduce Ureteroscopic Symptoms Trial Toradol - Urinary Lithiasis, Kidney Diseases | Phase 2 | Completed | Yale University | 94 | 2017-08-01 | 2021-11-02 |
| Lipoic Acid Supplement for Cystine Stone Alpha lipoic acid, Placebo - Cystinuria | Phase 2 | Completed | Thomas Chi, MD | 50 | 2017-06-19 | 2026-04-15 |
| Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days ALLN-177, Placebo - Secondary Hyperoxaluria, Nephrolithiasis | Phase 2 | Completed | Allena Pharmaceuticals | 66 | 2015-09-01 | 2017-01-19 |
| Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Hyperoxaluria and Kidney Stones ALLN-177 low dose, ALLN-177 mid dose, ALLN-177 high dose - Secondary Hyperoxaluria, Nephrolithiasis | Phase 2 | Completed | Allena Pharmaceuticals | 32 | 2015-07-01 | 2018-01-11 |
| Comparing Pneumatic Versus Ultra-sonic Percutaneous Nephrolithotomy in Large Kidney Stones Pneumatic percutaneous nephrolithotomy, Ultra-sonic percutaneous nephrolithotomy - Kidney Stone | Phase 2 | Completed | Isfahan University of Medical Sciences | 180 | 2014-12-01 | 2016-04-26 |
| Evaluating ALLN-177 for Reducing Urinary Oxalate Excretion in Calcium Oxalate Kidney Stone Formers With Hyperoxaluria ALLN-177 - Hyperoxaluria, Nephrolithiasis | Phase 2 | Completed | Allena Pharmaceuticals | 16 | 2014-09-01 | 2019-06-05 |
| Treatment for Calcium Phosphate Kidney Stone Disease Placebo, Citric Acid, Potassium Citrate - Calcium Phosphate Kidney Stones | Phase 2 | Completed | University of Texas Southwestern Medical Center | 13 | 2012-07-01 | 2024-04-04 |
| Use of Lapis Judaicus to Dissolve Kidney Stones Lapis Judaicus, Placebo - Kidney Calculi | Phase 1 / Phase 2 | Completed | Shiraz University of Medical Sciences | 60 | 2011-01-01 | 2013-12-02 |
| Study of Silodosin to Facilitate Passage of Urinary Stones silodosin, placebo - Ureteral Calculi, Kidney Stones | Phase 2 | Completed | Watson Pharmaceuticals | 239 | 2010-06-01 | 2014-08-11 |
| Febuxostat Versus Allopurinol or Placebo in Patients With Hyperuricosuria and Calcium Oxalate Stones Febuxostat, Allopurinol, Placebo - Hyperuricosuria, Kidney Stones | Phase 2 | Completed | Takeda | 99 | 2010-02-01 | 2013-02-15 |
| Pharmacokinetic, Safety and Efficacy Study of OMS201 in Subjects Undergoing Retrograde Ureteroscopic Removal of Upper Urinary Tract Stones OMS201, Vehicle - Urinary Calculi, Urinary Stones | Phase 1 / Phase 2 | Completed | Omeros Corporation | 18 | 2009-03-01 | 2012-10-12 |
Showing 20 of 24. Sign in to see all of them.
Nephrolithiasis (7) · Kidney Diseases (5) · Urolithiasis (5) · Hyperoxaluria (4) · Renal Colic (3) · Urologic Diseases (3) · Calculi (2) · Cystinuria (2) · Nephrolithiasis, Calcium Oxalate (2) · Pain, Postoperative (2) · Ureteral Calculi (2) · Ureteral Obstruction (2) · Urinary Calculi (2) · Agnosia (1)
Female Urogenital Diseases (24) · Female Urogenital Diseases and Pregnancy Complications (24) · Male Urogenital Diseases (24) · Pathological Conditions, Anatomical (24) · Pathological Conditions, Signs and Symptoms (24) · Urogenital Diseases (24) · Calculi (22) · Urinary Calculi (22) · Urologic Diseases (21) · Kidney Diseases (19) · Urolithiasis (19) · Nephrolithiasis (17) · Signs and Symptoms (7) · Neurologic Manifestations (6) · Pain (5)
oxalate decarboxylase (4) · reloxaliase (4) · Ketorolac Tromethamine (2) · silodosin (2) · Allopurinol (1) · Citric Acid (1) · Febuxostat (1) · Isoproterenol (1) · Ketorolac (1) · Morphine (1) · Potassium Citrate (1) · Pramipexole (1) · Pregabalin (1) · Ropivacaine (1) · Saline Solution (1)
Allena Pharmaceuticals (4) · Mayo Clinic (2) · University of Texas Southwestern Medical Center (2) · Catalysis SL (1) · East Carolina University (1) · Fredericia Hosptial (1) · Insel Gruppe AG, University Hospital Bern (1) · Isfahan University of Medical Sciences (1) · Lilac Therapeutics, Inc. (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Omeros Corporation (1) · Shiraz University of Medical Sciences (1) · Syrian Private University (1) · Takeda (1) · Thomas Chi, MD (1)
United States (17) · Canada (1) · Denmark (1) · Germany (1) · Iran (1) · Nicaragua (1) · Switzerland (1) · Syria (1) · United Kingdom (1)
Annamaria Kausz, MD MS (2) · Chris Fung (1) · Daniel Fuster, MD (1) · David Clark, MD (1) · Jamshid Roozbeh, MD (1) · John C Lieske, MD (1) · John D Denstedt, MD, FRCSC (1) · Katie Murray, DO (1) · Kori Brewer, PhD (1) · Lee Brettman, MD, FACP (1) · Margaret Pearle, MD.PhD (1) · Naim M Maalouf, MD (1) · Nasser Simforoosh, Prof (1) · Palle JS Osther, PhD, MD (1) · Scott Olsen, MPH (1)
PMID 20736987, PMID 21161651, PMID 21419606, PMID 23929928, PMID 30783888, PMID 34569278, PMID 35288397, PMID 39411383, PMID 39747681
P50DK083007 (2), 2017 (1), P20DK100863 (1), R21AT002534 (1), R21DK097476 (1), UL1RR024150 (1)