11 completed, 1 terminated, 1 unknown. 5 Not applicable, 3 Phase 4, 2 Phase 3, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 5 |
| Phase 4 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 2 | Completed 2 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Kerato Conjunctivitis Sicca: new trials by email Literature Review of Kerato Conjunctivitis Sicca trials Research Report on Kerato Conjunctivitis Sicca
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Evaluating the Safety of the Nasal Pump Tyrvaya Nasal Pump - Dry Eye, Kerato Conjunctivitis Sicca | Phase 4 | Terminated | Oyster Point Pharma, Inc. | 5 | 2024-02-21 | 2025-05-02 |
| Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers Miebo - Dry Eye, Dry Eye, Evaporative | Phase 4 | Completed | Gordon Schanzlin New Vision | 49 | 2023-09-21 | 2024-04-09 |
| Efficacy and Safety Evaluation of Tavilermide Ophthalmic Solution for the Treatment of Dry Eye 5% Tavilermide ophthalmic solution, Vehicle ophthalmic solution - Dry Eye Syndromes, Dry Eye Disease | Phase 3 | Completed | Mimetogen Pharmaceuticals USA, Inc. | 642 | 2023-06-28 | 2024-06-10 |
| PMCF Study to Evaluate Performance and Safety of "HPMC-based Eyedrops" Used to Relieve Dry Eye Symptoms Hydroxypropyl methylcellulose eye drops - Dry Eye, Dry Eye Disease | Not applicable | Completed | C.O.C. Farmaceutici S.r.l. | 80 | 2022-09-06 | 2023-04-24 |
| PMCF Study to Evaluate Performance and Safety of "Distilled Waters-based Eyedrops" Used to Relieve Dry Eye Symptoms Distilled waters based eye drops - Dry Eye, Dry Eye Disease | Not applicable | Completed | C.O.C. Farmaceutici S.r.l. | 60 | 2022-08-02 | 2023-04-24 |
| PMCF Study to Evaluate Performance and Safety of "Hyaluronic Acid (HA)-Based Eyedrops" Used to Relieve Dry Eye Symptoms Hyaluronic acid eye drops - Dry Eye, Dry Eye Disease | Not applicable | Completed | C.O.C. Farmaceutici S.r.l. | 160 | 2022-06-24 | 2024-03-27 |
| PMCF Study to Evaluate Performance and Safety of "CLHA-based Eyedrops" Used to Improve Lacrimal Abnormalities Cross-linked hyaluronic acid eye drops - Dry Eye Disease, Dry Eye | Not applicable | Completed | C.O.C. Farmaceutici S.r.l. | 80 | 2022-06-10 | 2024-03-27 |
| PMCF Study to Evaluate Performance and Safety of "Ocular Drops Based Upon Carmellose" Used to Relieve Dry Eye Symptoms Carmellose eye drops - Dry Eye, Dry Eye Disease | Not applicable | Completed | C.O.C. Farmaceutici S.r.l. | 40 | 2022-03-24 | 2023-05-06 |
| Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease Pilocarpine Ophthalmic Topical Cream, Dose 1, Pilocarpine Ophthalmic Topical Cream, Dose 2, Pilocarpine Ophthalmic Topical Cream, Dose 3 - Dry Eye Disease, Kerato Conjunctivitis Sicca | Phase 2 | Completed | Glaukos Corporation | 226 | 2022-01-03 | 2023-07-12 |
| Tolerability Comparison of Flarex to Lotemax SM Fluorometholone Acetate Ophthalmic Suspension 0.1%, Loteprednol Etabonate Ophthalmic Gel 0.38% - Ocular Inflammation, Keratoconjunctivitis | Phase 4 | Completed | Harrow Inc | 40 | 2021-05-01 | 2026-09-22 |
| Treatment With Allogeneic Adipose-derived Mesenchymal Stem Cells in Patients With Aqueous Deficient Dry Eye Disease Adipose tissue-derived mesenchymal stem cells - Dry Eye, Kerato Conjunctivitis Sicca | Early Phase 1 | Completed | Copenhagen University Hospital, Rigshospitalet | 7 | 2019-10-16 | 2023-11-18 |
| DRy Eye Outcome and Prescription Study Artificial tears (classified by MHRA as a medical device) - Dry Eye, Dry Eye Syndrome | Unknown | Guy's and St Thomas' NHS Foundation Trust | 635 | 2018-08-23 | 2018-08-31 | |
| Safety and Efficacy of KPI-121 in Subjects With DED KPI-121 Ophthalmic Suspension, Vehicle - Kerato Conjunctivitis Sicca | Phase 3 | Completed | Kala Pharmaceuticals, Inc. | 901 | 2018-07-10 | 2021-04-02 |
Dry Eye Syndromes (13) · Eye Diseases (2) · Keratoconjunctivitis (2) · Blepharitis (1) · Corneal Diseases (1) · Eye Pain (1) · Meibomian Gland Dysfunction (1) · Postoperative Complications (1) · Xerophthalmia (1)
Lacrimal Apparatus Diseases (13) · Eye Diseases (11) · Conjunctival Diseases (3) · Conjunctivitis (2) · Keratitis (2) · Pathological Conditions, Signs and Symptoms (2) · Corneal Diseases (1) · Eye Manifestations (1) · Eyelid Diseases (1) · Neurologic Manifestations (1) · Pain (1) · Pathologic Processes (1) · Signs and Symptoms (1)
Fluorometholone (1) · perfluorohexyl-octan (1)
C.O.C. Farmaceutici S.r.l. (5) · Copenhagen University Hospital, Rigshospitalet (1) · Glaukos Corporation (1) · Gordon Schanzlin New Vision (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Harrow Inc (1) · Kala Pharmaceuticals, Inc. (1) · Mimetogen Pharmaceuticals USA, Inc. (1) · Oyster Point Pharma, Inc. (1)
United States (6) · Italy (5) · Denmark (1) · United Kingdom (1)
Joshua Davidson, OD, FAAO (1) · Steffen Heegaard, MD, DMSc (1)