6 completed, 3 recruiting, 1 enrolling by invitation, 1 not yet recruiting. 3 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 1 | 1 | Not yet recruiting 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow Joint Hypermobility: new trials by email Literature Review of Joint Hypermobility trials Research Report on Joint Hypermobility
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Regenerative Medicine for Joint Hypermobility and Instability Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational) - Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS) | Phase 1 / Phase 2 | Not yet recruiting | Manhattan Pain Medicine, PLLC | 100 | 2027-01-15 | 2026-10-06 |
| Characteristics of the Functional State of the Musculoskeletal System, Body Awareness, and Quality of Life in Individuals With Joint Hypermobility, Their Associations, and Guidelines for Intervention. No intervention - Joint Hypermobility | Enrolling by invitation | Lithuanian University of Health Sciences | 511 | 2026-02-01 | 2026-03-17 | |
| Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema Lipedema, Hypermobility Syndrome (Disorder) | Recruiting | Marmara University | 32 | 2026-01-01 | 2026-01-02 | |
| Hypermobility, Foot Posture, and Scoliosis Severity Assessment - Joint Hypermobility, Adolescent Idiopathic Scoliosis | Completed | Istinye University | 22 | 2025-12-15 | 2026-06-26 | |
| Prenatal Hormonal Markers and Sleep Characteristics in Young Adults With Joint Hypermobility The Beighton Scoring system, 2D:4D Digit Ratio - Joint Hypermobility, Healty Controls | Completed | Nigde Omer Halisdemir University | 180 | 2025-08-20 | 2025-12-24 | |
| The Effect of Lower Extremity Rotational Profile on Postural Control, Muscle Strength, Functional Capacity and Lower Extremity Function in Children With Generalized Joint Hypermobility Rotational Profile- Hip Internal and External Rotation Measurement, Rotational Profile- Craig's Test Measurement, Rotational Profile- Foot/Thigh Angle Measurement - Joint Hypermobility, Femoral Anteversion | Completed | Bezmialem Vakif University | 48 | 2025-07-01 | 2025-07-15 | |
| Fitness Integrative Training for Pediatric Rheumatology Disorders FIT Teens - Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus of Childhood | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 10 | 2024-09-24 | 2025-08-28 |
| Muscle Strength and Balance in Individuals With Joint Hypermobility Static balance assessment, Dynamic balance assessment:, Isokinetic strength evaluation: - Joint Hypermobility, Balance | Completed | Gazi University | 32 | 2024-01-15 | 2024-03-15 | |
| Functional Instability in Patients Suffering From Collagen Disease and Joint Hypermobility Clinical tests and balance evaluation using the Delos Proprioceptive System - Hypermobility Syndrome, Danlos Disease, Ehlers | Recruiting | Istituto Ortopedico Rizzoli | 30 | 2020-10-01 | 2025-07-20 | |
| The Clinical Outcomes of the Modified Broström vs Anatomic Reconstruction Operation in CLAI and GJL Modified Broström operation and anatomic reconstruction operation - Ankle Sprains, Instability, Joint | Recruiting | Peking University Third Hospital | 100 | 2020-01-01 | 2025-04-11 | |
| Gait Retraining in Patients With Joint Hypermobility Syndrome/Hypermobile Ehlers Danlos Syndrome Gait retraining program - Joint Hypermobility, Ehlers-Danlos Syndrome | Not applicable | Unknown | University of South Florida | 12 | 2018-10-01 | 2018-07-02 |
| The Clinical Outcomes of the Arthroscopic and Open Modified Broström Operation in CLAI and GJL Open or arthroscopic Modified Broström operation - Ankle Sprains, Instability, Joint | Not applicable | Completed | Peking University Third Hospital | 74 | 2018-01-08 | 2022-06-27 |
Joint Instability (12) · Ehlers-Danlos Syndrome (3) · Ankle Injuries (2) · Arthritis, Juvenile (1) · Collagen Diseases (1) · Dermatomyositis (1) · Ehlers-Danlos syndrome type 3 (1) · Flatfoot (1) · Joint Dislocations (1) · Lipedema (1) · Musculoskeletal Pain (1) · Reinjuries (1) · Sprains and Strains (1)
Joint Diseases (12) · Musculoskeletal Diseases (12) · Connective Tissue Diseases (5) · Skin and Connective Tissue Diseases (5) · Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Skin Diseases (4) · Cardiovascular Diseases (3) · Genetic Diseases, Inborn (3) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Hemorrhagic Disorders (3) · Hemostatic Disorders (3) · Skin Abnormalities (3) · Skin Diseases, Genetic (3)
Glucose (1) · Prolotherapy (1) · Restraint, Physical (1)
Peking University Third Hospital (2) · Bezmialem Vakif University (1) · Children's Hospital Medical Center, Cincinnati (1) · Gazi University (1) · Istinye University (1) · Istituto Ortopedico Rizzoli (1) · Lithuanian University of Health Sciences (1) · Manhattan Pain Medicine, PLLC (1) · Marmara University (1) · Nigde Omer Halisdemir University (1) · University of South Florida (1)
Turkey (Türkiye) (5) · China (2) · Italy (1) · Lithuania (1) · United States (1)
Dong Jiang, MD (2) · Jason Siefferman, MD (1) · Mariia Safroshkina, MD (1) · Susmita Kashikar-Zuck, PhD (1)
PMID 12612280, PMID 20850761, PMID 16182938, PMID 21777989, PMID 21833947, PMID 27480980, PMID 27496909, PMID 27524711, PMID 30893238, PMID 37162539, PMID 39317996, PMID 41693451