3 completed, 1 enrolling by invitation. 4 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Enrolling by invitation 1 |
| Phase 2 | 2 | Completed 1, Enrolling by invitation 1 |
Follow Iris Diseases: new trials by email Literature Review of Iris Diseases trials Research Report on Iris Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Topical Insulin for Glaucoma (TING2) EYED-002 Low Dose (721 U/mL topical insulin), EYED-002 High Dose (1442 U/mL topical insulin), EYED-002 (highest tolerated dose, 12-month) - Open Angle Glaucoma, Primary Open Angle Glaucoma | Phase 1 / Phase 2 | Enrolling by invitation | Stanford University | 90 | 2026-09-10 | 2026-10-13 |
| Treatment of LSCD With DM transplantation of a Descemet's Membrane corneal onlay, partial LSCD, transplantation of a Descemet's Membrane corneal onlay, total/near-total LSCD - Limbal Stem-cell Deficiency, Congenital Aniridia | Phase 1 | Completed | University of Minnesota | 19 | 2023-11-30 | 2026-01-08 |
| RAFT - Clinical Trial of RAFT for Aniridia Related Keratopathy RAFT-OS - Aniridia | Phase 1 / Phase 2 | Completed | University College, London | 9 | 2021-07-28 | 2025-04-30 |
| The Safety and Efficacy of Chicken Type II Collagen on Uveitis Associated With Juvenile Rheumatoid Arthritis Chicken type II collagen - Arthritis, Juvenile Rheumatoid, Uveitis | Phase 1 | Completed | National Eye Institute (NEI) | 13 | 1997-07-01 | 2008-03-04 |
Aniridia (2) · Arthritis, Juvenile (1) · Exfoliation Syndrome (1) · Glaucoma (1) · Glaucoma, Open-Angle (1) · Inflammation (1) · Iritis (1) · Limbal Stem Cell Deficiency (1) · Low Tension Glaucoma (1) · Uveitis (1)
Eye Diseases (4) · Uveal Diseases (4) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Eye Abnormalities (2) · Eye Diseases, Hereditary (2) · Genetic Diseases, Inborn (2) · Arthritis (1) · Autoimmune Diseases (1) · Connective Tissue Diseases (1) · Corneal Diseases (1) · Immune System Diseases (1) · Joint Diseases (1) · Musculoskeletal Diseases (1)
Insulin (1)
National Eye Institute (NEI) (1) · Stanford University (1) · University College, London (1) · University of Minnesota (1)
United States (3) · United Kingdom (1)
Jeffrey L Goldberg, MD PhD (1) · Julie Daniels (1) · Sajjad Ahmad (1) · Stephen Kaufman, MD (1)