7 completed, 2 unknown, 1 withdrawn. 4 Phase 2, 3 Phase 1, 2 Phase 3, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Unknown 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 2 | Completed 2 |
| Not applicable | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Intermediate Uveitis: new trials by email Literature Review of Intermediate Uveitis trials Research Report on Intermediate Uveitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravitreal Sirolimus as Therapeutic Approach to Uveitis Intravitreal injection 440mcg, Intravitreal injection of sirolimus 880mcg - Uveitis, Intermediate Uveitis | Phase 2 | Withdrawn | Stanford University | 2022-09-01 | 2023-10-26 | |
| Pilot Project: The Amplicon and Metatranscriptomic Study of Intra and Extra Intestinal Microbiome in Non-infectious Uveitis Disease Autoimmune Uveitis, Behçet Disease | Unknown | Fakultas Kedokteran Universitas Indonesia | 10 | 2019-11-01 | 2019-10-17 | |
| Variations in Retinal Nerve Fiber Layer Thickness During Uncomplicated Anterior and Intermediate Uveitis Anterior Uveitis, Intermediate Uveitis | Completed | CHU de Quebec-Universite Laval | 36 | 2016-08-01 | 2021-01-27 | |
| Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients H.P. ACTHAR SUBCUTANEOUS GEL INJECTION - Uveitis, Anterior Uveitis | Phase 4 | Completed | Tampa Bay Uveitis Center, LLC | 6 | 2016-06-30 | 2018-07-02 |
| Safety and Efficacy Study of a FAI Insert in Subjects With Chronic Non-infectious Posterior Uveitis Sham Injection, FAI Insert - Posterior Uveitis, Intermediate Uveitis | Phase 3 | Completed | EyePoint Pharmaceuticals, Inc. | 153 | 2015-06-02 | 2020-07-21 |
| Study of the Safety, Tolerability, and Bioactivity of Tocilizumab On Patients With Non-infectious UVEITIS: The STOP-UVEITIS Study Tocilizumab - Intermediate Uveitis, Posterior Uveitis | Phase 1 / Phase 2 | Unknown | University of Nebraska | 36 | 2013-03-01 | 2017-04-28 |
| Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis triamcinolone acetonide (Triesence®) - Uveitis, Intermediate Uveitis | Phase 1 / Phase 2 | Completed | Clearside Biomedical, Inc. | 11 | 2013-02-01 | 2021-02-21 |
| Sirolimus as Therapeutic Approach to Uveitis Sirolimus (rapamycin) - Uveitis, Intermediate Uveitis | Phase 1 | Completed | Johns Hopkins University | 30 | 2009-07-01 | 2018-08-20 |
| Retisert and Cataract Surgery in Patients With Severe Uveitis Retisert (fluocinolone acetonide implant) - Intermediate Uveitis, Posterior Uveitis | Not applicable | Completed | Duke University | 21 | 2006-09-01 | 2014-09-03 |
| A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Intermediate or Posterior Uveitis Dexamethasone, dexamethasone, Sham injection - Intermediate Uveitis, Posterior Uveitis | Phase 2 / Phase 3 | Completed | Allergan | 229 | 2006-05-01 | 2011-04-14 |
Uveitis, Intermediate (10) · Uveitis, Posterior (9) · Panuveitis (4) · Uveitis (4) · Uveitis, Anterior (2) · Behcet Syndrome (1) · Choroidal Effusions (1) · Giant Cell Arteritis (1) · Inflammation (1) · Ophthalmia, Sympathetic (1) · Scleritis (1) · Uveomeningoencephalitic Syndrome (1)
Eye Diseases (10) · Uveal Diseases (10) · Panuveitis (6) · Uveitis (6) · Autoimmune Diseases (2) · Autoimmune Diseases of the Nervous System (2) · Cardiovascular Diseases (2) · Immune System Diseases (2) · Nervous System Diseases (2) · Skin Diseases (2) · Skin Diseases, Vascular (2) · Skin and Connective Tissue Diseases (2) · Vascular Diseases (2) · Vasculitis (2) · Arteritis (1)
salicylhydroxamic acid (2) · Adrenal Cortex Hormones (1) · Adrenocorticotropic Hormone (1) · Contraceptives, Oral (1) · Dexamethasone (1) · Fluocinolone Acetonide (1) · Intravitreal Injections (1) · Sirolimus (1) · Triamcinolone (1) · Triamcinolone Acetonide (1) · tocilizumab (1)
Allergan (1) · CHU de Quebec-Universite Laval (1) · Clearside Biomedical, Inc. (1) · Duke University (1) · EyePoint Pharmaceuticals, Inc. (1) · Fakultas Kedokteran Universitas Indonesia (1) · Johns Hopkins University (1) · Stanford University (1) · Tampa Bay Uveitis Center, LLC (1) · University of Nebraska (1)
United States (7) · Canada (2) · India (2) · Australia (1) · Austria (1) · Brazil (1) · Czechia (1) · France (1) · Germany (1) · Greece (1) · Indonesia (1) · Israel (1) · Poland (1) · Portugal (1) · South Africa (1)
Quan D Nguyen, MD, MSc (3) · Flavio Leonin Jr., MD (1) · Glenn J Jaffe, MD (1) · Grace L Clarke (1) · Ratna Sitompul, Professor (1) · Simon Couture, Doctor (1) · Thomas Ciulla, MD (1)
PMID 18639220, PMID 21220619, PMID 23411886, PMID 23761087, PMID 25918559, PMID 27980877, PMID 33042579, PMID 37172782, PMID 38027419