2 active not recruiting, 2 completed, 1 withdrawn. 5 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 5 | Active not recruiting 2, Completed 2, Withdrawn 1 |
Follow Hypergammaglobulinemia: new trials by email Literature Review of Hypergammaglobulinemia trials Research Report on Hypergammaglobulinemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dendritic Cell DKK1 Vaccine for Monoclonal Gammopathy and Stable or Smoldering Myeloma DKK1 - Monoclonal Gammopathy, Smoldering Myeloma | Early Phase 1 | Withdrawn | Case Comprehensive Cancer Center | 2023-12-01 | 2023-08-18 | |
| Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma Leflunomide, Quality-of-Life Assessment - Smoldering Plasma Cell Myeloma | Early Phase 1 | Active not recruiting | City of Hope Medical Center | 1 | 2020-10-08 | 2026-01-05 |
| Personalized Vaccine in Treating Patients With Smoldering Multiple Myeloma Biopsy Specimen Radiography, Lenalidomide, Vaccine Therapy - Smoldering Plasma Cell Myeloma | Early Phase 1 | Completed | M.D. Anderson Cancer Center | 30 | 2018-12-21 | 2025-12-19 |
| Pembrolizumab in Treating Patients With Intermediate or High-Risk Smoldering Multiple Myeloma Laboratory Biomarker Analysis, Pembrolizumab - Smoldering Plasma Cell Myeloma | Early Phase 1 | Active not recruiting | M.D. Anderson Cancer Center | 20 | 2016-07-20 | 2026-07-17 |
| Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases Pemetrexed - Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders | Early Phase 1 | Completed | Northwestern University | 15 | 2007-01-01 | 2021-09-08 |
Smoldering Multiple Myeloma (4) · Neoplasms, Plasma Cell (2) · Blast Crisis (1) · Brain Neoplasms (1) · Burkitt Lymphoma (1) · Central Nervous System Neoplasms (1) · Congenital Abnormalities (1) · Hodgkin Disease (1) · Immunoblastic Lymphadenopathy (1) · Immunoglobulin Light-chain Amyloidosis (1) · Intraocular Lymphoma (1) · Leukemia (1) · Leukemia, Biphenotypic, Acute (1) · Leukemia, Hairy Cell (1) · Leukemia, Large Granular Lymphocytic (1)
Blood Protein Disorders (5) · Hematologic Diseases (5) · Hemic and Lymphatic Diseases (5) · Immune System Diseases (5) · Immunoproliferative Disorders (5) · Neoplasms (5) · Paraproteinemias (4) · Precancerous Conditions (4) · Neoplasms by Histologic Type (2) · Amyloidosis (1) · Blood Coagulation Disorders (1) · Blood Platelet Disorders (1) · Bone Marrow Diseases (1) · Bone Marrow Neoplasms (1)
Immunotherapy, Active (1) · Leflunomide (1) · Lenalidomide (1) · Pemetrexed (1) · pembrolizumab (1)
M.D. Anderson Cancer Center (2) · Case Comprehensive Cancer Center (1) · City of Hope Medical Center (1) · Northwestern University (1)
United States (5)
Ehsan Malek, MD (1) · Jeffrey J. Raizer, MD (1) · Krina Patel (1) · Michael A Rosenzweig (1) · Neeraj Saini, MD (1)