6 completed, 2 recruiting, 2 unknown, 1 suspended. 7 Phase 1, 5 Phase 2, 1 Early Phase 1, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 4, Recruiting 2, Terminated 1 |
| Phase 2 | 5 | Completed 4, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
| Not applicable | 1 | Unknown 1 |
| Phase 3 | 1 | Suspended 1 |
Follow Immunotherapy, Active: new trials by email Literature Review of Immunotherapy, Active trials Research Report on Immunotherapy, Active
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer Ipilimumab, Pembrolizumab, Vaccine Therapy - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8 | Phase 1 | Recruiting | Emory University | 18 | 2025-12-02 | 2026-01-26 |
| Efficacy and Safety of Autologous Peptide-induced Active Immunity in AML Maintenance Therapy Active Immunotherapy, after 6 courses of routine consolidation chemotherapy, during 6 courses of routine consolidation chemotherapy - Acute Myeloid Leukemia, Personalized Active Immunotherapy | Phase 1 | Recruiting | Fujian Medical University Union Hospital | 90 | 2024-09-01 | 2026-05-01 |
| TACE Combined With "Target Immune" Therapy for First-line Treatment in the Treatment of Intrahepatic Cholangiocarcinoma Transcatheter arterial chemoembolization, Multi-target Drug Therapy, Immunocheckpoint Inhibitor Therapy - Intrahepatic Cholangiocarcinoma | Not applicable | Unknown | The Central Hospital of Lishui City | 98 | 2022-03-01 | 2022-02-21 |
| Personalized Vaccine in Treating Patients With Smoldering Multiple Myeloma Biopsy Specimen Radiography, Lenalidomide, Vaccine Therapy - Smoldering Plasma Cell Myeloma | Early Phase 1 | Completed | M.D. Anderson Cancer Center | 30 | 2018-12-21 | 2025-12-19 |
| Mix Vaccine for Metastatic Sarcoma Patients Mix vaccine - Metastatic Sarcoma, Reaction - Mixed Vaccine | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2017-11-30 | 2019-09-12 |
| Mix Vaccine for Metastatic Kidney Cancer Mix vaccine - Metastasis From Malignant Tumor of Kidney (Disorder), Reaction - Mixed Vaccine | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2017-11-30 | 2019-09-12 |
| Mix Vaccine for Metastatic Colorectal Cancer Mix vaccine - Metastatic Colorectal Cancer, Reaction - Mixed Vaccine | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2017-11-30 | 2019-09-12 |
| Outcomes With Immune Checkpoint Inhibitor for Patients With Non-Small-Cell Lung Cancer and Stable Brain Metastases immune therapy - Non Small Cell Lung Cancer | Completed | Hunan Province Tumor Hospital | 200 | 2017-11-03 | 2023-04-10 | |
| Phase I/II Study of Immune Therapy After Allograft in Patients With Myeloid Hemopathy recwt1-A10+AS01B - Acute Myeloid Leukemia, Chronic Myeloid Leukemia | Phase 1 / Phase 2 | Completed | Institut Paoli-Calmettes | 2 | 2013-03-01 | 2015-03-20 |
| Vaccine Therapy in Treating Patients Who Are Undergoing Surgery for Stage IB, Stage II, or Stage IIIA Non-Small Cell Lung Cancer autologous tumor cell vaccine, therapeutic autologous dendritic cells, adjuvant therapy - Lung Cancer | Phase 1 | Terminated | Jonsson Comprehensive Cancer Center | 15 | 2005-02-01 | 2008-01-28 |
| Idiotype Vaccine for Low-Grade Non-Hodgkin's Lymphoma FavId (Id-KLH) active immunotherapy - Lymphoma, Low-Grade | Phase 2 | Unknown | Favrille | 22 | 2001-03-01 | 2005-06-24 |
| GM-CSF With or Without Vaccine Therapy After Combination Chemotherapy and Rituximab as First-Line Therapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma autologous immunoglobulin idiotype-KLH conjugate vaccine, cyclophosphamide, doxorubicin hydrochloride - Lymphoma | Phase 3 | Suspended | Favrille | 480 | 2013-12-18 |
Carcinoma, Non-Small-Cell Lung (2) · Leukemia, Myeloid, Acute (2) · Lymphoma (2) · Breast Neoplasms (1) · Cholangiocarcinoma (1) · Colorectal Neoplasms (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Lung Neoplasms (1) · Lymphoma, Large B-Cell, Diffuse (1) · Lymphoma, Non-Hodgkin (1) · Myelodysplastic Syndromes (1) · Sarcoma (1) · Smoldering Multiple Myeloma (1) · Triple Negative Breast Neoplasms (1)
Fuda Cancer Hospital, Guangzhou (3) · Favrille (2) · Emory University (1) · Fujian Medical University Union Hospital (1) · Hunan Province Tumor Hospital (1) · Institut Paoli-Calmettes (1) · Jonsson Comprehensive Cancer Center (1) · M.D. Anderson Cancer Center (1) · The Central Hospital of Lishui City (1)
China (5) · United States (5) · France (1)
John F. Bender, PharmD (1) · Keerthi Gogineni, MD, MSHP (1) · Krina Patel (1) · Meijuan Huang (1) · Michael D. Roth, MD (1) · Xihui Ying, MD. (1) · Yongchang C Zhang, MD (1)
P30CA138292 (1), R44CA257278 (1)