93 completed, 34 recruiting, 14 not yet recruiting, 11 unknown. 100 Not applicable, 24 Phase 1, 12 Phase 4, 6 Phase 2, 4 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Private-sector Access to Testing for Health Sustainability Low HIVST kit subsidy, High HIVST kit subsidy - HIV Prevention | Not applicable | Not yet recruiting | University of California, San Francisco | 200 | 2027-01-15 | 2026-09-11 |
| Are Louisiana Pharmacists PrEPared? Implementing Training and an Active PrEP (Pre-Exposure Prophylaxis) Prescribing Surveillance Program Education and Mentoring for Prescribing Pharmacists - HIV Prevention | Not yet recruiting | Xavier University of Louisiana. | 75 | 2027-01-01 | 2026-07-31 | |
| A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs LINKED, Group Intervention - Substance Use, HIV Prevention | Not applicable | Not yet recruiting | NYU Langone Health | 398 | 2027-01-01 | 2026-02-13 |
| Examining Migration, Social Bonds, Transnationalism, and HIV Prevention Pathways Among African Immigrants. Relationship-Centered HIV Prevention Intervention Component (Proof-of-Concept) - HIV Prevention, HIV Testing | Not applicable | Not yet recruiting | State University of New York at Buffalo | 144 | 2026-12-04 | 2026-10-16 |
| mHealth Service Linkage for Young Adults Impacted by the Criminal Legal System LYNX, Standard of Care - HIV Prevention, Substance Use | Not applicable | Not yet recruiting | University of Pittsburgh | 50 | 2026-12-01 | 2026-10-20 |
| Pharmacies in HIV Prevention: Fellowship, Fundamentals, and Sustainable Finances Virtual Community of Practice, Enhanced Standard of Care - HIV Prevention | Not applicable | Not yet recruiting | University of Washington | 500 | 2026-11-01 | 2026-09-18 |
| Community-based Outreach and Navigation for Nurse-led Engagement in HIV Care and Treatment CONNECT (status-neutral, nurse-led on-site HIV service delivery), Standard of Care (referral-based outreach) - HIV Infections, HIV Prevention | Not applicable | Not yet recruiting | Donaldson Conserve | 360 | 2026-11-01 | 2026-10-13 |
| Leveraging Video Logs as a Bridge to Pre-exposure Prophylaxis (PrEP) With Tailored Messaging to Black Women and Their Healthcare Providers in Texas. Video-log (vlog) series with videos tailored to cisgender Black women or to healthcare providers - HIV Prevention | Early Phase 1 | Not yet recruiting | The University of Texas Medical Branch, Galveston | 78 | 2026-10-31 | 2026-09-04 |
| PrEP & Soccer: A Program for Pharmacy Chains to Increase PrEP Awareness and Access Among Men PrEP & Soccer PrEP Navigation, CVS Health brochure - HIV Prevention, Latino Men Who Have Sex With Men | Not applicable | Not yet recruiting | University of Miami | 800 | 2026-10-30 | 2026-08-19 |
| Combatting HIV Or Other STIs Early (CHOOSE) Standard of care and PrEP Choice at Enrollment, Standard of care followed by PrEP Choice at Month 9 - HIV, STIs | Not applicable | Recruiting | Westat | 200 | 2026-09-16 | 2026-10-09 |
| Evaluating the Safety and Immunogenicity of Polyvalent DNA and Recombinant gp120 Protein HIV Vaccine (PDPHV) in Healthy, HIV-uninfected Adults PDPHV Plasmid DNA Vaccines (env (A, B, C, A/E)/gag (C)), PDPHV Recombinant Protein Vaccines (gp120 (A, B, C, A/E)), Alhydrogel adjuvant - HIV Prevention | Phase 2 | Not yet recruiting | Worcester HIV Vaccine | 126 | 2026-09-01 | 2026-06-30 |
| PEP/PrEP Via Pharmacist-Prescribing Implementation (PEPPI) PEPPI Pharmacies - HIV Prevention, HIV Pre-exposure Prophylaxis | Not applicable | Recruiting | EMPOWERX INC | 195 | 2026-08-01 | 2026-07-07 |
| Pre-exposure Prophylaxis (PrEP) Adherence for Black MSM C4 Program, C4 + 3MV Program - HIV Prevention | Not applicable | Not yet recruiting | Yale University | 500 | 2026-08-01 | 2026-05-18 |
| Leveraging Chatbot to Improve PrEP in the Southern United States A chatbot designed to promote PrEP awareness and uptake for Black MSM, General educational messages - HIV Prevention, PrEP Awareness | Not applicable | Recruiting | Yale University | 145 | 2026-07-13 | 2026-09-23 |
| RESTORE Study R61 Phase: Recovery and Engagement for Stimulant Users on Re-entry DynamiCare, Patient Navigation (PN) - HIV, Stimulant Use Disorder | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 40 | 2026-06-01 | 2026-06-15 |
| Initiative for Chinese Sex Workers to Promote Wellbeing and Improve HIV Prevention by Reducing intersEctional Stigma INSPIRE Initiative, Standard of Care - HIV Prevention, Wellbeing | Not applicable | Not yet recruiting | NYU Langone Health | 70 | 2026-06-01 | 2026-05-29 |
| Mobile Vehicle-Based Delivery of Lenacapavir Pre-Exposure Prophylaxis in Los Angeles County Community-based healthcare delivery, Lenacapavir - HIV Prevention | Recruiting | University of California, Los Angeles | 100 | 2026-04-21 | 2026-04-23 | |
| Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation Interactive Digital PrEP Toolkit - HIV Prevention, HIV Risk | Not applicable | Recruiting | University of Alabama at Birmingham | 125 | 2026-04-20 | 2026-06-23 |
| A Self-administered PrEP Decisional Aid for Dissemination With HIV Self-test Kits (DASH) PrEP Decisional Aid for dissemination with Self-administered HIV test kits (DASH) - Pre-Exposure Prophylaxis (PrEP), HIV Prevention | Not applicable | Enrolling by invitation | University of Michigan | 170 | 2026-04-17 | 2026-06-03 |
| Peer-led Service Delivery Model for Pregnant and Lactating Adolescent Girls and Young Women in Zimbabwe Peers who are stars - HIV Prevention, Contraceptive Usage | Not applicable | Not yet recruiting | University College, London | 600 | 2026-04-01 | 2026-04-22 |
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Behavior (32) · Communicable Diseases (28) · Genital Diseases (28) · Urogenital Diseases (28) · Infections (27) · Blood-Borne Infections (19) · RNA Virus Infections (19) · Virus Diseases (19) · Immune System Diseases (18) · Immunologic Deficiency Syndromes (18) · Lentivirus Infections (18) · Retroviridae Infections (18) · Sexually Transmitted Diseases (18) · Sexually Transmitted Diseases, Viral (18) · Chemically-Induced Disorders (11)
Tenofovir (16) · Standard of Care (14) · Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (12) · Emtricitabine (9) · emtricitabine tenofovir alafenamide (6) · Gels (5) · Vaginal Creams, Foams, and Jellies (3) · Dapivirine (2) · Lamivudine (2) · Racivir (2) · lenacapavir (2) · tenofovir alafenamide (2) · Behavior Therapy (1) · Cognitive Behavioral Therapy (1) · Counseling (1)
CONRAD (9) · Johns Hopkins University (9) · University of North Carolina, Chapel Hill (9) · University of California, Los Angeles (7) · University of Washington (6) · Institute of HIV Research and Innovation Foundation, Thailand (5) · Massachusetts General Hospital (5) · Microbicide Trials Network (5) · Public Health Foundation Enterprises, Inc. (4) · University of California, San Francisco (4) · Yale University (4) · Emory University (3) · Florida International University (3) · Hilary L Surratt, PhD (3) · Ministry of Health, Rwanda (3)
United States (102) · South Africa (20) · Malawi (9) · Uganda (9) · Thailand (8) · Kenya (7) · Zimbabwe (7) · Brazil (3) · Peru (3) · Rwanda (3) · Australia (2) · Canada (2) · Armenia (1) · Dominican Republic (1) · Eswatini (1)
Craig Hendrix, MD (4) · Susan Buchbinder, MD (4) · Nittaya Phanuphak, MD,PhD. (3) · Carol Golin, MD (2) · Hilary L Surratt, PhD (2) · Lauren Hill, PhD (2) · Raphael Landovitz, MD (2) · Vincent Mutabazi, M.D. (2) · Aaron Fox (1) · Adam W Carrico, PhD (1) · Akarin Hiransuthikul, MD,MSc (1) · Albert Liu (1) · Alexander J Lankowski, MD (1) · Alexandra Minnis, PhD (1) · Alida Bouris, PhD (1)
PMID 41232107, PMID 17403495, PMID 21091279, PMID 21368592, PMID 22339731, PMID 22900504, PMID 22943559, PMID 22972843, PMID 23377730, PMID 25350119, PMID 25350130, PMID 25942472, PMID 26227279, PMID 26544581, PMID 27247202, PMID 29957723, PMID 30045702, PMID 30154071, PMID 30222141, PMID 30507409, PMID 30666522, PMID 30683103, PMID 30782948, PMID 31350241, PMID 31473167, PMID 31692269, PMID 32065631, PMID 32524700, PMID 32766890, PMID 32773376, PMID 32773383, PMID 32869511, PMID 32915162, PMID 32933510, PMID 33044687, PMID 33251157, PMID 33278181, PMID 33325126, PMID 33371779, PMID 33389318, PMID 33539761, PMID 33749321, PMID 34256725, PMID 34311754, PMID 34851726, PMID 34991141, PMID 34995162, PMID 35162690, PMID 35255859, PMID 35324081
UM1AI068615 (4), UM1AI068633 (4), UM1AI106707 (4), P01HD112215 (3), U19AI113127 (3), 5UM1AI068633 (2), R01MH109320 (2), U19AI082637 (2), 5UG3HD096914 (1), DP1DA060602 (1), K01MH121186 (1), K23MH102118 (1), K23MH119976 (1), K23MH123335 (1), K23MH126781 (1)