6 completed, 5 recruiting, 2 unknown, 1 enrolling by invitation. 10 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 3, Recruiting 3, Not yet recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Chemsex: new trials by email Literature Review of Chemsex trials Research Report on Chemsex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| JomCare Study - A Harm Reduction Study JomCare is a smartphone-based just-in-time adaptive intervention (JITAI) for chemsex-related harm reduction. - HIV, Substance Abuse Disorder | Not applicable | Not yet recruiting | University of Connecticut | 482 | 2026-11-01 | 2026-10-09 |
| Acceptance and Commitment Therapy for Chemsex ACT-for-chemsex, Treatment as Usual (TAU) - Chemsex | Not applicable | Withdrawn | University of Alabama at Birmingham | 2025-12-01 | 2025-12-15 | |
| Integrating Sexual Pleasure Into Harm Reduction Services for Men Who Have Sex With Men and Transgender Persons Who Engage in Chemsex or Substance Use in Thailand Pleasuremeter-guided qualitative interview, Pleasuremeter-based sexual pleasure discussion integrated with harm reduction services - HIV Prevention, Substance Use | Not applicable | Recruiting | Institute of HIV Research and Innovation Foundation, Thailand | 300 | 2025-05-01 | 2026-04-08 |
| Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV Ketamine, Psychotherapy - Methamphetamine Use Disorder | Phase 2 | Completed | Nicky Mehtani, MD, MPH | 17 | 2025-03-04 | 2026-08-12 |
| Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: A Pre-Implementation Study Self-administered questionnaire assessment, Semi-structured in-depth interviews (IDIs), Development and refinement of harm reduction model - HIV Prevention, Substance Use | Recruiting | Institute of HIV Research and Innovation Foundation, Thailand | 76 | 2025-02-17 | 2026-04-06 | |
| Faisability and Efficacity of the Reinforced Communautary Support Program (PARC) on the Complications of Chemsex Reinforced Communautary Support Program (PARC) - Chemsex, Addiction | Not applicable | Unknown | Assistance Publique - Hôpitaux de Paris | 60 | 2024-09-20 | 2024-09-24 |
| Chemsex Health Evaluation With Extended Release System for HIV Treatment Cabenuva 600/900, Self administered questionnaires, Semi-directed interview - HIV | Unknown | Clinique Médicale L'Actuel | 50 | 2024-08-01 | 2024-08-21 | |
| Effectiveness of tDCS on Reducing Craving in Patients Practicing Chemsex: a Single-center, Double-blind, Randomized Controlled Pilot Trial tDCS, Assessment of risk behaviours, Scales - Chemsex | Not applicable | Recruiting | Centre Hospitalier Universitaire Dijon | 40 | 2024-07-29 | 2026-09-02 |
| Effectiveness of ACT for Problematic Chemsex Acceptance and Commitment Therapy (ACT) - Hypersexuality, Compulsive Sexual Behavior | Not applicable | Completed | Universidad Europea de Madrid | 36 | 2024-06-01 | 2026-04-13 |
| Pre-implementation Study to Develop Trans-tailored Services for Transgender Persons in Relation to chemsEX Understanding of chemsex patterns, impacts, and service needs among transgender persons - Substance Use, HIV Prevention | Recruiting | Institute of HIV Research and Innovation Foundation, Thailand | 50 | 2024-05-01 | 2026-04-06 | |
| Acceptance and Commitment Therapy for Problematic Chemsex Acceptance and Commitment Therapy (ACT) - Hypersexuality, Compulsive Sexual Behavior | Not applicable | Completed | Universidad Europea de Madrid | 5 | 2024-03-01 | 2025-04-23 |
| The Implementation of a Trans-tailored Harm Reduction Service for Transgender Persons in Relation to chemsEX and Substance Use (iT-REX) Transgender-tailored Harm Reduction Service - HIV Prevention, Substance Use | Not applicable | Recruiting | Institute of HIV Research and Innovation Foundation, Thailand | 140 | 2024-02-01 | 2026-04-06 |
| The Use of Cognitive Mindfulness for Chemsex mindful cognitive intervention - Substance Use | Not applicable | Completed | London Metropolitan University | 29 | 2022-03-05 | 2023-07-03 |
| Drug Use During Sex and Its Impact on Taking PrEP (Pre-Exposure Prophylaxis) : CONSUME self-questionnaire - Drug Dependence | Completed | Assistance Publique - Hôpitaux de Paris | 100 | 2021-03-18 | 2022-08-30 | |
| Clinical Trial to Evaluate Pharmacological Interactions Between γ-hydroxybutyrate (GHB) and Cobicistat Cobicistat 150 MG, Placebo, GHB - Pharmacokinetic Interactions, HIV | Phase 1 | Completed | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 12 | 2020-01-30 | 2020-07-22 |
| Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis Tenofovir Disoproxil Fumarate 300 MG Oral Tablet - HIV Infection Primary, Hepatitis, Viral, Human | Enrolling by invitation | Hospitales Universitarios Virgen del Rocío | 500 | 2020-01-01 | 2023-09-22 | |
| PrEP and Consumptions self-administered questionnaire - Psychoactive Substance Use, Mood Disorders | Not applicable | Terminated | University Hospital, Montpellier | 237 | 2018-01-03 | 2021-12-30 |
Substance-Related Disorders (7) · Sexually Transmitted Diseases (5) · Harm Reduction (4) · Compulsive Sexual Behavior Disorder (2) · Psychological Well-Being (2) · Sexuality (2) · Behavior, Addictive (1) · Hepatitis (1) · Hepatitis, Viral, Human (1) · Homosexuality (1) · Infections (1) · Mental Disorders (1) · Mood Disorders (1) · Sexual Behavior (1)
Behavior (17) · Sexual Behavior (16) · Mental Disorders (9) · Chemically-Induced Disorders (7) · Genital Diseases (6) · Urogenital Diseases (6) · Communicable Diseases (5) · Disease Attributes (5) · Infections (5) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Compulsive Behavior (3) · Impulsive Behavior (3) · Behavior, Addictive (2) · Personal Satisfaction (2)
Acceptance and Commitment Therapy (2) · Therapeutics (2) · Cobicistat (1) · Emtricitabine (1) · Growth and Development (1) · Ketamine (1) · Psychotherapy (1) · Sodium Oxybate (1) · Tablets (1) · Tenofovir (1) · Transcranial Direct Current Stimulation (1) · Weights and Measures (1)
Institute of HIV Research and Innovation Foundation, Thailand (4) · Assistance Publique - Hôpitaux de Paris (2) · Universidad Europea de Madrid (2) · Centre Hospitalier Universitaire Dijon (1) · Clinique Médicale L'Actuel (1) · Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia (1) · Hospitales Universitarios Virgen del Rocío (1) · London Metropolitan University (1) · Nicky Mehtani, MD, MPH (1) · University Hospital, Montpellier (1) · University of Alabama at Birmingham (1) · University of Connecticut (1)
France (4) · Spain (4) · Thailand (4) · United States (2) · Canada (1) · Malaysia (1) · United Kingdom (1)
Francisco Montesinos, Ph.D. (2) · Nittaya Phanuphak, MD,PhD. (2) · Akarin Hiransuthikul, MD,MSc (1) · Jakkrapatara Boonruang, MD (1) · Jason Szabo, MD, PhD (1) · Karin Neukam, PharmD, PhD (1) · Marta Herrero Romero, MD, PhD (1) · Nicky Mehtani, MD MPH (1) · Roman Shrestha, PhD (1)
PMID 15812614, PMID 16443717, PMID 18686156, PMID 20217471, PMID 22530986, PMID 24290208, PMID 25689576, PMID 26372268, PMID 27852287, PMID 27855594, PMID 29846139, PMID 30021714, PMID 30297094, PMID 30513473, PMID 31230464, PMID 31375976, PMID 31860172, PMID 32139497, PMID 33329083, PMID 34218004, PMID 34561695, PMID 40850924, PMID 8993716
2019 (1), 2KL2TR001870 (1), R01DA061661 (1)