123 completed, 7 unknown, 5 terminated, 3 not yet recruiting. 39 Phase 3, 36 Phase 2, 27 Phase 4, 23 Not applicable, 19 Phase 1.
Follow abacavir: new trials by email Literature Review of abacavir trials Research Report on abacavir
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Adaptive Platform Trial for Evaluation of Novel Treatment Regimens in Children and Adolescents With HIV in Africa Dolutegravir (DTG), Abacavir (ABC), Lamivudine (3TC) - HIV Infection | Phase 3 | Not yet recruiting | University College, London | 800 | 2026-11-01 | 2026-08-28 |
| Preliminary Testing and Development of a Short Digital Intervention for Patients on Waiting Lists for Psychological Treatment Digital therapy program (short), Digital therapy program (long), Mental health advice - Depression, Anxiety | Not applicable | Enrolling by invitation | University of Oslo | 80 | 2026-03-24 | 2026-05-01 |
| Research on the Psychological Status of Patients With HIV-1 Infection All kinds of INSTI medications, All kinds of conventional medications - HIV-1-infection, Anxiety Depression | Not yet recruiting | Shanxi Bethune Hospital | 500 | 2025-08-01 | 2025-07-23 | |
| Moving on After Breast Cancer Trial for Depressed Breast Cancer Survivors in Pakistan Non-specialist delivered Low intensity guided self-help (Khushi and Khatoon), Moving on After Breast Cancer (ABC) plus, Standardised pharmacological treatment (antidepressants) - Major Depressive Disorder (MDD), Breast Cancer Survivor | Not applicable | Recruiting | Pakistan Institute of Living and Learning | 26376 | 2025-06-13 | 2026-03-18 |
| STARLITE for Unresectable High-Grade Gliomas Magnetic Resonance (MR)-guided Laser Interstitial Thermal Therapy (LITT), Abacavir, Lamivudine - High Grade Glioma | Phase 1 | Recruiting | University of Miami | 24 | 2025-04-15 | 2026-06-25 |
| RolloverTreatment With Triumeq for People With ALS Following the Lighthouse II Trial Abacavir 600mg, Lamivudine 300mg and Dolutegravir 50mg (Triumeq) - Amyotrophic Lateral Sclerosis, ALS | Phase 3 | Terminated | Macquarie University, Australia | 12 | 2024-11-15 | 2025-06-08 |
| Active Balance and Cardio Care Intervention on Physical and Cardiovascular Health in People With Chronic Stroke Virtual reality based dance group, Active Comparator: Control - Chronic Stroke | Not applicable | Not yet recruiting | University of Illinois at Chicago | 120 | 2024-10-01 | 2023-10-18 |
| All Children in Focus (ABC) 0-2 Years: A Pilot Study ABC 0-2 years, waiting list - Parent-Child Relations, Parenting | Not applicable | Completed | Ersta Sköndal University College | 300 | 2023-02-01 | 2023-09-14 |
| SSIs for Mental Health and Loneliness Overcoming Loneliness three-week intervention, Overcoming Loneliness single-session intervention, Single-session "Sharing Feelings" program - Loneliness, Mental Health Issue | Not applicable | Completed | University of California, Irvine | 4370 | 2022-12-04 | 2024-07-22 |
| Inhibition of Reverse Transcription in Aicardi-Goutières Syndrome Abacavir (ABC), Lamivudine (3TC), Abacavir (ABC)+Lamivudine (3TC)+Zidovudine (AZT) - Aicardi-Goutières Syndrome | Phase 2 | Completed | University of Edinburgh | 13 | 2022-08-24 | 2024-05-09 |
| Abacavir, Dolutegravir and Lamivudine Dispersible Tablets (60 mg/5 mg/30 mg) abacavir, dolutegravir and lamivudine dispersible tablets, Triumeq Dispersible Tablets 5 mg GSK1349572 [Dolutegravir]/ 60 mg Abacavir/ 30 mg Lamivudine - HIV-1-infection | Early Phase 1 | Completed | Mylan Inc. | 43 | 2021-08-01 | 2022-03-25 |
| Contribution of Dolutegravir to Obesity and Cardiovascular Disease Dolutegravir 50 MG, Antiretroviral/Anti HIV - HIV-1-infection, Antiviral Drug Adverse Reaction | Phase 4 | Completed | Augusta University | 10 | 2020-09-17 | 2023-07-27 |
| The Pharmacokinetics, Safety, and Tolerability of Abacavir/Dolutegravir/Lamivudine Dispersible and Immediate Release Tablets in HIV-1-Infected Children Less Than 12 Years of Age Abacavir (ABC)/Dolutegravir (DTG)/Lamivudine (3TC) Dispersible Tablets, Abacavir (ABC)/Dolutegravir (DTG)/Lamivudine (3TC) Immediate Release Tablets (Immediate release) - HIV Infections | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 57 | 2020-09-09 | 2023-06-27 |
| Attachment and Biobehavioral Catch-up for Depression Attachment and Biobehavioral Catch-up (ABC) Intervention - Depressive Symptoms, Anxiety Symptoms | Not applicable | Completed | University of California, San Francisco | 42 | 2020-08-01 | 2024-07-22 |
| Clinical Trial to Evaluate the Efficacy, Pharmacokinetics (PK) Interactions and Safety of Dolutegravir Plus 2 Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV-1-Infected Solid Organ Transplant Patients Lamivudine 300 MG, Abacavir 600 MG, Dolutegravir 50 mg - HIV-1-infection, Solid Organ Transplant | Phase 4 | Completed | Fundacion Clinic per a la Recerca Biomédica | 19 | 2018-04-13 | 2025-09-30 |
| Viral and Antiretroviral Dynamics in HIV-1 Mother-to-Child Transmission Fluids Tenofovir Disoproxil Fumarate (TDF) 300 mg + Lamivudine (3TC) 300 mg + Efavirenz (EFV) 600 mg, Abacavir (ABC) 600 mg + Lamivudine (3TC) 300 mg + Efavirenz (EFV) 600 mg, Zidovudine (AZT) 300 mg + Lamivudine (3TC) 150 mg twice daily + Efavirenz (EFV) 600 mg once daily - Human Immunodeficiency Virus Infection | Completed | Obafemi Awolowo University | 194 | 2017-12-22 | 2020-10-14 | |
| Switching From Tenofovir Disoproxil Fumarate to Abacavir or Tenofovir Alafenamide tenofovir alafenamide, abacavir - Renal Insufficiency,Chronic, Hiv | Phase 4 | Unknown | Erasmus Medical Center | 80 | 2016-10-01 | 2020-01-28 |
| Safety and Tolerability of Antiretroviral (Triumeq) in Patients With Amyotrophic Lateral Sclerosis (ALS). Triumeq - Amyotrophic Lateral Sclerosis | Phase 2 | Completed | Neuroscience Trials Australia | 43 | 2016-10-01 | 2019-08-22 |
| Study to Evaluate the Efficacy of MONotherapy of TiviCAY® Versus a Triple Therapy in HIV-1-infected Patients dolutegravir 50mg +abacavir 600mg +lamivudine 300mg, dolutegravir - HIV | Phase 3 | Terminated | Centre Hospitalier Régional d'Orléans | 158 | 2015-12-23 | 2018-11-13 |
| Reverse Transcriptase Inhibitors in AGS Reverse transcriptase inhibitors: Zidovudine, Lamivudine, Abacavir - Aicardi-Goutières Syndrome (AGS) | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 11 | 2015-09-10 | 2025-09-05 |
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HIV Infections (100) · Acquired Immunodeficiency Syndrome (15) · Infections (12) · Lipodystrophy (6) · Depression (4) · Anxiety Disorders (3) · Tuberculosis (3) · AIDS Dementia Complex (2) · Amyotrophic Lateral Sclerosis (2) · Cardiovascular Diseases (2) · HIV-Associated Lipodystrophy Syndrome (2) · Hepatitis B (2) · Hypersensitivity (2) · Patient Compliance (2) · AIDS-Related Complex (1)
National Institute of Allergy and Infectious Diseases (NIAID) (36) · Glaxo Wellcome (28) · ViiV Healthcare (10) · GlaxoSmithKline (5) · Kirby Institute (5) · Gilead Sciences (4) · ANRS, Emerging Infectious Diseases (2) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (2) · Duke University (2) · Germans Trias i Pujol Hospital (2) · University of California, San Diego (2) · Aarhus University Hospital (1) · Assistance Publique - Hôpitaux de Paris (1) · Augusta University (1) · Bayside Health (1)
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PMID 24326304, PMID 33901188, PMID 24979445, PMID 32829410, PMID 38160309, PMID 11306155, PMID 14668455, PMID 14668456, PMID 14669723, PMID 15115831, PMID 15187476, PMID 16048984, PMID 16103764, PMID 16267764, PMID 16280696, PMID 16287792, PMID 16470119, PMID 16810109, PMID 16816555, PMID 16905783, PMID 16988514, PMID 17109339, PMID 17174704, PMID 17310819, PMID 17357053, PMID 17662759, PMID 17726714, PMID 18176329, PMID 18193496, PMID 18215978, PMID 18256392, PMID 18366444, PMID 18795962, PMID 18977721, PMID 18989231, PMID 19020325, PMID 19299471, PMID 19696651, PMID 19842973, PMID 19952143, PMID 20001518, PMID 20002783, PMID 20087154, PMID 20102271, PMID 20121419, PMID 20146627, PMID 20418798, PMID 20467286, PMID 20569064, PMID 20632458
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