19 unknown. 19 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 19 | Unknown 19 |
| Phase 2 | 6 | Unknown 6 |
Follow Hepatitis B: new trials by email Literature Review of Hepatitis B trials Research Report on Hepatitis B
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study to Evaluate the Efficacy of TQA3038 Injection in Patients With Chronic Hepatitis B TQA3038 injection/placebo, Nucleotide drugs Control group - Hepatitis B, Chronic | Phase 1 / Phase 2 | Unknown | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 162 | 2024-06-01 | 2024-06-11 |
| A Clinical Trial of TQA3038 Injection in Healthy Adult Subjects TQA3038 injection, TQA3038 injection matching placebo - Chronic Hepatitis b | Phase 1 | Unknown | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 54 | 2023-11-30 | 2023-12-05 |
| Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy Subjects Test drug XT1061 capsules and placebo,Single dose group, Test drug XT1061 capsules and placebo，Multiple dosing group, Test drug XT1061 capsules and placebo，Food Impact Group - Chronic Hepatitis b | Phase 1 | Unknown | Xi'an Xintong Pharmaceutical Research Co.,Ltd. | 128 | 2023-07-18 | 2024-02-28 |
| A Study to Evaluate Safety and Immunogenicity of APV006 in Healthy Adults DTaP-HepB-IPV-Hib vaccine - Diphtheria, Tetanus | Phase 1 | Unknown | LG Chem | 42 | 2023-07-17 | 2023-07-19 |
| Autologous T-cells Transfected With mRNA Encoding HBV-TCR T Cell Therapy in Combination With NUC for Chronic Hepatitis B TCR-T - Chronic Hepatitis B | Phase 1 | Unknown | Beijing 302 Hospital | 20 | 2023-06-01 | 2023-06-15 |
| Clinical Study to Evaluate the Safety, Tolerance and Pharmacokinetic Characteristics of Single Administration of HRS-5635 Injection in Chinese Healthy Subjects and the Safety, Tolerance, Pharmacokinetics and Antiviral Effect of Multiple Administration in Patients With Chronic Hepatitis B HRS-5635, Placebo - Chronic Hepatitis B | Phase 1 | Unknown | Fujian Shengdi Pharmaceutical Co., Ltd. | 85 | 2023-04-30 | 2023-06-18 |
| Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-388 in Healthy Subjects D418 Tab., CKD-388 Tab. - Chronic Hepatitis b | Phase 1 | Unknown | Chong Kun Dang Pharmaceutical | 56 | 2021-02-26 | 2020-12-21 |
| Safety, Tolerability and Pharmacokinetic Characteristics Evaluation of GST-HG131 Tablets GST-HG131 tablets, Placebo - Hepatitis B | Phase 1 | Unknown | Fujian Cosunter Pharmaceutical Co. Ltd | 124 | 2020-08-18 | 2020-09-24 |
| A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of Oral HRS5091 in Healthy Subjects and Chronic Hepatitis B Patients HRS5091 - Chronic Hepatitis B | Phase 1 | Unknown | Jiangsu HengRui Medicine Co., Ltd. | 108 | 2020-07-28 | 2021-10-22 |
| Study on the Tolerance and Pharmacokinetics of GST-HG141 Tablets GST-HG141 tablets, Placebo - Hepatitis B | Phase 1 | Unknown | Fujian Cosunter Pharmaceutical Co. Ltd | 104 | 2020-05-18 | 2020-06-04 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics of Single and Multiple Doses of Hepenofovir Fumarate Tablets in Healthy Volunteers. Hepenofovir Fumarate Tablets Single Dose, Placebo, Hepenofovir Fumarate Tablets Dose4 - Chronic Hepatitis b | Phase 1 | Unknown | Xi'an Xintong Pharmaceutical Research Co.,Ltd. | 69 | 2020-03-15 | 2020-02-20 |
| Immunotherapy of Advanced Hepatitis B Related Hepatocellular Carcinoma With γδT Cells autologous γδT cells - Hepatocellular Carcinoma | Phase 1 | Unknown | Beijing 302 Hospital | 20 | 2019-07-23 | 2019-07-25 |
| A Study to Investigate the Safety, Efficacy and PK of Multiple Doses of QL-007 in Chronic Hepatitis B Patients in CHINA QL-007 tablet, TDF - Chronic Hepatitis b | Phase 1 | Unknown | Qilu Pharmaceutical Co., Ltd. | 60 | 2018-10-16 | 2018-12-10 |
| A Study to Investigate the Safety, Efficacy and Pharmacokinetic Profile of Multiple Doses of QL-007 in Chronic Hepatitis B Patients QL-007 tablet - Chronic Hepatitis b | Phase 1 | Unknown | Qilu Pharmaceutical Co., Ltd. | 18 | 2017-08-20 | 2018-07-16 |
| A Clinical Trial on Hepatitis B Vaccine Activated-Dendritic Cells Combined With Anti-HBV Drugs in CHB HPDC-T cells & Entecavir, Entecavir, HPDC-T cells & IFN-a-2a - Chronic Hepatitis B | Phase 1 / Phase 2 | Unknown | Third Affiliated Hospital, Sun Yat-Sen University | 450 | 2015-11-01 | 2015-11-26 |
| The Treatment With HBIG+GM-CSF+HBV Vaccine for Chronic Hepatitis B Patients With HBeAg Seroconversion Drug, GM-CSF control - Chronic Hepatitis B | Phase 1 / Phase 2 | Unknown | Beijing 302 Hospital | 40 | 2013-06-01 | 2013-07-24 |
| Umbilical Cord Mesenchymal Stem Cells Transplantation Combined With Plasma Exchange for Patients With Liver Failure Conventional plus UC-MSC treatment, Conventional plus PE treatment, Conventional plus UC-MSC and PE therapy - Liver Failure | Phase 1 / Phase 2 | Unknown | Third Affiliated Hospital, Sun Yat-Sen University | 120 | 2012-11-01 | 2013-02-28 |
| Pegylated Interferon and Entecavir Combination in Chronic Hepatitis B (CHB) Pegalyted interferon, Entecavir - Chronic Hepatitis B | Phase 1 / Phase 2 | Unknown | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 20 | 2012-03-01 | 2012-05-02 |
| Dose Escalation of Interleukin-1 (IL-7) Added on Antiviral Treatment and Vaccination in HBeAg-negative Chronic Hepatitis B Virus (HBV) Infected Patients CYT107+GenHevac+entecavir or tenofovir, CYT107+ entecavir or tenofovir - Chronic Hepatitis B | Phase 1 / Phase 2 | Unknown | Cytheris SA | 24 | 2009-12-01 | 2012-10-18 |
Hepatitis B, Chronic (14) · Carcinoma, Hepatocellular (1) · Diphtheria (1) · Haemophilus Infections (1) · Hepatitis, Chronic (1) · Liver Diseases (1) · Liver Failure (1) · Poliomyelitis (1) · Tetanus (1) · Virus Diseases (1) · Whooping Cough (1)
Blood-Borne Infections (19) · Communicable Diseases (19) · DNA Virus Infections (19) · Digestive System Diseases (19) · Hepadnaviridae Infections (19) · Hepatitis (19) · Hepatitis, Viral, Human (19) · Infections (19) · Liver Diseases (18) · Virus Diseases (18) · Chronic Disease (14) · Disease Attributes (14) · Pathologic Processes (14) · Pathological Conditions, Signs and Symptoms (14)
entecavir (2) · peginterferon alfa-2a (2) · Congresses as Topic (1) · Drug and Narcotic Control (1) · GST-HG131 (1) · Pharmaceutical Preparations (1) · Population Groups (1) · Telbivudine (1) · Tenofovir (1)
Beijing 302 Hospital (3) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (2) · Fujian Cosunter Pharmaceutical Co. Ltd (2) · Qilu Pharmaceutical Co., Ltd. (2) · Third Affiliated Hospital, Sun Yat-Sen University (2) · Xi'an Xintong Pharmaceutical Research Co.,Ltd. (2) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Chong Kun Dang Pharmaceutical (1) · Cytheris SA (1) · Fujian Shengdi Pharmaceutical Co., Ltd. (1) · Jiangsu HengRui Medicine Co., Ltd. (1) · LG Chem (1)
China (12) · Bangladesh (1) · France (1) · Italy (1) · New Zealand (1) · South Korea (1)
Junqi Niu, PHD (2) · Christophe Hezode (1) · Fu-Sheng Wang, Dr (1) · Fu-Sheng Wang, M.D. (1) · Fu-Sheng Wang, MD (1) · Lubiao Chen, MD.&PHD. (1) · Mamun A Mahtab, MSc MD FACG (1) · Nam Joong Kim (1) · Pietro Andreone (1) · Zhi-Liang Gao, Doctor (1)
PMID 30863450, PMID 35404074, PMID 36089112
2009 (1)