12 completed, 12 unknown, 4 terminated, 2 withdrawn. 5 Phase 3, 3 Phase 1, 3 Phase 4, 2 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 2, Terminated 2, Unknown 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 4 | 3 | Withdrawn 2, Unknown 1 |
| Not applicable | 2 | Recruiting 1, Unknown 1 |
| Phase 2 | 2 | Terminated 2 |
Follow Heparin-induced Thrombocytopenia: new trials by email Literature Review of Heparin-induced Thrombocytopenia trials Research Report on Heparin-induced Thrombocytopenia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cangrelor As Treatment for Cardiac Surgery Associated With Heparin Induced Thrombocytopenia Heparin-induced Thrombocytopenia | Not yet recruiting | Société Française d'Anesthésie et de Réanimation | 132 | 2026-11-01 | 2026-09-14 | |
| Argatroban Monitoring in Acute Suspected Heparin-induced Thrombocytopenia. Heparin-induced Thrombocytopenia | Unknown | Assistance Publique - Hôpitaux de Paris | 200 | 2023-11-01 | 2023-10-04 | |
| Characterization and Quantification of Platelet/Leukocyte Aggregates in Patients With Suspected Heparin-induced Thrombocytopenia blood sample - Heparin-induced Thrombocytopenia, HIT | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 200 | 2023-04-17 | 2025-05-25 |
| Comparison of Pre-test Probability Model for Heparin-induced Thrombocytopenia in Post-operative Cardiac Surgery Post screening diagnostic test - Heparin-induced Thrombocytopenia | Unknown | Central Hospital, Nancy, France | 200 | 2023-03-01 | 2023-03-24 | |
| Multicenter Study on Dialysis Modalities for End-stage Chronic Renal Failure Patients With Heparin-induced Thrombocytopenia Hydrolink NV membrane - Dialysis; Complications, Heparin-induced Thrombocytopenia | Not applicable | Unknown | GCS Ramsay Santé pour l'Enseignement et la Recherche | 20 | 2022-11-20 | 2022-10-19 |
| A Phase I Study of the Co-administration of VLX-1005 and Argatroban in Healthy Human Subjects VLX-1005, Argatroban - Heparin-induced Thrombocytopenia | Phase 1 | Completed | Veralox Therapeutics | 12 | 2022-03-07 | 2023-01-11 |
| Evaluation of the Intra-observer Agreement of the HEP Score in Surgical Intensive Care. HEP score assessement - Heparin-induced Thrombocytopenia | Unknown | Centre Hospitalier Universitaire de Besancon | 124 | 2021-03-01 | 2021-03-04 | |
| PLATELET Function Assay With Flow Imaging on ImageSTREAM Cytometer Platelet Disorder, Heparin-induced Thrombocytopenia | Completed | Centre Hospitalier Universitaire, Amiens | 31 | 2021-03-01 | 2026-06-12 | |
| Argatroban Monitoring in Critically Ill Patients: Evaluation of a Novel Ecarin-based Bedside Test ECA-Test (Clot-Pro) - Heparin-induced Thrombocytopenia | Unknown | Medical University of Vienna | 21 | 2020-08-01 | 2021-02-15 | |
| Open-Label, Randomised, Active Controlled, Multi-Centre Phase 3 Study Safety and Efficacy of Danaparoid vs Argatroban Danaparoid Sodium, Argatroban - Heparin-induced Thrombocytopenia | Phase 3 | Terminated | Aspen Global Incorporated | 7 | 2019-05-16 | 2022-12-08 |
| Efficacy and Safety of Apixaban in the Treatment of Heparin Induced Thrombocytopenia (HIT) Apixaban - Heparin-induced Thrombocytopenia, Heparin-induced Thrombocytopenia and Thrombosis | Phase 2 | Terminated | Massachusetts General Hospital | 5 | 2018-12-18 | 2020-12-23 |
| Thrombotic Biomarkers to Predict Thrombosis in Heparin-induced Thrombocytopenia HIT with thrombosis - Heparin-Induced Thrombocytopenia, Thrombosis | Unknown | Wuhan Asia Heart Hospital | 200 | 2017-11-20 | 2017-08-31 | |
| Multi-Center Single Arm Trial to Determine The Effectiveness of Warfarin Therapy Duration For Heparin-Induced Thrombocytopenia (HIT) Warfarin, NOAC - Heparin-induced Thrombocytopenia | Phase 3 | Unknown | Marshall University | 70 | 2017-01-11 | 2018-08-15 |
| Pharmacogenomics of Heparin-Induced Thrombocytopenia Blood Draw - Heparin-induced Thrombocytopenia | Unknown | University of Arizona | 125 | 2016-03-01 | 2024-06-27 | |
| Prognosis Related to Induced Thrombopenia With Heparin Under Venoarterial ECMO in Reanimation Hospitalization for more than 3 days with high clinical suspicion of HIT and positive anti-PF4/heparin antibodies - Heparin-induced Thrombocytopenia | Completed | Central Hospital, Nancy, France | 39 | 2016-01-01 | 2019-06-07 | |
| Immunogenetics of Heparin-Induced Thrombocytopenia: Aim 2 Blood Draw - Heparin-induced Thrombocytopenia | Completed | Vanderbilt University Medical Center | 15 | 2015-03-01 | 2020-02-17 | |
| Rivaroxaban for Treatment of Patients With Suspected or Confirmed Heparin-Induced Thrombocytopenia Rivaroxaban - Heparin-induced Thrombocytopenia | Phase 3 | Terminated | McMaster University | 22 | 2013-01-01 | 2016-03-25 |
| Generation of Heparin-induced Thrombocytopenia (HIT)-Antibodies Without Prior Heparin Exposure Heparin-Induced Thrombocytopenia, Thrombosis | Unknown | Johann Wolfgang Goethe University Hospital | 160 | 2010-04-01 | 2010-04-15 | |
| Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients Heparin-induced Thrombocytopenia, Liver Transplantation | Completed | CHIR-Net | 39 | 2010-01-01 | 2012-08-01 | |
| Validating 4Ts for Heparin Induced Thrombocytopenia (HIT) Scoring 4Ts and Chong scale, Blood draw - Heparin-Induced Thrombocytopenia | Unknown | Medstar Health Research Institute | 500 | 2009-08-01 | 2009-07-27 |
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Thrombosis (9) · Thrombocytopenia (5) · Venous Thrombosis (2) · Acute Coronary Syndrome (1) · Blood Platelet Disorders (1) · Disease (1) · Kidney Failure, Chronic (1) · Pulmonary Embolism (1) · Thromboembolism (1) · Venous Thromboembolism (1)
Cardiovascular Diseases (11) · Embolism and Thrombosis (11) · Vascular Diseases (11) · Hematologic Diseases (6) · Hemic and Lymphatic Diseases (6) · Blood Platelet Disorders (5) · Cytopenia (5) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Chronic Disease (1) · Disease Attributes (1) · Embolism (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Heart Diseases (1)
Blood Specimen Collection (5) · argatroban (4) · Fondaparinux (3) · Warfarin (2) · bivalirudin (2) · Blood Coagulation (1) · Heparin, Low-Molecular-Weight (1) · Hospitalization (1) · N(4)-oleylcytosine arabinoside (1) · Rivaroxaban (1) · apixaban (1) · danaparoid (1) · lepirudin (1)
Central Hospital, Nancy, France (2) · Centre Hospitalier Universitaire, Amiens (2) · McMaster University (2) · Ministry of Health, Labour and Welfare, Japan (2) · The Medicines Company (2) · Aspen Global Incorporated (1) · Assistance Publique - Hôpitaux de Paris (1) · Brigham and Women's Hospital (1) · CHIR-Net (1) · Centre Hospitalier Universitaire de Besancon (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Children's Hospital Los Angeles (1) · GCS Ramsay Santé pour l'Enseignement et la Recherche (1) · Johann Wolfgang Goethe University Hospital (1) · Marshall University (1)
United States (13) · France (8) · Germany (4) · Canada (3) · Japan (2) · Austria (1) · Bosnia and Herzegovina (1) · Italy (1) · Poland (1) · Russia (1) · Serbia (1)
Allen Hunt, MBA (1) · Andreas Greinacher, Prof. Dr. (1) · Andrew F Shorr, MD, MPH (1) · Bob L Lobo, Pharm.D. (1) · Chee M Chan, MD (1) · Edelgard Lindhoff-Last, Prof. (1) · Elizabeth Phillips Phillips, MD (1) · Goetz H Kloecker, MD, MSPH (1) · Guillaume Besch, MD (1) · Guy Young, MD (1) · Lori-Ann Linkins, MD (1) · Lori-Ann Linkins, MD, MSc (1) · Magnus Ohman, MD (1)
PMID 20854372, PMID 21319285, PMID 25611568, PMID 25926600, PMID 33872452