4 completed, 1 not yet recruiting, 1 unknown. 6 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 4, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Hemoglobin SC Disease: new trials by email Literature Review of Hemoglobin SC Disease trials Research Report on Hemoglobin SC Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Buprenorphine for the Management of Pain in Children With Sickle Cell Disease Buprenorphine Buccal Film [Belbuca] - Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis | Phase 1 | Not yet recruiting | Natasha Archer | 25 | 2026-10-01 | 2026-09-02 |
| Pharmacokinetics of Oral Hydroxyurea Solution Oral Hydroxyurea (100 mg/mL) Solution - Sickle Cell Disease, Sickle-Cell; Hemoglobin Disease, Thalassemia | Phase 1 / Phase 2 | Completed | Nova Laboratories Limited | 33 | 2019-01-03 | 2024-10-28 |
| A Study of IMR-687 in Healthy Adult Volunteers IMR-687, Placebo Oral Capsule - Sickle Cell Disease, Sickle-Cell; Hb-SC | Phase 1 | Completed | Cardurion Pharmaceuticals, Inc. | 66 | 2016-10-18 | 2025-05-15 |
| Safety Study of MP4CO in Adult Sickle Cell Patients MP4CO, Sodium chloride solution - Anemia, Sickle Cell, Sickle Cell Anemia | Phase 1 | Completed | Sangart | 32 | 2012-01-01 | 2013-08-19 |
| Far Infrared Radiation for Sickle Cell Pain Management Far Infrared Radiation (5μm to 20μm wavelength) - Anemia, Sickle Cell | Phase 1 | Unknown | GAAD Medical Research Institute Inc. | 10 | 2008-01-01 | 2009-01-05 |
| A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders Recombinant-methionyl human stem cell factor - Hemoglobin SC Disease, Sickle Cell Anemia | Phase 1 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 50 | 2000-03-01 | 2008-03-04 |
Anemia, Sickle Cell (6) · Vaso-Occlusive Crises (3) · Thalassemia (2) · Acute Pain (1) · Hemoglobin C Disease (1) · Hemoglobinopathies (1) · Sickle Cell Trait (1) · beta-Thalassemia (1)
Anemia (6) · Anemia, Hemolytic (6) · Anemia, Hemolytic, Congenital (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Hematologic Diseases (6) · Hemic and Lymphatic Diseases (6) · Hemoglobinopathies (5) · Neurologic Manifestations (1) · Pain (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1) · Thalassemia (1)
Buprenorphine (1) · Hydroxyurea (1) · PEGylated carboxyhemoglobin bovine (1) · Saline Solution (1) · Sodium Chloride (1) · Solutions (1) · ancestim (1) · microcrystalline cellulose (1)
Cardurion Pharmaceuticals, Inc. (1) · GAAD Medical Research Institute Inc. (1) · Natasha Archer (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1) · Nova Laboratories Limited (1) · Sangart (1)
United States (3) · Jamaica (2) · United Kingdom (2) · Canada (1) · France (1) · Lebanon (1)
Angela E Rankine- Mullings, MD (1) · Ken Nedd, M.D. (1) · Kwasi Donyina, Ph.D. (1) · Natasha Archer, MD (1) · Regulatory Operations (1) · Tania Small, MD (1)
2017 (1)