1 completed, 1 enrolling by invitation, 1 recruiting, 1 unknown. 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow GNAO1: new trials by email Literature Review of GNAO1 trials Research Report on GNAO1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. Antisense oligonucleotide treatment (ASO) - GNAO1, Epilepsy | Phase 1 / Phase 2 | Recruiting | Pirogov Russian National Research Medical University | 5 | 2025-09-09 | 2026-01-23 |
| Deep Brain Stimulation (DBS) MatchMaker TOR1A, PANK2 | Enrolling by invitation | Boston Children's Hospital | 500 | 2024-12-01 | 2026-04-13 | |
| Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders Zinc Acetate Dihydrate - GNAO1, Dystonia | Phase 2 | Completed | Children's University Hospital Cologne, Germany | 13 | 2024-08-02 | 2026-02-03 |
| GNAO1 Natural History Study GNAO1 | Unknown | Washington University School of Medicine | 50 | 2019-02-18 | 2021-07-06 |
Epilepsy (3) · Dystonia (2) · Movement Disorders (2) · Chorea (1) · Hyperkinesis (1) · Learning Disabilities (1)
Central Nervous System Diseases (4) · Nervous System Diseases (4) · Brain Diseases (3) · Dyskinesias (3) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Communication Disorders (1) · Mental Disorders (1) · Neurobehavioral Manifestations (1) · Neurodevelopmental Disorders (1)
Zinc Acetate (1)
Boston Children's Hospital (1) · Children's University Hospital Cologne, Germany (1) · Pirogov Russian National Research Medical University (1) · Washington University School of Medicine (1)
United States (2) · Germany (1) · Russia (1)
Amy Viehoever, MD, Ph.D. (1) · Elena D Belousova, Prof (1) · Moritz Thiel, MD (1)