1 completed, 1 recruiting. 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow GNAO1: new trials by email Literature Review of GNAO1 trials Research Report on GNAO1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. Antisense oligonucleotide treatment (ASO) - GNAO1, Epilepsy | Phase 1 / Phase 2 | Recruiting | Pirogov Russian National Research Medical University | 5 | 2025-09-09 | 2026-01-23 |
| Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders Zinc Acetate Dihydrate - GNAO1, Dystonia | Phase 2 | Completed | Children's University Hospital Cologne, Germany | 13 | 2024-08-02 | 2026-02-03 |
Epilepsy (2) · Dystonia (1) · Hyperkinesis (1) · Learning Disabilities (1)
Brain Diseases (2) · Central Nervous System Diseases (2) · Dyskinesias (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Communication Disorders (1) · Mental Disorders (1) · Neurobehavioral Manifestations (1) · Neurodevelopmental Disorders (1)
Zinc Acetate (1)
Children's University Hospital Cologne, Germany (1) · Pirogov Russian National Research Medical University (1)
Germany (1) · Russia (1)
Elena D Belousova, Prof (1) · Moritz Thiel, MD (1)