4 completed, 2 unknown, 1 active not recruiting, 1 recruiting. 3 Phase 2, 1 Early Phase 1, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Early Phase 1 | 1 | Completed 1 |
| Not applicable | 1 | Suspended 1 |
| Phase 1 | 1 | Completed 1 |
Follow GLUT1DS1: new trials by email Literature Review of GLUT1DS1 trials Research Report on GLUT1DS1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Red Blood Cell Exchange Transfusion as a Novel Treatment for GLUT1 Deficiency Syndrome Red Blood Cell Transfusion - Glucose Transporter Type 1 Deficiency Syndrome, GLUT1DS1 | Not applicable | Suspended | Weill Medical College of Cornell University | 12 | 2027-09-01 | 2025-12-11 |
| A Phase II Study With Exploratory Outcomes of Fucose Supplementation in GLUT1 Deficiency Syndrome L-fucose, Placebo - Glut1 Deficiency, GLUT1DS1 | Phase 2 | Recruiting | Oregon Health and Science University | 16 | 2026-05-05 | 2026-05-13 |
| Harmonic Ratio in Patients With GLUT1 Deficiency Syndrome Inertial gait analysis - GLUT1DS1, Dystonia | Active not recruiting | IRCCS National Neurological Institute "C. Mondino" Foundation | 32 | 2023-01-01 | 2024-04-30 | |
| Sodium Lactate Infusion in GLUT1DS Patients sodiumlactate - GLUT1 Deficiency Syndrome, GLUT1DS1 | Early Phase 1 | Completed | Radboud University Medical Center | 2 | 2022-05-20 | 2022-11-23 |
| Ketonemia Through Menstrual Cycle Evaluation of ketogenic diet impact on ketonemia - Epilepsy, Drug Resistant Epilepsy | Unknown | University of Pavia | 15 | 2020-07-01 | 2023-05-11 | |
| Long-term Treatment With the Ketogenic Diet in Epilepsy Color duplex ultrasound of the carotid arteries - Epilepsy, GLUT1DS1 | Unknown | Oslo University Hospital | 30 | 2018-08-06 | 2022-10-21 | |
| Compatibility of C7 With Ketogenic Diet in Patients Diagnosed With G1D Triheptanoin - GLUT1DS1 | Phase 2 | Completed | University of Texas Southwestern Medical Center | 10 | 2018-06-05 | 2024-01-17 |
| Diet Treatment Glucose Transporter Type 1 Deficiency (G1D) Triheptanoin - GLUT1DS1, Epilepsy | Phase 2 | Completed | University of Texas Southwestern Medical Center | 45 | 2018-04-18 | 2025-08-07 |
| Treatment Development of Triheptanoin (G1D) Triheptanoin - Epilepsy, GLUT1DS1 | Phase 1 | Completed | Juan Pascual | 12 | 2017-03-29 | 2022-12-22 |
Epilepsy (5) · Glut1 Deficiency Syndrome (5) · Glucose Metabolism Disorders (2) · Glycogen Storage Disease Id (2) · Drug Resistant Epilepsy (1) · Dystonia (1) · Dystonia 18 (1) · Gait Ataxia (1) · Gait Disorders, Neurologic (1) · Hyperlactatemia (1) · Ketosis (1) · Pyruvate Dehydrogenase Complex Deficiency Disease (1)
Nervous System Diseases (6) · Brain Diseases (5) · Central Nervous System Diseases (5) · Metabolic Diseases (5) · Nutritional and Metabolic Diseases (5) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Acid-Base Imbalance (1) · Acidosis (1) · Ataxia (1) · Brain Diseases, Metabolic (1) · Brain Diseases, Metabolic, Inborn (1) · Carbohydrate Metabolism, Inborn Errors (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1)
triheptanoin (3) · Erythrocyte Transfusion (1) · Fucose (1)
University of Texas Southwestern Medical Center (2) · IRCCS National Neurological Institute "C. Mondino" Foundation (1) · Juan Pascual (1) · Oregon Health and Science University (1) · Oslo University Hospital (1) · Radboud University Medical Center (1) · University of Pavia (1) · Weill Medical College of Cornell University (1)
United States (5) · Italy (2) · Netherlands (1) · Norway (1)
Anette Ramm-Pettersen, MD PhD (1) · Juan Pascual (1) · Juan Pascual, M.D. (1) · Juan Pascual, MD (1) · Juan Pascual, MD, PhD (1) · Roberto De Icco (1) · Rodrigo T. Starosta, MD, PhD (1) · Valentina De Giorgis (1)
PMID 36523131, PMID 36859467, PMID 37268656, PMID 37575326
R01NS094257 (3), RM1NS133593 (1)