18 recruiting, 14 completed, 14 unknown, 8 active not recruiting. 24 Phase 1, 16 Not applicable, 11 Phase 2, 7 Early Phase 1, 1 Phase 3.
Follow Glioma, Malignant: new trials by email Literature Review of Glioma, Malignant trials Research Report on Glioma, Malignant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG 18F-Fluciclovine - Glioma, Low-grade Glioma | Early Phase 1 | Recruiting | Children's Hospital of Philadelphia | 30 | 2026-11-29 | 2026-09-22 |
| Phase II Elderly/Frail Pts With Newly Diagnosed or Recurrent Malignant Glioma Treated With Cesium-131 GammaTile® GammaTile® - Glioma, Glioblastoma | Phase 2 | Not yet recruiting | University of California, Irvine | 20 | 2026-10-01 | 2026-09-23 |
| Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma LMP744, Conventional Surgery or Biopsy - Recurrent Glioblastoma, Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype | Phase 1 / Phase 2 | Recruiting | National Institute of Neurological Disorders and Stroke (NINDS) | 40 | 2026-07-15 | 2026-10-16 |
| Nimotuzumab Combined With the Stupp Regimen for Postoperative Residual Glioblastoma nimotuzumab, Temozolomide, Radiotherapy - Glioma, Malignant | Phase 2 | Not yet recruiting | Tianjin First Central Hospital | 50 | 2026-07-03 | 2026-07-16 |
| A Phase I/IIa Study of C5252 in Patients With Intracranial Tumor Herpes Virus C5252 Injection - Glioma, Malignant | Phase 1 / Phase 2 | Recruiting | ImmVira Pharma Co. Ltd | 36 | 2026-04-03 | 2026-08-17 |
| CUE-102 in Recurrent Glioblastoma CUE-102 - Recurrent Glioblastoma, Glioblastoma | Phase 1 | Recruiting | David Reardon, MD | 18 | 2025-07-30 | 2026-03-05 |
| Imaging of Solid Tumors Using 18F-TRX 18F-TRX, Positron Emission Tomography (PET)/Computerized tomography (CT), Tumor Biopsy - Solid Tumor, Solid Carcinoma | Phase 1 | Recruiting | Rahul Aggarwal | 56 | 2025-07-03 | 2026-07-23 |
| Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma NSC-CRAd-S-pk7 - Glioma, Malignant, New Diagnosis Tumor | Phase 1 | Active not recruiting | Northwestern University | 20 | 2025-06-27 | 2026-10-16 |
| Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and Gliomas Tissue, blood, cerebrospinal-spinal fluid - Glioma, Malignant, Embryonal Tumor | Not yet recruiting | University Hospital Regensburg | 72 | 2025-05-01 | 2025-03-25 | |
| PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial PRDR - Glioma, Glioma, Malignant | Not applicable | Recruiting | Baptist Health South Florida | 28 | 2025-04-30 | 2026-06-01 |
| Window of Opportunity Study of DSP-0390 in Gliomas DSP-0390 - Glioma, Malignant, IDH Mutation | Early Phase 1 | Recruiting | Washington University School of Medicine | 20 | 2025-04-03 | 2026-05-06 |
| Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss TNG456, abemaciclib - Non Small Cell Lung Cancer, Glioma Glioblastoma Multiforme | Phase 1 / Phase 2 | Recruiting | Tango Therapeutics, Inc. | 191 | 2025-03-24 | 2026-10-21 |
| Niraparib and Temozolomide in Patients Glioblastoma Temodal, Niraparib - Glioma, Malignant | Phase 1 / Phase 2 | Not yet recruiting | Armando Santoro, MD | 86 | 2024-09-01 | 2024-08-30 |
| In Vitro Models From Pediatric Brain Tumors other - Glioma, Malignant, Ependymoma | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 100 | 2024-09-01 | 2024-07-12 | |
| Clinical Study on the Safety and Efficacy of TS-2021 in the Treatment of Recurrent Malignant Glioma TS-2021 - Glioblastoma Multiforme, Glioma, Malignant | Phase 1 | Unknown | Beijing Neurosurgical Institute | 30 | 2024-08-29 | 2024-10-31 |
| 18F-Fluciclovine PET-MRI in High-grade Glioma 18F-Fluciclovine PET-MRI - Glioma, High Grade Glioma | Early Phase 1 | Recruiting | Children's Hospital of Philadelphia | 30 | 2024-08-07 | 2025-12-04 |
| Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma Cognitive Behavioral Therapy (CBT) neuropsychologist - Glioma, Malignant | Not applicable | Recruiting | Institut du Cancer de Montpellier - Val d'Aurelle | 187 | 2024-07-05 | 2025-12-19 |
| Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life Resting State Functional Magnetic Resonance Imaging (rs-fMRI), Up-front Motor Rehabilitation, Up-front Chemotherapy - Glioma, Glioma, Malignant | Not applicable | Recruiting | University of Milan | 400 | 2024-03-07 | 2024-04-24 |
| Monitoring of Patients With Diffuse Gliomas Using Circulating miRNAs Blood sample - Glioma, Malignant | Recruiting | University Hospital, Caen | 60 | 2024-01-01 | 2024-01-12 | |
| FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma FET PET - Glioma, Malignant | Phase 2 | Recruiting | Singapore General Hospital | 22 | 2023-12-21 | 2024-12-03 |
Showing 20 of 72. Sign in to see all of them.
Glioma (72) · Glioblastoma (31) · Brain Neoplasms (12) · Neoplasms (6) · Astrocytoma (4) · Ependymoma (4) · Oligodendroglioma (4) · Central Nervous System Neoplasms (3) · Medulloblastoma (3) · Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Diffuse Intrinsic Pontine Glioma (2) · Neoplasms, Germ Cell and Embryonal (2) · Neoplasms, Neuroepithelial (2) · Prostatic Neoplasms (2)
Neoplasms, Glandular and Epithelial (72) · Neoplasms by Histologic Type (71) · Neoplasms, Nerve Tissue (71) · Neuroectodermal Tumors (71) · Neoplasms, Germ Cell and Embryonal (70) · Neoplasms, Neuroepithelial (70) · Neoplasms (66) · Astrocytoma (28) · Neoplasms by Site (16) · Nervous System Diseases (16) · Central Nervous System Diseases (15) · Brain Diseases (14) · Nervous System Neoplasms (14) · Central Nervous System Neoplasms (11) · Pathological Conditions, Signs and Symptoms (6)
Temozolomide (6) · Radiotherapy (4) · Blood Specimen Collection (3) · Radiation (3) · niraparib (3) · Biopsy (2) · Granulocyte-Macrophage Colony-Stimulating Factor (2) · fluciclovine F-18 (2) · poly ICLC (2) · AZD1390 (1) · Aminolevulinic Acid (1) · Bevacizumab (1) · Cognitive Behavioral Therapy (1) · Cyclophosphamide (1) · D2C7-(scdsFv)-PE38KDEL (1)
Northwell Health (4) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (3) · Nader Sanai (3) · Children's Hospital of Philadelphia (2) · Genetron Health (2) · Jinsong Wu (2) · Mingge LLC (2) · Sklifosovsky Institute of Emergency Care (2) · Washington University School of Medicine (2) · Aminex Therapeutics, Inc. (1) · Armando Santoro, MD (1) · Assiut University (1) · Baptist Health South Florida (1) · Beijing Neurosurgical Institute (1) · Beijing Tiantan Hospital (1)
United States (31) · China (12) · Italy (8) · France (2) · Russia (2) · Spain (2) · United Kingdom (2) · Australia (1) · Bosnia and Herzegovina (1) · Bulgaria (1) · Canada (1) · Ecuador (1) · Egypt (1) · Finland (1) · Georgia (1)
John Boockvar, MD (4) · Nader Sanai, MD (3) · Alexander Dmitriev, MD (2) · Jinhua Yu, DE (2) · Mariam Aboian, MD,PhD (2) · Mustafa Khasraw, MBChB, MD, FRCP, FRACP (2) · Zhifeng Shi, DM (2) · Adam Crystal, MD, PhD (1) · Ahmed AlGhriany, phD (1) · Ahmed AlShanawany, phD (1) · Alberto Valarezo Chuchuca, MD (1) · Allen Mellemed, MD (1) · Amit Singnurkar, MD, MBA (1) · Annick Desjardins, MD,FRCPC (1)
PMID 40457320, PMID 2827051, PMID 34025640, PMID 35137228, PMID 35906549, PMID 36753564, PMID 38041959, PMID 38049523, PMID 38335473, PMID 38413458, PMID 39499201, PMID 39747932, PMID 40120123, PMID 41064168, PMID 42875659
P01CA225622 (1), P50CA165962 (1), P50CA190991 (1), UM1CA137443 (1)