427 completed. 427 Phase 2, 131 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 427 | Completed 427 |
| Phase 1 | 131 | Completed 131 |
| Phase 3 | 1 | Completed 1 |
Follow Glioblastoma: new trials by email Literature Review of Glioblastoma trials Research Report on Glioblastoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial Cognitive Behavioral Therapy for Insomnia - Primary Brain Tumor, Glioblastoma | Phase 2 | Completed | Virginia Commonwealth University | 70 | 2024-07-08 | 2025-10-01 |
| Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma Azeliragon 5 mg, Azeliragon 10 mg, Azeliragon 20 mg - Glioblastoma | Phase 1 / Phase 2 | Completed | Cantex Pharmaceuticals | 33 | 2023-09-05 | 2026-10-19 |
| TN-TC11G (THC+CBD) Combination With Temozolomide and Radiotherapy in Patients With Newly-diagnosed Glioblastoma TN-TC11G, Temozolomide Oral Product, Radiotherapy - Glioblastoma | Phase 1 / Phase 2 | Completed | Grupo Español de Investigación en Neurooncología | 33 | 2023-08-18 | 2026-02-12 |
| Sonodynamic Therapy With ExAblate System in Glioblastoma Patients 5-Aminolevulinic Acid - Glioblastoma Multiforme | Phase 2 | Completed | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 5 | 2023-02-22 | 2024-11-12 |
| Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma Paxalisib, Metformin, Ketogenic Diet - Glioblastoma | Phase 2 | Completed | Weill Medical College of Cornell University | 24 | 2022-02-14 | 2026-09-25 |
| Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma TMZ, ipilimumab 3mg/kg, Nivolumab - Glioblastoma, Gliosarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 47 | 2021-12-08 | 2026-04-17 |
| Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System tozuleristide, Canvas imaging system, Surgical resection of tumor - Central Nervous System Tumor | Phase 2 | Completed | John Yu | 50 | 2021-09-30 | 2026-07-10 |
| Dose Finding for Intraoperative Photodynamic Therapy of Glioblastoma Gliolan, Intraoperative PDT - Glioblastoma | Phase 2 | Completed | University Hospital, Lille | 14 | 2021-09-28 | 2025-12-05 |
| A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors Regorafenib, (Stivarga, BAY73-4506), Nivolumab (Opdivo) - Solid Tumors | Phase 2 | Completed | Bayer | 175 | 2021-02-03 | 2025-04-18 |
| Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd Talazoparib - Recurrent Glioma, Recurrent Glioblastoma | Phase 2 | Completed | The University of Hong Kong | 33 | 2021-01-01 | 2025-06-11 |
| 11C-methionine in Diagnostics and Management of Glioblastoma Multiforme Patients (GlioMET) 11C-Methionine PET/CT - Glioblastoma Multiforme | Phase 2 | Completed | Masaryk Memorial Cancer Institute | 33 | 2020-12-04 | 2025-09-25 |
| A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma Abemaciclib, Irinotecan, Temozolomide - Relapsed Solid Tumor, Refractory Solid Tumor | Phase 1 / Phase 2 | Completed | Eli Lilly and Company | 47 | 2020-11-09 | 2026-03-02 |
| Exablate Blood-Brain Barrier Disruption for the Treatment of rGBM in Subjects Undergoing Carboplatin Monotherapy Carboplatin, Exablate BBBD - Recurrent Glioblastoma | Phase 1 / Phase 2 | Completed | InSightec | 28 | 2020-11-06 | 2026-03-20 |
| LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastoma lerapolturev, pembrolizumab - Glioblastoma, Recurrent Glioblastoma | Phase 2 | Completed | Istari Oncology, Inc. | 25 | 2020-10-21 | 2025-06-05 |
| Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM Exablate BBBD, Carboplatin - Recurrent Glioblastoma | Phase 1 / Phase 2 | Completed | InSightec | 13 | 2020-10-13 | 2026-01-20 |
| Evaluation of GLR2007 for Advanced Solid Tumors GLR2007 - Non-small Cell Lung Cancer, Glioblastoma Multiforme | Phase 1 / Phase 2 | Completed | Gan and Lee Pharmaceuticals, USA | 19 | 2020-07-15 | 2022-12-23 |
| Open-Label Pilot Study of OPTUNE® With High Density Transducer Arrays for the Treatment of Recurrent GBM TTFields - Glioblastoma Multiforme | Phase 2 | Completed | NovoCure GmbH | 25 | 2020-07-14 | 2024-08-16 |
| First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma Multiple dose of EO2401 - Glioblastoma, Adult | Phase 1 / Phase 2 | Completed | Enterome | 100 | 2020-07-13 | 2025-11-28 |
| Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients MSC11FCD - Glioblastoma, Adult Gliosarcoma | Phase 1 / Phase 2 | Completed | CHA University | 10 | 2020-06-24 | 2023-01-18 |
| Anticancer Therapeutic Vaccination Using Telomerase-derived Universal Cancer Peptides in Glioblastoma UCPVax, Temozolomide - Glioblastoma | Phase 2 | Completed | Centre Hospitalier Universitaire de Besancon | 67 | 2020-05-26 | 2025-01-09 |
Showing 20 of 427. Sign in to see all of them.
Brain Neoplasms (187) · Gliosarcoma (187) · Glioma (133) · Central Nervous System Neoplasms (108) · Astrocytoma (106) · Oligodendroglioma (65) · Ependymoma (16) · Medulloblastoma (14) · Recurrence (13) · Glioma, Subependymal (12) · Meningioma (12) · Neoplasms (12) · Neuroectodermal Tumors, Primitive (9) · Familial ependymoma (6)
Neoplasms, Glandular and Epithelial (427) · Neoplasms by Histologic Type (426) · Neoplasms, Nerve Tissue (426) · Neuroectodermal Tumors (425) · Neoplasms, Germ Cell and Embryonal (424) · Neoplasms, Neuroepithelial (424) · Neoplasms (415) · Astrocytoma (321) · Glioma (294) · Neoplasms by Site (238) · Nervous System Diseases (226) · Nervous System Neoplasms (226) · Central Nervous System Diseases (191) · Brain Diseases (190) · Central Nervous System Neoplasms (121)
Temozolomide (115) · Bevacizumab (69) · Radiotherapy (66) · Irinotecan (18) · Radiation (16) · Erlotinib Hydrochloride (15) · Carmustine (13) · Carboplatin (12) · Surgical Procedures, Operative (12) · Lomustine (11) · Magnetic Resonance Spectroscopy (10) · temsirolimus (9) · Chemotherapy, Adjuvant (8) · Sorafenib (8) · pembrolizumab (8)
National Cancer Institute (NCI) (47) · Duke University (26) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (17) · European Organisation for Research and Treatment of Cancer - EORTC (9) · M.D. Anderson Cancer Center (9) · New Approaches to Brain Tumor Therapy Consortium (8) · Dana-Farber Cancer Institute (7) · Jonsson Comprehensive Cancer Center (7) · Memorial Sloan Kettering Cancer Center (7) · Radiation Therapy Oncology Group (7) · Alliance for Clinical Trials in Oncology (6) · Eli Lilly and Company (6) · Grupo Español de Investigación en Neurooncología (6) · Burzynski Research Institute (5) · Hoffmann-La Roche (5)
United States (310) · France (32) · Germany (27) · Spain (26) · Canada (24) · Italy (23) · Switzerland (21) · Belgium (17) · United Kingdom (17) · Netherlands (14) · Australia (10) · Austria (10) · South Korea (9) · Israel (7) · China (6)
David A. Reardon, MD (7) · Annick Desjardins, MD, FRCPC (5) · David Peereboom, MD (5) · Evanthia Galanis (5) · Stanislaw R. Burzynski, MD, PhD (5) · David Reardon, MD (4) · Katherine B Peters, MD, PhD (4) · Patrick Y. Wen, MD (4) · Darell D. Bigner, MD, PhD (3) · Edward G. Shaw, MD (3) · Evanthia Galanis, MD (3) · Henry S. Friedman, MD (3)
PMID 25098701, PMID 25113840, PMID 27580889, PMID 37540556, PMID 11772431, PMID 12749708, PMID 14670747, PMID 14769135, PMID 14769136, PMID 14769138, PMID 15073861, PMID 15292713, PMID 15758009, PMID 16012795, PMID 16034522, PMID 16053699, PMID 16133802, PMID 16170172, PMID 16443947, PMID 16549835, PMID 16750317, PMID 16817692, PMID 16877733, PMID 16914578, PMID 17031561, PMID 17317837, PMID 17470857, PMID 17882417, PMID 18094423, PMID 18182667, PMID 18215105, PMID 18403492, PMID 18661102, PMID 18723297, PMID 18775433, PMID 18824712, PMID 18955445, PMID 18981004, PMID 18981465, PMID 19075262, PMID 19188181, PMID 19204207, PMID 19269895, PMID 19381446, PMID 19533025, PMID 19562254, PMID 19720927, PMID 19725960, PMID 19816190, PMID 19854090
U01CA062475 (12), U10CA025224 (10), U10CA021661 (7), U01CA062399 (6), 2014 (4), U01CA137443 (4), 2009 (3), P30CA006516 (3), U10CA180821 (3), U10CA180868 (3), 2008 (2), 2015 (2), 2016 (2), 2017 (2), 2019 (2)