3 completed, 3 not yet recruiting, 2 active not recruiting, 1 recruiting. 3 Phase 2, 2 Phase 1, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Not yet recruiting 1 |
| Phase 1 | 2 | Not yet recruiting 1, Recruiting 1 |
| Early Phase 1 | 1 | Not yet recruiting 1 |
Follow Germ Cell Cancer: new trials by email Literature Review of Germ Cell Cancer trials Research Report on Germ Cell Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 1/2 Study Of PARP Inhibition With Olaparib To Enhance The Efficacy Of High-Dose Chemotherapy In Refractory And Relapsed Germ Cell Tumors Olaparib, Gemcitabine, Docetaxel - Germ Cell Cancer | Phase 1 / Phase 2 | Not yet recruiting | M.D. Anderson Cancer Center | 36 | 2027-03-01 | 2026-10-01 |
| A Simplified Regimen to Prevent Nausea and Vomiting Using Netupitant/Palonosetron in Germ Cell Cancer Patients Receiving Chemotherapy Netupitant/Palonosetron Hydrochloride, Ondansetron (Control), Aprepitant - Germ Cell Cancer | Early Phase 1 | Not yet recruiting | Ottawa Hospital Research Institute | 10 | 2026-08-01 | 2026-06-23 |
| YASU Research Registry: For Young Adults With Cancer Cancer, Leukemia | Terminated | Young Adult Survivors United | 192 | 2025-02-03 | 2025-10-14 | |
| SerUm and Plasma MicroRNAs in Malignant Ovarian gERm Cell Tumours Blood test, Pathology specimen miRNA expression - Germ Cell Ovarian Cancer, Germ Cell Tumor | Not yet recruiting | Imperial College London | 24 | 2024-04-14 | 2024-03-26 | |
| B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) Fludarabine, Cyclophosphamide, MESNA - Pediatric Solid Tumor, Osteosarcoma | Phase 1 | Recruiting | St. Jude Children's Research Hospital | 48 | 2022-07-06 | 2026-05-19 |
| Toxicity Attributed to Genetic Polymorphisms in Testicular Germ Cell Tumor Survivors Germ Cell Cancer | Completed | Copenhagen University Hospital, Rigshospitalet | 430 | 2014-08-01 | 2023-11-21 | |
| Brentuximab Vedotin (SGN-35) as Salvage Treatment for CD30-positive Germ Cell Tumors Brentuximab Vedotin - Germ Cell Cancer | Phase 2 | Completed | Fondazione Michelangelo | 9 | 2013-05-01 | 2018-02-07 |
| Acute Changes in Endothelial Function in Germ Cell Tumor Patients Treated With Cisplatin and Untreated Germ Cell Tumor Controls Endo-PAT2000 testing - Germ Cell Cancer | Active not recruiting | Memorial Sloan Kettering Cancer Center | 44 | 2011-10-11 | 2025-11-10 | |
| Everolimus for Patients With Relapsed/Refractory Germ Cell Cancer Everolimus - Testicular Cancer, Germ Cell Cancer | Phase 2 | Completed | Hannover Medical School | 25 | 2010-11-01 | 2015-02-25 |
| Genomic Structural Variation in Cancer Susceptibility Breast Cancer, Colon Cancer | Active not recruiting | Memorial Sloan Kettering Cancer Center | 1275 | 2009-10-01 | 2025-11-04 |
Neoplasms, Germ Cell and Embryonal (10) · Sarcoma (3) · Breast Neoplasms (2) · Melanoma (2) · Neuroblastoma (2) · Testicular Neoplasms (2) · Adrenal Cortex Neoplasms (1) · Carcinoma (1) · Carcinoma, Embryonal (1) · Cardiovascular Diseases (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Desmoplastic Small Round Cell Tumor (1) · Hepatoblastoma (1) · Leukemia (1)
Neoplasms by Histologic Type (10) · Neoplasms (9) · Neoplasms by Site (6) · Urogenital Diseases (5) · Endocrine Gland Neoplasms (4) · Endocrine System Diseases (4) · Male Urogenital Diseases (4) · Urogenital Neoplasms (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genital Diseases (3) · Gonadal Disorders (3) · Neoplasms, Connective and Soft Tissue (3) · Neoplasms, Nerve Tissue (3) · Neuroectodermal Tumors (3)
Aprepitant (1) · Brentuximab Vedotin (1) · Carboplatin (1) · Cyclophosphamide (1) · Dexamethasone (1) · Docetaxel (1) · Etoposide (1) · Everolimus (1) · Gemcitabine (1) · Hematologic Tests (1) · Mesna (1) · Olanzapine (1) · Ondansetron (1) · Palonosetron (1) · etoposide phosphate (1)
Memorial Sloan Kettering Cancer Center (2) · Copenhagen University Hospital, Rigshospitalet (1) · Fondazione Michelangelo (1) · Hannover Medical School (1) · Imperial College London (1) · M.D. Anderson Cancer Center (1) · Ottawa Hospital Research Institute (1) · St. Jude Children's Research Hospital (1) · Young Adult Survivors United (1)
United States (5) · Canada (1) · Denmark (1) · Germany (1) · Italy (1)
Alessandro M Gianni, MD (1) · Andrea Necchi, MD (1) · Chris DeRenzo, MD (1) · Darren Feldman, MD (1) · Gedske Daugaard, MD DMSc (1) · Martin H Fenner, MD (1) · Roberto Salvioni, MD (1) · Srdjan Saso, PhD MRCOG MRCS (1) · Yago Nieto, MD, PHD (1) · Zsofia Stadler, MD (1)
2009 (1)