4 recruiting, 3 unknown, 1 active not recruiting, 1 completed. 3 Not applicable, 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Unknown 2, Not yet recruiting 1 |
| Phase 2 | 3 | Active not recruiting 1, Completed 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow FSHD: new trials by email Literature Review of FSHD trials Research Report on FSHD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD Apitegromab, Placebo - Facioscapulohumeral Muscular Dystrophy, FSHD | Phase 2 | Recruiting | Scholar Rock, Inc. | 60 | 2026-07-30 | 2026-09-02 |
| A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD AOC-1020, Placebo - Facioscapulohumeral Muscular Dystrophy, FSHD | Phase 3 | Recruiting | Avidity Biosciences, Inc. | 200 | 2025-06-10 | 2026-07-27 |
| Testing a Tailored Home Exercise Program to Reduce Pain and Fatigue in Patients with FSHD. Personalised Exercise, Historical control group - FSHD | Not applicable | Not yet recruiting | Radboud University Medical Center | 50 | 2025-02-01 | 2024-12-02 |
| BetterLife FSHD: A Patient-driven Health and Research Platform Observational - FSH, FSH Muscular Dystrophy | Recruiting | FSHD Society | 5000 | 2024-08-02 | 2026-02-20 | |
| Phase 2 Open-label Extension Study of AOC 1020 in Participants With Facioscapulohumeral Muscular Dystrophy (FSHD) AOC 1020 - FSHD, FSHD1 | Phase 2 | Active not recruiting | Avidity Biosciences, Inc. | 84 | 2024-07-25 | 2026-07-14 |
| New Biomarkers in Facioscapulohumeral Muscular Dystrophy, Multispectral Optoacoustic Tomography. MSOT Acuity Echo - FSHD | Not applicable | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 20 | 2023-06-26 | 2023-07-06 |
| Phase 1/2 Study of AOC 1020 in Participants With Facioscapulohumeral Muscular Dystrophy (FSHD) AOC 1020, Placebo - FSHD, FSHD1 | Phase 1 / Phase 2 | Completed | Avidity Biosciences, Inc. | 90 | 2023-04-04 | 2026-07-16 |
| Schulze Muscular Dystrophy Ability Clinical Study Abilitech Assist - Muscular Dystrophies, Spinal Muscular Atrophy | Not applicable | Unknown | AbiliTech Medical Inc. | 35 | 2022-05-26 | 2022-12-05 |
| Pompe & Pain - Study to Assess Nociceptive Pain in Adult Patients With Pompe Disease Beck depression inventory fast screen (Questionnaire), Brief Pain Inventory (BPI) (Questionnaire), German Pain Inventory (Questionnaire) - Pompe Disease (Late-onset), Inclusion Body Myositis | Unknown | LMU Klinikum | 95 | 2022-03-31 | 2023-10-10 | |
| Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD) FSHD | Recruiting | University of Kansas Medical Center | 450 | 2020-12-15 | 2026-05-07 |
Muscular Dystrophy, Facioscapulohumeral (5) · Facioscapulohumeral Muscular Dystrophy 1B (4) · Facioscapulohumeral muscular dystrophy 1a (3) · Muscular Dystrophies (3) · Cerebral Palsy (1) · Fatigue (1) · Glycogen Storage Disease Type II (1) · Muscular Atrophy, Spinal (1) · Muscular Dystrophies, Limb-Girdle (1) · Muscular Dystrophy, Duchenne (1) · Myositis, Inclusion Body (1) · Pain (1) · Spinal Muscular Atrophies of Childhood (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Genetic Diseases, Inborn (7) · Muscular Diseases (7) · Musculoskeletal Diseases (7) · Nervous System Diseases (7) · Neuromuscular Diseases (7) · Muscular Disorders, Atrophic (6) · Muscular Dystrophies (3) · Brain Diseases (2) · Central Nervous System Diseases (2) · Motor Neuron Disease (2) · Neurodegenerative Diseases (2) · Spinal Cord Diseases (2) · Brain Damage, Chronic (1) · Brain Diseases, Metabolic (1)
Sodium Chloride (2) · Blood Specimen Collection (1) · Vital Signs (1) · Walk Test (1) · Watchful Waiting (1) · apitegromab (1)
Avidity Biosciences, Inc. (3) · AbiliTech Medical Inc. (1) · FSHD Society (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · LMU Klinikum (1) · Radboud University Medical Center (1) · Scholar Rock, Inc. (1) · University of Kansas Medical Center (1)
United States (7) · Canada (4) · United Kingdom (4) · Germany (2) · Italy (2) · Brazil (1) · Denmark (1) · France (1) · Japan (1) · Netherlands (1) · Spain (1)
Amanda Hill, MBA (1) · Jeffrey Statland, MD (1) · Rabi Tawil, MD (1) · Stephan Wenninger, PD Dr. med. (1)