24 completed, 6 unknown, 4 recruiting, 2 terminated. 11 Not applicable, 6 Phase 1, 6 Phase 2, 3 Phase 3, 2 Phase 4.
Follow Vital Signs: new trials by email Literature Review of Vital Signs trials Research Report on Vital Signs
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Women's Heart: Impact of Ultra-endurance and Hormonal Profile on Cardiac and Systemic Inflammatory Parameters in Female Runners Echocardiography, Arterial ultrasound, Blood sampling - Healthy Volunteer | Not applicable | Not yet recruiting | French Cardiology Society | 120 | 2027-03-20 | 2026-10-09 |
| Safety and Psychological Effects of Psilocybin and D-Serine Formulation in Healthy Volunteers Psilocybin and D-Serine, Physical Examination, Vital signs - Healthy Volunteers | Phase 1 | Recruiting | Hadassah Medical Organization | 10 | 2025-12-11 | 2026-02-05 |
| Endoscopic Full Thickness Suturing of Mucosal, Submucosal and Perforation Defects Using Su2ura® GI System Su2ura® GI system, Physical Examination, Vital Signs - Endoscopic Mucosal Resection, Endoscopic Submucosal Dissection (ESD) | Not applicable | Recruiting | Anchora Medical | 25 | 2025-08-18 | 2026-01-07 |
| EWSs and 28-Day Mortality in Geriatric ED Patients Demographic Characteristics, Comorbidities, Vital Signs - Mortality, Clinical Deterioration | Completed | Haseki Training and Research Hospital | 2744 | 2025-07-01 | 2026-05-11 | |
| Efficacy of Sublingual 5-MeO-DMT for Reducing Anxiety and Depression in MCI Sublingual administration, Electroencephalography, Biochemical mesurements - Mild Cognitive Impairment, Anxiety State | Phase 1 / Phase 2 | Completed | Biomind Labs Inc. | 20 | 2024-12-15 | 2025-04-09 |
| Safety, Tolerability, and Efficacy of Sublingual Microdoses of 5-MeO-DMT for Depression and Anxiety BMND08, Brain electrical activity monitor, Pharmacokinetic Study of Sublingually Administered Psychoactive Substance - Healthy Volunteers | Phase 1 / Phase 2 | Completed | Biomind Labs Inc. | 40 | 2024-10-21 | 2025-03-05 |
| Stress Ball Use in Patients Undergoing Coronary Angiography The Effect of Stress Ball Use on Immobilization Comfort, Pain Level and Vital Signs in Patients Undergoing Coronary Angiography - Pain | Not applicable | Completed | Mustafa Kemal University | 72 | 2024-04-24 | 2024-07-08 |
| Clinical Trial to Evaluate the Efficacy and Safety of Codivir® in Addition to Standard Antiretroviral Treatment for HIV Infection in Antiretroviral-naïve Participants ICF, Eligibility Assessment, Demographic data - HIV, HIV Infection | Phase 2 | Recruiting | Code Pharma | 40 | 2023-07-20 | 2024-11-06 |
| Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening. Exhaled breath condensate sampling, Blood sampling, LDCT - Lung Cancer | Not applicable | Recruiting | The Institute of Molecular and Translational Medicine, Czech Republic | 3200 | 2023-06-01 | 2026-02-12 |
| Predicting if the Blood Pressure Will Drop After Spinal Anesthesia Using Ultrasound of the Neck Carotid ultrasound measurement, Vital sign measurement, Spinal anesthesia - Spinal Anesthesia-induced Hypotension | Completed | Catharina Ziekenhuis Eindhoven | 44 | 2023-04-12 | 2024-12-02 | |
| Proof of Concept Open Label, Clinical Trial to Evaluate the Safety and Efficacy of the "FITT" Device in Diabetic Foot Ulcers Patients Study treatment administration (TriO FITT), Physical Examination, Vital Signs - Diabetic Foot Ulcer | Not applicable | Completed | Tri.O Medical LTD | 19 | 2023-03-29 | 2026-10-08 |
| Assessment of KM-001 - Safety, Tolerability, and Efficacy in Patients With PPPK1 or PC KM-001 cream 1% 12 weeks treatment., Physical Examination, Vital Signs - Punctate Palmoplantar Keratoderma Type 1, Pachyonychia Congenita | Phase 1 | Completed | Orvida Pharma (formerly Kamari Pharma) | 18 | 2023-03-06 | 2025-01-15 |
| Validation of Prognostic Accuracy of ABC ( Age, Blood Urea Nitrogen , Co-morbidities ) and Horibe Pre-endoscopy Scoring Systems in Patients With Upper Gastrointestinal Bleeding in Sohag University Hospital . history taking , vital signs and labaratory investigations - Upper GI Bleeding | Unknown | Sohag University | 100 | 2023-02-15 | 2023-05-25 | |
| Feasibility of Using NeoSpot at Community Settings NeoSpot - Pregnancy Related | Completed | Centre for Infectious Disease Research in Zambia | 149 | 2023-01-15 | 2026-09-25 | |
| Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19 Biochemistry blood test, Hematology blood test, D-Dimer test (coagulation) - Covid19, Corona Virus Infection | Phase 2 | Completed | MGC Pharmaceuticals d.o.o | 240 | 2022-10-11 | 2023-03-15 |
| Study Designed to Evaluate Safety and Efficacy of 1% Topical Formulation of KM-001 on Type 1 Punctate Palmoplantar Keratoderma or Pachyonychia Congenita Diseases Serum chemistry, Hematology, Urinalysis - Punctate Palmoplantar Keratoderma Type 1, Pachyonychia Congenita | Phase 1 | Completed | Orvida Pharma (formerly Kamari Pharma) | 14 | 2022-07-17 | 2025-01-07 |
| Pompe & Pain - Study to Assess Nociceptive Pain in Adult Patients With Pompe Disease Beck depression inventory fast screen (Questionnaire), Brief Pain Inventory (BPI) (Questionnaire), German Pain Inventory (Questionnaire) - Pompe Disease (Late-onset), Inclusion Body Myositis | Unknown | LMU Klinikum | 95 | 2022-03-31 | 2023-10-10 | |
| Influence of Menstrual Cycle Stages on Female Athletes Determination of hormone level concentrations, Jump height determination, Grip strength determination - Menstrual Cycle, Sports | Completed | Universitat Jaume I | 41 | 2022-03-16 | 2022-12-21 | |
| Laparoscopic Ventral Hernia Repair with Routine Defect Closure Using Su2ura® Approximation Device Hernia repair surgery using the Su2ura® approximation device, Physical Examination, Vital Signs - Ventral Hernia | Not applicable | Completed | Anchora Medical | 18 | 2022-01-19 | 2025-01-21 |
| Detection of Exhaled Methane Levels in Hemorrhagic Shock Measurement of methane concentrations in exhaled breath, Videomicroscopy of the sublingual microcirculation, Blood gas and laboratory analysis - Hemorrhagic Shock, Trauma | Unknown | Szeged University | 40 | 2021-11-01 | 2021-09-28 |
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COVID-19 (3) · Anxiety Disorders (2) · Coronavirus Infections (2) · Depression (2) · Glycogen Storage Disease Type II (2) · Keratosis palmoplantaris papulosa (2) · Myositis, Inclusion Body (2) · Pachyonychia Congenita (2) · Pulmonary Disease, Chronic Obstructive (2) · Spinal Muscular Atrophies of Childhood (2) · Acquired Immunodeficiency Syndrome (1) · Adenomatous Polyps (1) · Cardiovascular Diseases (1) · Clinical Deterioration (1) · Cognitive Dysfunction (1)
Anchora Medical (2) · Biomind Labs Inc. (2) · LMU Klinikum (2) · MGC Pharmaceuticals d.o.o (2) · Orvida Pharma (formerly Kamari Pharma) (2) · Baylor Research Institute (1) · Catharina Ziekenhuis Eindhoven (1) · Centre for Infectious Disease Research in Zambia (1) · Chosun University Hospital (1) · Code Pharma (1) · David Hasan (1) · French Cardiology Society (1) · Hadassah Medical Organization (1) · Haseki Training and Research Hospital (1) · Hospital Clinic of Barcelona (1)
Israel (7) · United States (5) · Spain (3) · United Kingdom (3) · Argentina (2) · Denmark (2) · Germany (2) · Turkey (Türkiye) (2) · Belgium (1) · Brazil (1) · Canada (1) · Czechia (1) · Egypt (1) · France (1) · Hungary (1)
Martin A. Bruno, PhD (2) · Stephan Wenninger, PD Dr. med. (2) · Adem Az (1) · Albert Manasyan, MD (1) · Arthur Bouwman, Professor (1) · Carlos Hernando-Domingo, Doctor (1) · Craig S Conoscenti, MD (1) · Eladio Collado-Boira, Doctor (1) · Erika F. Christensen, MD, Medical director (1) · Isabel Blanco, MD, PhD (1)
PMID 19411668, PMID 26391583, PMID 28430315, PMID 32252135, PMID 32434791, PMID 33845761, PMID 34470496, PMID 35298560, PMID 35793921, PMID 37331563, PMID 40057795, PMID 40198758, PMID 40232947, PMID 40659913, PMID 41047463
R01HL142042 (1)